physio 5 last minute Flashcards by Natalie Slaughter

function of Ach

vasodilation
increased secretion
smooth muscle contraction

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upper esophageal spincter

closed during inspiration

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pyloric sphicter

regulates gastric emptying

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what is the source of CCK

duodenum

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what is the target of CCK

pancreas, gallbladder, stomach, spincter of oddi

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What is the function of CCK

incrase enzyme secrtion, incrase contraction, decrease gastric emptying, incrase relxation

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what is the target of gastrin

parietal cells, ECL, D cell

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what is the source of motilin

upper GI

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what is the target of motilin

stomach, doumon

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what is the source of peptide YY

ileum, colon

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what is the target of peptide YY

pancreas

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what is the action of peptide YY

decrease enzyme and fluid secretion

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what is the source of secretin

duodenum

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what is the target of secretin

pancreas, stomach

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what is the action of secretin

incrase bicarb secretion
decrease acid secretion
delay gastric emptying

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what is the source of somatostatin

stomach, duodenum, pancreatic cells

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what are the targets of somatostatin

stomach, intestine, pancreas, liver

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what is the action of somatostatin in stomach and intestine

decrease acid secretion, increase fluid absorption

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what is the action of somatostatin in pancreas, liver

decrease secretions

decrease bile flow

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what is the source of prostagland

stoamch, intestine/immune cells

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what is teh target of prostaglandin

stomach intestin

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what is the action of prostglandin on the stomach

inrease blood flow
decrease acid secretion
incrase mucus/bicarb secretion

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what is the action of prostaglandin on intestin

increas motility

increase fluid secretion

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what is the source of histamine

stomach,

intestine/immune cells

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what is the target of histamine

stomach | intestine

what is the action of histamine on the stomach

increase acid secretion

what is the action of histamine on the insteine

increase fluid secretion

what is the source of somatostatine

stomach | duodenum, pancraestic cells

what is the target of somatostatin

stomach, intestine

what is the actino of somatostatin on the stomach

decrease acid secretion | incrase fluid absorption

what is the action of somatostatin on the intestine

decrease smooth muscle contraction

what is the receptive relxation mediated by

what is gastric accomination regulated by

ENS

what hormones impair gastric emptying

secretin, CCK, gastrin

what neurotransmitters impair gastric emptying

Ach, 5-HT

what neurotransmitters promote gastric emptying

NO, VIP

what are the key neurotransmitters of the emetic response

serotonin, dopamine, ach, histamine

action of ach on stomach

promote HCL, mucus, bicarb secretion

what does superfirical epithelial cell release

mucus, bicarb

functions of gastric acid

``` protein digestion sterilization prevent bacterial and fungal growth facilitate absorption promote bile and pancreatic enzyme flow ```

what does gastrin act on

parietal cell

what does ach act on

parietal cell

what does histamine act on

neighboring parietal cell

what does somatostatin act on

g cells

what are regulators of interdigestive phase of gastric acid secretion

of partieal cells body weight presence of food in stomach

regulators of cephalic phase of gastric acid secretion

sight/smell of food

regulators of gastric phase of gastric acid secretion

distension of stomach | neg feedback if really low pH

regulators of intestinal phase of gastric acid secretion

peptides in duodenum | absorption of amino acid in duodenum

what are the 2 key stimuli for mucus secretion by epithelial and neck cells of the stomach

ach, prostatgland

what is the role of secretin in the stomach

decrease acid realease increases pepsinogen release delay gastric emptyin

zollinger-ellison syndrome

high serum gastrin levels | causes tumor in duodenum/pancrea

what are the 2 primary stimuli for fluid and enzyme secretion by pancreatic acinar cells

CCK | Ach

what is the primary stimulus for secretion of bicarb from pancreatic duct cells

secretin

what is the stimulis for cephalic phase of pancreatic secretion

sight, smell, taste, mastication

what is the stimulius for gastric phase of pancreatic secretion

distension, gastrin, peptides/peptones

what is the stimulis for intestintal phase of pancreatic secretion

amino acid fatty acid H_

how does somatostatine affect bile secretion

inhibits

how does CCK affect bile secretion

promote

what do brunners glands in duodenum secrete

mucus, bicarb

what cells does cryptos of liberkuhn in small intestine have

goblet, secretory enterocytes, absorptive entrocytes

what do secretory enterocytes secrete

electrolytes, water

what do absoptive enterocytes secrete

peptidase, sucrase, maltase, lactase, lipase, transpoters

where is folic acid absorbed

duodnum

what is important about folic acid

DNA synthesis and cell division

what happens when you have impaired folic acid uptake

anemia

stimulation of CFTR results in what

fluid secretion

what stimulates CFTR

Ach, VIP, 5HT, prostatgland, histamine, cholera, e coli

what does inhibition of Na-H exchanger cause

fluid secretion

what inhibits Na-H exhacnger

Ach, VIP, 5HT, prostalgandin, histamin, cholera, e coli

what does uptake of Na channels and Na/K ATPase cause

fluid absorption

what does icnrease of Na-H exchanger cause

fluid aborption

what causes uptake of Na channels and Na K ATPase

mineralocorticoid glucocorticoid

what causes incrase of Na-H exchanger

somatostatin enkephalin NE

defiiceny in what neurotransmitter could cause the problem of vomiting 3 year old

lack of Ach causing release of NO

what action does CCK have on gallbladder

contraction

what action does CCK have on pancreas

acinar secretion

what action does CCK have on stomach

reduce emptying

what action does CCK have on sphicter of oddi

relaxation

what does the pancreas help digest?

protein, carbs, lipids, nucleotides

what can obstruction in pancreatic duct cause

acute pancitis, elevated pancreatic enzymes, digestice impairment, weight loss, white stool

what can obstruction in common bile duct cause

elevation of bilirubin (jaundice) emuslifation of fat, elevated lipase

what postively regulates cryptos of liekerkun throughtout the large intestine

mechanical PNS ENS

how do you treat DKA

restoring plasma volume, reduce blood glucose, correct acidosis, replenish electrolite

physio 5 last minute Flashcards

(83 cards)