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Epi MT > Picornaviridae > Flashcards

Picornaviridae Flashcards

(62 cards)

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1
Q

Picornavirus vector

A

none

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2
Q

Aphtovirus main disease

A

FMD

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3
Q

Aviheptovirus main disease

A

Duck hepetatitis

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4
Q

Cardiovirus main disease

A

encephalomyocarditis

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5
Q

Enterovirus main disease

A

SVDV

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6
Q

Teschovirus main disease

A

Porcine teschovirus

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7
Q

Tremovirus main disease

A

Avian encephalomyelitis

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8
Q

TESCHOVIRUS ENCEPHALOMYELITIS has also been called

A

Teschen D (higher virulence)
Talfan D (lower virulence)

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9
Q

Teschovirus ST

A

serotype 1: virulence variants
* Teschen: higher virulence
* Talfan: lower virulence
serotypes 2-11:
* milder clinical signs, healing

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10
Q

Teschovirus susceptible species

A

only pigs

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11
Q

Teschen & Talfan disease species differrence

A
  • Teschen disease: clinical signs in all age groups
  • Talfan disease: clinical signs below 4 months (mainly 3-8 weeks), maternal immunity
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12
Q

Teschovirus epidemiology

A

spread in : meat, brain, faeces, swill
shed in faeces for 7-8wks
resistant in environment (indirect inf)

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13
Q

Teschovirus Pathogenesis

A

PO/ nose (CNS)
prim. rep.: lYmphoid tissue of GIT
(asymptomatic, shedding virus)
viraemic phase
neural phase (2nd virus rep)

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14
Q

Teschen Disease CS

A

piglets: ataxia, flaccid paralysis, resp paralysis
adults: flaccid paralysis
some may recover (mvmt disorders)

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15
Q

Talfan Disease CS

A

piglets below 4mths (before weaning)
transient paralysis of hindlimbs
recover, ataxia can remain

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16
Q

Crumbling mouvements is a CS of which disease

A

Teschovirus serotype 2

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17
Q

Teschovirus Patho

A

no gross patho
histo: necrosis, degeneration
- grey matter of the brian (ST2 also white matter)
- ventral horns of the spinal cord

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18
Q

Teschovirus diagnosis

A

RT-PCR

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19
Q

Teschovirus DDx

A

diseases with CNS signs
rabies, CSF, ASF, Aujesky, Glassers

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20
Q

Teschovirus prevention/ control

A

notifiable in HU
not OIE listed since 2005
no vaccines anymore

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21
Q

Swine vesicular Disease causative agent

A

SVD virus, enterovirus genus

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22
Q

Swine vesicular Disease susceptible species

A

only pigs

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23
Q

Swine vesicular Disease resistancy

A

good

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24
Q

Swine vesicular Disease Pathogenesis

A

PO
epitheliotropic virus
rep epithelium of throat and gut
viraemia
vesicles
CNS, heart & faetus (rare)

no mortality

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25
Swine vesicular Disease CS
vesicles: nose, oral mucosa, legs, (ruptured within 2dys) limping fast recovery
26
Swine vesicular Disease Diagnosis
RT-PCR VN, ELISA (to recognize asymptomatic carriers)
27
Swine vesicular Disease DDx
FMD Vesicular exanthema of swine Vesicular stomatitis Vesicular disease caused by Seneca virus A
28
Swine vesicular Disease Prevention/control
**notifiable D in HU** not WOAH listed no vaccines
29
Vesicular disease caused by Senecavirus A occurence
USA Chine Italy Brazil
30
Vesicular disease caused by Senecavirus A epidemiology
infection with discharges (indirect)
31
Vesicular disease caused by Senecavirus A CS
piglets below 1 wk (CNS sings) growers: vesicles on coronary band ## Footnote adults do not die
32
Avian Encephalomyelitis (epidemic tremor) occurence / atiology
clinical form not common (vaccination) tremovirus 1 ST highly resistant
33
Avian Encephalomyelitis (epidemic tremor) epidemiology
chicken, phaesants (all age) maternal protection for 3-6wks CS in 1-3wks old up to 4-5wk old spread: germinative, faeces (fast spread)
34
Avian Encephalomyelitis (epidemic tremor) lethality
high
35
Avian Encephalomyelitis (epidemic tremor) pathogenesis
PO rep mucous membrane of gut viraemia: pancreas, liver, ovarium (**does not kill it)** CNS shedding: faeces good immunity
36
Avian Encephalomyelitis (epidemic tremor) CS
nervous signs: tremor, ataxia, paralysis older animals: subclinical, egg prod drops by 5-10%
37
Avian Encephalomyelitis (epidemic tremor) patho
no gross lesions histo: CNS, grey matter degeneration of neurons
38
Avian Encephalomyelitis (epidemic tremor) DDx
NDV avian influenza Marek encephalomalacia
39
Avian Encephalomyelitis (epidemic tremor) prevention
fresh inf: no hatching for 1 mth vaccine: live vaccine in drinking water (at least 1mth before laying)
40
Duck viral hepatitis aetiology
ST1: now duck hepatitis A ST2: now astrovirus ST3: now astrovirus Duck hepatitis A virus 3 genotypes: G1: highly pathogenic G2 & 3: less pathogenic
41
Duck viral hepatitis epidemiology
inf: PO, NO germinative shed in faeces day old duckling: 90% mortality 2-3wks of age 50% mortality
42
Duck viral hepatitis pathogenesis
PO rep mucous membrane of GIT viraemia
43
Duck viral hepatitis immunity
long lasting, yolk immunity 3-6wks
44
Duck viral hepatitis CS
cs seen in young ducklings peracute: largescale death in a few hours acute: spasmodical paddling (opisthostonus, hunched back)
45
Duck viral hepatitis prevention
inactivated vaccine: layers (booster needed) attenuated: layers and day old duckling
46
encephalomyocarditis occurence
worldwide clinincal form is rare **zoonotic**
47
encephalomyocarditis host
wide host range maintained by rodents (asymptomatic) swine, elephant, etc
48
encephalomyocarditis mortality
new-born: 25-50% growers, fattening: 5-25%
49
encephalomyocarditis pathogenesis
PO rep in tonsils viraemia: - heart, myocarditis - SI: shedding - foetus: abortion - CNS: encephalomyelitis
50
encephalomyocarditis maternal immunity
4-6wks
51
encephalomyocarditis CS
piglets (4-5wks): heart failure, ataxia, paralysis growers: dyspnea, death sows: repro problems
52
encephalomyocarditis prevention/control
inactivated vaccines in some countries rodent control
53
mamastrovirus disease
human, swine, cattle, cat: gastroenteritis
54
Avastrovirus diseases
chicken astrovirus: Avian nephritis 1 & 2 duck astrovirus 1 & 2 turkey astrovirus
55
Astrovirus resistancy
very resistant
56
Avian nephritis epidemiology
only in chickens any age mortality 1-10% in the first week spread by faeces
57
Avian nephritis pathogenesis
PO rep: gut epithelium viraemia rep in epithelial c of proximal tubules
58
Avian nephritis CS
CS in first 4 wks day old chickens: diarrhea, kidney lesion chronic cases: visceral urate deposit & death
59
Avian nephritis patho
- enteritis - nephrosis - urate deposition in chronic cases
60
Avian nephritis diagnosis & prevention
RT-PCR no vaccines
61
duck hepatitis caused by astrovirus
CS & patho Diag & prevention just like duck hepatitis caused by Avihepatovirus
62
turkey astrovirus disease
2 ST CS : diarrhea in young

Epi MT (16 decks)

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