PoxViruses

Question 1

resistance of poxvirus

Answer 1

High (in scabs)

Question 2

what are called the poxvirus intracytoplasmic acidophilic inclusion bodies in mammals

Answer 2

Guarnieri body

Question 3

what are called the poxvirus intracytoplasmic acidophilic inclusion bodies in birds

Answer 3

Bollinger body

Question 4

Which poxvirus genus is zoonotic

Answer 4

Orthopox
Parapox

Question 5

Parapoxvirus genus

Answer 5

Bovine papular stomatitis, contagious pustular dermatitis, pseudocowpox, seal pox

Question 6

PoxVirus pathogenesis

Answer 6

aerogenic, PO, contact, arthropods
Primary rep locally
1. stadium erythematosum (reddened)
2. stadium papulosum (proliferatio, grey nodule)
3. stadium vesiculosum (cell necrosis, vesicle)
4. stadium pustulosum (pus)
5. stadium crustosum (dry crust)
6. stadium decrustationis (crust peel off)
7. recovery (with or without scar)

Question 7

which pox virus does not give a life long immunity?

Answer 7

Parapoxvirus

Question 8

PoxVirus vaccine

Answer 8

live virus vaccine

Question 9

attenuated poxvirus vaccine is against which disease

Answer 9

myxomatosis

Question 10

cowpox causative agent

Answer 10

cowpox virus

Question 11

cowpox carriers

Answer 11

rodents (25% seropositive)

Question 12

cowpox route of infection

Answer 12

contact, wounds

Question 13

cowpox epizootiology

Answer 13

rarely in cattle
entire stock is affected
immunity for years
zoonotic

from cattle to rat

Question 14

cowpox CS

Answer 14

mild fever, papules at inf. site
Rarely generalized
Haemorrhagic, red/black pustules, papules, (only rarely vesicles): udder, mouth, scrotal skin

not often generalized

Question 15

Cowpox recovery time

Answer 15

approx. 1 month

longer in poor hygiene conditions

Question 16

cow pox differential

Answer 16

Herpes mamillitis

Question 17

cowpox in other animals

Answer 17

rodents: subclinical, around the mouth
feline: asymptomatic or legs, upper resp symptoms
Hu: milking nodules on hands (immune suppresed can become generalized)
elephant, seal: generalized

Question 18

smallpox infect naturally

Answer 18

only people

Question 19

Variola major variants

Answer 19

Skin changes, generalized disease: 45% mortality,
The haemorrhagic form: 100% mortality

Question 20

variola higher mortality in which age group

Answer 20

young

Question 21

variola vaccination in 1700s

Answer 21

with cowpox, farmers & milkmaids suffered less from smallpox

Question 22

smallpox occurence

Answer 22

Earth is free from the 8th of May 1980

Question 23

Monkeypox occurence

Answer 23

endemic in central and west africa

Question 24

monkeypox occurence

Answer 24

endemic in central and west africa

Question 25

how lethal is monkeypox in humans

Answer 25

used to be 30% now lower due to small pox vaccination

Question 26

2022 monkeypox pandemic

Answer 26

almost only among bi- & homo-sexuals

Question 27

Pseudocowpox's virus from which genus

Answer 27

parapox genus

Question 28

pseudocowpox infects

Answer 28

cattle & humans: **Zoonotic**

Question 29

pseudocowpox in cows

Answer 29

mild, disease on udder and teat introduction of infected animals, infection by contact (hands, milking cups)

Question 30

pseudocowpox symptoms

Answer 30

lesions on udder and teat serous exudate on surface of papules | incubation 1 week ## Footnote short immunity = recurrent disease

Question 31

Bovine papular stomatitis infects what age group

Answer 31

mostly calves under 1 year old, but occurs at any age

Question 32

Bovine papular stomatitis immunity lasts for how long

Answer 32

short term

Question 33

Bovine papular stomatitis clinical symptoms

Answer 33

mucosal membranes, redness, papules (heals after few weeks) no fever, no other symptoms, but can be painful => weight loss

Question 34

Bovine papular stomatitis **zoonotic**?

Answer 34

yes

Question 35

Bovine papular stomatitis vaccine

Answer 35

none

Question 36

Contagious pustular dermatitis causative agent

Answer 36

Orf virus

Question 37

Orf virus resistancy

Answer 37

highly resistant | (12 yrs in dried crust)

Question 38

Contagious pustular dermatitis affects which animals

Answer 38

sheep, goat, humans mass disease in young lambs (after lambing season) | **zoonotic**

Question 39

Contagious pustular dermatitis pathogenesis

Answer 39

route of infection: mouth and foot injuries caused by rough feed papules, serous exudates, crusts

Question 40

Contagious pustular dermatitis CS

Answer 40

lesions lips, feet, udder, prepuce painful: no grazing, weight loss rarely papules in internal organs (GI, lungs & heart)

Question 41

Contagious pustular dermatitis vaccine

Answer 41

protects for 6 months: - Vaccine containing virulent virus: scarified into the skin in case of an outbreak - Attenuated virus: in injectable form, can also be used in non-infected herds (no viral shedding)