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Flashcards in Principles of Chemotherapy Deck (13)
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1

What is the cell cycle?

G0- resting
G1- RNA & protein synthesis
S- DNA synthesis
G2- cells constructing mitotic apparatus
M- cell division

2

What is PMAT

Prophase
Metaphase
Anophase
Telophase

3

What are the classes of chemo?

alkalating agents
antitumor anibiotics
antimetabolites
Vinca alkoloids
campthothecins
misc agents

4

alkalating agents

non specific

5

antitumor antibiotics

cell cycle specific phase nonspecific

6

antimetabolites

s phase

7

vinca alkolides

m phase

8

campthothecins

s phase

9

taxanes

m phase

10

podohyllotoxins

m phase

11

routes for administrations

systemic
-oral
-IV
-subcutaneous
-intramuscular
Regional
-intrathecal
-intraarterial
-intracavitary

12

Chemo side effects

severity of effects varies according to dosage, timing, duration, route of administration, prior chemo and radiation

13

what is MDR

multi drug resistant gene