Probability and Statistics Flashcards

1
Q

2 ways a study can screw the pooch

A

caused by chance (random error)

not caused by chance (bias or systematic error)

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2
Q

what deals with random errors

A

statistical inference

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3
Q

T/F random errors bias a study

A

false

may be wrong but not biased

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4
Q

what is a systematic error

A

error that is inherent to the study method being used and results in a predictable and repeatable error for each observation

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5
Q

T/F systemic errors bias a study

A

true

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6
Q

T/F there is a formal method to deal with systematic errors

A

false

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7
Q

tests of statistical inference

A

estimate the likelihood that a study result was caused by chance

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8
Q

T/F statistically significant means clinically important or meaningful

A

false

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9
Q

what is a chance occurrence

A

something that happen unpredictably without discernible human intention or with no observable cause

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10
Q

random variation

A

there is error in every measurement

if measure something over an over again will get slight variations in measurements

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11
Q

what does statistical inference tell us

A

if we measure something only once, how sure are we that our measurement has been caused by chance

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12
Q

what 2 methods are used to estimate random variation in a study

A

confidence intervals

p-values

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13
Q

T/F width of the CI is related to sample

A

true

  • small samples have large CI
  • large samples have small CI
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14
Q

T/F if the 95% CI for the OR does not include one the OR is statistically significant

A

true

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15
Q

T/F the same rules apply for OR, PR, RR when it comes to CI

A

true

if CI spans one they are statistically insignificant and there is no association

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16
Q

what do P-values estimate

A

whether a measured association was likely to have been caused by chance

17
Q

Does P-value give you information on size of sample and range of true value

A

it sure as shit doesn’t

18
Q

to be statistically significant p-value must be less than

19
Q

how do you calculate p-value

A

chi-squared test

student’s T-test

correlation

20
Q

null hypothesis

A

hypothesis of no association

21
Q

alternative hypothesis

A

the research question

there is an association between exposure and disease

22
Q

T/F we use p-values or CIs accept or reject the null hypothesis

23
Q

wha is a type 1 error

A

false positive

  • reject the null when it is not false
  • saying there is an association when there isn’t
24
Q

what is a type II error

A

false negative

  • not rejecting the null when it is false
  • saying there is no association when there is
25
types of data
categorical continuous
26
categorical data
broken into discrete categories - nominal - ordinal
27
continuous data
variable is numeric and can have any one of many possible values
28
nominal
named, not ordered | horse vs. donkey; stallion vs. gelding vs mare vs colt vs filly
29
ordinal
named ad ordered by nor constant value between ranks | neonate vs juvenile vs adult vs geriatric
30
describe categorical data
frequency distribution may be represented as a table or bar chart statistical test
31
describe continuous data
frequency distribution and histogram describe the center of the distribution describes the amount of dispersion describe the shape of distribution statistical tests
32
what is central tendency
describes the center of the distribution | mean, median, mode
33
what is dispersion (spread)
describes how closely the values are gathered around the center of distribution range, standard deviation
34
Chi-squared test
test of independence between 2 categorical variables p-value used for categorical data
35
student's T-test
difference in means compare averages of 2 groups used for continuous data H0=means of 2 groups are the same Ha= can be one or two tailed
36
correlation
measures the strength and direction of a linear relationship between 2 continuous variables
37
correlation coefficient (r)
often used for dose response relationships both variables are numerical, usually continuous - strong: r>0.80 - weak: r