protein a/a Flashcards

(56 cards)

1
Q

daily protein req

A

0.83g per kg body weight

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2
Q

define transamination

A

making 1 non-essential aa from another

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3
Q

deamination

A

stripping an aa of nitrogen and using for energy

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4
Q

deamination req

A

B6

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5
Q

2 factors protein quality

A

its digestibility

its aa composition - all ess a/as in right amounts

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6
Q

food with perfect aa score

A

egg

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7
Q

two effects of high protein intake

A

increased calcium excretion

kidney stress

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8
Q

4 a/a function

A

detoxify chemicals
antioxidant protection
build bile acids for digestion
help make hormones, NTs

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9
Q

2 functions glutamnine

A

intestinal repair/protection - strengthening epithelial tight junctions
immune modulator - stims lymphocytes/ NK cells

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10
Q

what effect does cortisol have on glutamine

A

high cortisol

low glutamine

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11
Q

4 applications of glutamate

A

intestinal permeability
chemo/radiation side effects
peptic ulcers - cabbage juive
HIV

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12
Q

Function of glutamate/glutamic acid

A
principle excitatory a/a in brain
involved in movement
cognition
memory
sensation
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13
Q

G makes G makes G (smaller, med, bigger)

A

glutamine > glutamate > glutathione

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14
Q

glutathione is a tripeptide made of

A

cysteine

glutamate\glycine

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15
Q

is glutamate neurotoxic

A

yes msg

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16
Q

3 a/a urea cycle

A

arginine
ornithine
citrulline

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17
Q

action of arginine

A

dilates arteries

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18
Q

3 clinical applications arginine

A

lower BP - preciser to Nitric oxide
erectile dysfunction
angina

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19
Q

BCAA are which 3 a/a

A

leucine
isoleucine
valine

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20
Q

main effect of BCAA

A

stims protein synthesis - muscle sparing in exercise

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21
Q

def in BCAA symptom

A

anorexia low appetite

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22
Q

BCAA increases

A

appetite

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23
Q

why does BCAA increase appaetite

A

competes with TRYPTOPHAN for uptake across BBB - same transport mechanism
tryptophan preciser to seratonin - decreases appetite

24
Q

sulphur a/as

A

methionine

cysteine

25
cysteine synthesised from
methionine
26
what does methionine get converted into
SAM - major methyl donor
27
methionine req for synthesis of
acetylcholine creatine epinephrine
28
cysteine a component of which 3 substances
glutathione coenzyme A taurine
29
synthesis of B3 from tryptophan dependant on which 3 nutrients
B6, B2, iron
30
3 side effects of methionine
can increase homocysteine levels- esp if def in B6,9,12 | aggravate liver/kidney disease
31
cysteine req for which liver pathway
phase 2 detox - sulphating as source of sulphate
32
source of cysteine
cruciferous veg
33
antioxidant a/a
``` cysteine glutamate glycine - glutathione methionine (taurine) ```
34
what does cysteine make
NAC - N-acetyl cysteine
35
3 functions NAC
detoxifies antioxidant antiinflammatory
36
clinical application cysteine
thins mucous - bronchitis, COPD, flu
37
3 functions carnitine
cellular energy production gets long-chain fatty acids into mitochondria for oxidation reduces cellulite lowers triglycerides in blood
38
2 therapeutic uses carnitine
congestive heart failure | infertility
39
1 function creatine
increases performance in strength-related sports
40
glycine is a
neurotransmitter
41
smallest a/a
glycine - gets through BBB
42
function glycone
binds to toxic substances to be excreted
43
which a/a is not officially an a/a
taurine
44
primary function taurine
antioxidant
45
3 a/a cross BBB
glycine phenylalanine theanine
46
what type of people is taurine essential for and why
neonates/anyone on parenteral nutrition - avoids cholestasis
47
thiamine found in
green tea
48
3 effects of theanine
calming improves concentration mod enhancing
49
which a/a is precursor to thyroid hormone, dopamine, epinephrine, melanin
tyrosine
50
when is it contraindicated to take tyrosine
antidepressants MAOIs skin cancer
51
3 sources tryptophan
dairy turkey rice
52
tryptophan key for production of which 2 nutrients
niacin | seraotinin
53
3 therapeutic uses tryptophan
hyperactivity weight loss/apetite reduction improves stress/anxiety jet lag
54
which a/a good for herpes
lysine
55
which a/a could cause herpes
arginine
56
why could long term supplemental a/a create imbalance
as compete for transport through cell membranes