Protein structure and function Part 2

Question 1

What are the 4 types of the secondary structure

Answer 1

alpha helix
beta sheets
turns
random coil

Question 2

What’s the shape of a alpha helix

Answer 2

spring shape

Question 3

What is the backbone made up of in the alpha helix

Answer 3

H-bonds parallel to the spring

Question 4

In an alpha helix the Hbonding pattern repeats with every how many residues

Answer 4

4

Question 5

How is the beta sheet formed

Answer 5

between different parts of the amino acid sequence

Question 6

In a beta sheet how do the chains run

Answer 6

in alternating pairs and both parallel and anti-parallel

Question 7

What characteristics of residues disrupt a beta sheet

Answer 7

Clusters of bulky groups
clusters or similarly charged residues
proline can only form H in one direction

Question 8

2 characteristics of a random coil

Answer 8

flexible regions of a protein
found on the surface called surface loops

Question 9

2 properties of loops

Answer 9

equil with random coil and alpha helix organised by 2nd molecule
important in protien protien recognition involves chemical chain attachment of phosphate

Question 10

True or false :In a beta turn the protein chain turns sharply

Answer 10

true

Question 11

What is B-turn dependent on?

Answer 11

H-bond on 1st and 3rd peptide bonds in turn

Question 12

What is Beta turn often found linking

Answer 12

anti-parallel Beta sheets

Question 13

What is a tertiary structure

Answer 13

3D shape pf the protein called the fold

Question 14

What are the reasons on why we cannot predict tertiary structure

Answer 14

delicate eqil doesnt take much to wreck it (mutation)
genetic diseases caused by this