Protein structure and function part one Flashcards
(16 cards)
What is a protein
A molecule made up of amino acids
What’s an amino acid
Contains 2 functional groups amine and carboxylic acid and side chain
Each amino acid is called a …
residue
An amino acid is numbered starting and ending with what termini
N-terminus and C-terminus
Are peptide bonds polar or non-polar
polar
How is a peptide group formed what does the nitrogen and oxygen have
N lone pairs (delocalised)
oxygen patial -ve charge
What are sidechains also known as
R group
A small side chain means …
more flexible
Amino acids are classified as
hydrophobic and hydrophillic
amide bond partial makes the bond …
harder to rotate
Trans or cis the most stable
Trans
What are the properties influenced by in ionisation of amino acids
ionic states of carboxyl and amino groups
The ionisation of amino acids contain both …
acidic and basic forms
What is the primary structure
linear sequence of amino acids in protien form
Define homologous
sequences that can be aligned
What are the uses of primary structure
genetic diseases due to single amino acid mutations
human genome project - gives sequences of all human proteins