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Flashcards in PSA Deck (21):
1

This is a protein made by the prostate

PSA

2

What is PSA secreted by?

-Normal and neoplastic prostate tissue

3

What is the function of PSA

-Dissolve clotted semen and allow sperm to migrate upward into the female genital tract

4

T/F- PSA is a reliable immunocytochemical marker for primary and metastatic adenocarcinoma of the prostate

True

5

When is PSA high?

-Increased in most men with prostate cancer
-Increased with benign entities
-Indicator of recurrent adenocarcinoma post surgically

6

What can be performed to evaluate the size of or abnormalities of the prostate

DRE

7

What should a normal prostate feel like?

-Smooth, soft, and non-tender

8

Is the DRE recommended annually for the screening of prostate cancer?

NOPE

9

When is further evaluation warrented for prostate screening?

-When abnormalities are found on a DRE
-Patient complaints are present

10

What are S&S of prostate problems?

-Dribbling
-Frequency
-Trouble starting a stream

11

When should screening be discussed

At age 50

12

How do co-morbidities play a role in the discussion of prostate screening?

-If the co-morbidity limits their life to less than 10 years, there is no point in prostate screening because their comorbidity will kill them before their prostate will

13

When do men with a history of prostate cancer be screened?

at 45

14

Does PSA increase with age

Yes it does

15

Describe the sensitivity and specificity of PSA

Not specific or sensitive

16

What are some causes of PSA elevation

-Prostate cancer
-Prostate manipulation
-Benign prostatic hypertrophy
-Infection
-Inflammation

17

A DRE can _________ PSA

Increase

18

How many hours after a DRE can PSA be taken?

48-72 hours after
-if drawn before there can be falsely elevated levels

19

Do you know what PSA level is dangerous?

No- because the levels increase in age and there isn't a set good number or a bad number

20

When is a biopsy of the prostate warrented?

-if the DRE shows a nodule or mass
-if PSA has increased significantly

21

why isn't this saving

I don't even know