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Flashcards in Variation in Lab tetsing Deck (35):
1

Physiological state changes may result in...

abnormal lab tests

2

Meals stimulate the production of...

Gastric acid

3

What happens to HCl, pH, and plasma chloride concentration when you eat?

-Decrease HCl
-Increases pH
-Decrease plasma Cl

4

What does glucose absorption do?

-Stimluates the release of insulin
-Insulin causes the uptake of K into cells
-Decreasing plasma K levels (hypokalemia)

5

Non-fasting samples may result in _____ test results?

Abnormal

6

When are the most reproducible test results obtained?

When the patient is fasting for 8-12 hours

7

What effects does stress have on test results?

Stress increases your BV, and then increased your BP
-Increased BV causes a dilution of plasma proteins

8

As a clinician, what should you do if your patient is under stress?

Don't order elective testing if your patient is under stress

9

Describe the effects of exercising

Patients who exercise regularly have increased levels of plasma enzymes

10

What are examples of plasma enzymes?

-Creatinine kinase
-Asparate aminotransferase
-Lactate dehydrogenase

11

Where are plasma enzymes found?

The liver

12

What are high levels of plasma enzymes often confused with?

Liver disease

13

Describe cyclic variation

Reproducible patterns of alteration in physiologic state that occur at specific days, months, or year

14

What is an example of cyclic variation?

Pituitary hormones

15

What type of variation do pituitary hormones demonstrate?

Ultradian variation

16

Define Ultradian variation

Variation occurring in less than a day

17

How are pituitary hormones released?

Episodic bursts (results in periods of peaks and valleys)

18

Example of cyclic variation

Cholesterol is 25% higher during the 2nd half of the menstrual cycle

19

What effect do diaretics have?

They pull of fluid, sodium, and potassium

20

What happens when a patient is in an upright position?

-Water and electrolytes are lost from the vascular space
-Proteins and protein bound substances become very concentrated

21

What happens when you go from a sitting to a supine position?

Water and electrolytes move back into the vascular space
-Reduces the concentration of proteins by 10-15%

22

What happens if you have high venous pressure?

-The return of water and electrolytes to venous blood is impaired
-This increases the concentration of proteins and protein bound substances

23

How much does concentration increase after 3-5 minutes of tourniquet time?

5%

24

How much does concentration increase after 10-15 minutes of tourniquet time?

15%

25

As venous pressure remains high, circulation of fresh blood ______

Decreases

26

What happens when the circulation of fresh blood decreases?

The cells continue metabolizing and the glucose decreases and lactate increases

27

What does increased lactate result in?

Acidosis

28

What does acidosis do to potassium?

Leads to leakage of K from cells, and elevates serum K levels

29

What happens when you clench your fists?

Accelerates the rate that metabolic changes occur
-Increases serum K by 1-1.5 mmol/L in 1 minute

30

If a patient has an IV, where do you take the blood sample from?

-Below where the IV is placed

31

What color is the tube for... CBC?

Lavender

32

What color is the tube for... metabolic panels

Red

33

What color is the tube for... lipid profiles

red

34

What color is the tube for...Thyroid function tests

red

35

What color is the tube for... coagulation studies

blue