Rate-determining Regulators Flashcards Preview

First Aid Rapid Review KAM > Rate-determining Regulators > Flashcards

Flashcards in Rate-determining Regulators Deck (12):
1

Fructose-1,6-bisphosphatase (Gluconeogenesis)

- AMP, F-2,6-BP

2

Isocitrate dehydrogenase (TCA)

+ ADP
- ATP, NADH

3

Glycogen Synthase (Glycogenesis)

+ G-6-p, insulin, cortisol
- epinephrine, glucagon

4

Glycogen phosphorylase (Glycogenolysis)

+ epinephrine, glucagon, AMP
- G-6-P, insulin, ATP

5

G6PD (HMP)

+ NADP+
- NADPH

6

Carbamoyl phosphate synthase 2 (de novo pyrimidine)

+ ATP, PRPP
- UTP

7

Glutamine-PRPP amidotransferase (de novo purine)

- AMP, IMP, GMP

8

Carbamoyl phosphate synthase 1 (urea cycle)

+ N-acetylglutamate

9

Acetyl-CoA carboxylase (fatty acid synthesis)

+ insulin, citrate
- glucagon, palmitoyl-CoA

10

HMG-CoA synthase (Ketogenesis)

No regulators

11

HMG-CoA reductase (cholesterol synthesis)

+ insulin, thyroxine
- glucagon, cholesterol

12

Phosphofructokinase 1 (glycolysis)

+ AMP, F-2,6-bp
- ATP, citrate