RED ARROWS (Robia) & UNDERLINED (Ozark) Flashcards Preview

FHB - Endocrinology (by Richie) > RED ARROWS (Robia) & UNDERLINED (Ozark) > Flashcards

Flashcards in RED ARROWS (Robia) & UNDERLINED (Ozark) Deck (79)
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1

Meiosis II of ovum is completed at

fertilization (discontinuous)

2

Spermatogenesis results in how many germ cells

4

3

Oogenesis restults in how many germ cells

1

4

Normal sperm production requires

reduced temp

5

What receptor (and where) is upregulated in pregnancy promote cause GERD?

B-receptors on LES

6

What steroid hormone peaks during labor, and promotes partuition?

cortisol

7

What is progesterone's role during pregnancy?

maintains uterine quiescence and sustains fetus

8

What is estrogen's role during pregnancy?

Promotes partuition, increases sensitivity to OXY

9

Ovary development depends on presence of

2x and no y

10

loss of one x results in

ovarian dysgenesis but no lose of female ducts or genitalia (turners)

11

How is it possible to have XX male and XY female?

presence or absence of XY, respectively

12

What promotes relaxin? What does it do?

hCG promotes relaxin. It relaxes the pelvic bones (looser)...

13

XY without SRY looks like

turners

14

When male hormones are absent, default is

female genital tract, external genitals

15

What blocks 5-alpha reductase?

Propecia (finesteride)

16

XO is

turners

17

Seminifereous tubule dysgenesis disease

XXY klinefelters

18

What causes male pseudohermaphroditism

Androgen resistance

19

Main cause of congenital adrenal hyperplasia

21 hydroxylase deficiency

20

21 hydroxylase deficiency main cause of

CAH

21

Lack cortisol/aldosterone. Main cause

CAH - 21 hydroxylase deficiency

22

slide 21...

COME BACK TO THIS

23

clitoromegaly....retention of urogenital sinus and fusion of labia...these features are exhibited in

female pseudohermaphroditism ... virilization by androgens....

24

T to E2

aromatase

25

T to DHT

5-alpha hydroxylase (blocked by propecia, finesteride)

26

Male pattern baldness caused by

DHT

27

What is the function of the intercellular bridges between secondary spermatocytes?

Synchronizes development, sharing resources...large enough to pass organelles by MT's

28

What's an acrosome?

A cap of membrane containing digestive enzymes

29

Continuous exposure (not pulsatile) of GnRH

inhibitory FSH and LH release

30

What keeps T high near developing sperm?

ABP from sertoli cells (which are stimulated by T and FSH)