Most common genetic cause of renal failure in the uK
ADPKD
In the majority of patients, where is the abnormality located in ADPKD
chromosome 16
What are the none cystic changes in ADPKD
Mitral valve prolapse
Intracranial berry aneurysms
Colonic diverticula
RCC
Which common vaccine is used in the treatment of none invasive bladder cancer?
BCG
90% of bladder cancers are what type?
Transitional cell
Main risk factors in bladder cancer
Age and smoking
Referral criteria for suspected bladder cancer pathway
> = 45 with haematuria and no UTI or haematuria following treatment of uti
Triad seen in HUS
thrombocytopenia, renal failure, haematuria
most common cause of acute renal failure in children
hus
Classic presenting feature of HUS
Diarrhoea that turns bloody 1-3 days later
Management of stress incontinence
- Exercises
- Duloxetine or referral
Management of urge incontinence
- Bladder retraining
- Anicholinergics such as oxybutynin or mirabegron if CI
Commonest cancer in men aged 15-34
testicular cancer
90% of varicoceles occur on which side?
Left
Management of painful bladder syndrome
- lifestyle, TENS, therapy
- Amitryptiline, icy, gabapentin, ciclosporin
Most common cause of pyelonephritis
E.Coli
Side effects of alpha blockers
Floppy iris syndrome
Postural hypotension
Ejaculatory dysfunction
Side effects of 5 alpha reductase inhibitors
decreased libido
erectile dysfunction
gynaecomastcascia
Most common cause of painless haematuria >60y
Transitional cell carcinoma
CI of nitrofurantoin
eGFR <45
Porphyria
G6PD def
Second line abx in uncomplicated UTI women
Pivmecillenam
UTI in pregnancy options
- Nitro
- Amox or cefalexin
How is amyloidosis diagnosed?
Congo red stain which fluoresces bright green
Hydroceles lie in what position relative tot he testis
Superior and anterior
