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Y4 Nephrology/Urology > Renal tumours > Flashcards

Flashcards in Renal tumours Deck (20)
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1

What are the risk factors for renal cell carcinoma?

obesity
smoking
HTN
dialysis

2

What are the risk factors for transitional cell carcinoma?

smoking
aromatic amines
cyclophosphamide

3

what inheritable renal cell carcinoma is there?

VHL syndrome

4

what are the subtypes of renal cell carcinoma?

clear cell
papillary
chromophobe
collecting duct

5

what is the triad of renal cell carcinoma presentation?

haemtauria
loin mass
loin pain

6

what % of renal cell carcinoma is asymptomatic?

50%

7

what paraneoplastic features can occur with renal cell carcinoma?

EPO - polycytheaemia
PTHrP - hypercalcaemia
renin - HTN
ACTH - cushings
amyloidosis

8

what could be seen on CXR with renal cell carcinoma?

cannon ball mets

9

what staging is used for renal cell carcinoma?

Robsons staging

10

what is the management of renal cell carcinoma?

Radical nephrectomy
 Consider partial if small tumour or 1 kidney

Temsirolimus (mTOR inhibitor)
-for poor prognosis

11

where is the most common locatoin for transitional cell carcinoma?

bladder

12

what is the presentation of transitional cell carcinoma?

Painless haematuria
 Frequency, urgency, dysuria
 Urinary tract obstruction

13

what is the management of transitional cell carcinoma?

 Nephrouretectomy

14

what is another name of nephroblastoma?

Wilms tumour

15

what cells cause nephroblastoma?

Childhood tumour of primitive renal tubules and
mesenchymal cells

16

what is nephroblastoma associated with?

Chr 11 mutation
WAGR syndrome

17

what does WAGR syndrome stand for?

wilms
aniridia
GU abnormalities
retardation

18

state some benign neoplasms of the kidneys ?

cysts
renal paillary adenomas
oncocytoma
angiomyolipoma

19

what condition is angiomyolipoma seen in?

tuberous sclerosis

20

what neoplasm is associated with chronic infected staghorn calculi ?

SCC