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Y4 Nephrology/Urology > BPH > Flashcards

Flashcards in BPH Deck (11)
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1

what cells are hyperplasic in BPH?

stromal
epithelial

2

What area is affected by BPH?

inner (transitional) layer

3

What molecule causes proliferation of stromal cells in the prostate?

DHT

4

what is DHT produced from?

produced from tetosterone in stromal cells by 5 alpha reductase enzyme

5

can a median sulcus be felt on DRE with BPH?

yes

6

what investigations should be done for BPH?

U&Es, PSA
urinalysis
TRUS and biopsy
urodynamics
voiding diary

7

name a alpha blocker?

tamsulosin

8

name a 5alpha reductase inhibtor?

finasteride

9

what is a side effect of 5alpha reducatse inhibitors?

excreted in semen (use condoms)

10

what is a side effect of alpha blockers

drowiness
hypotension
depression
weight gain
extra pyramidal signs

11

what is a complication of TURP?

impotence
retrograde ejaculation
uretheral stricture
incontinence