Respiration 4 Flashcards

(44 cards)

1
Q

ventilation

A

air getting to alveoli

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2
Q

perfusion

A

air getting to the tissue

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3
Q

Is blood pressure or ventilation higher at the base of the lung?

A

blood pressure

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4
Q

At the apex of the lung is blood pressure or ventilation higher?

A

ventilation

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5
Q

at what point in teh lung does ventilation and perfusion natulary reach equiliburm

A

rib 3

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6
Q

what declines faster blood flow or venaltion

A

blood flow

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7
Q

what percent of the lung preforms the correct ventilation to profusion ratio without other help

A

about 75%

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8
Q

what mechanism happens if blood flow is better than ventalation

A

decreaesd blood flow to that area an will move to an area with less blood flow

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9
Q

what happens if ventaltion is greater than bloodflow

A

increaseed blood flow to area due to vasco dilation

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10
Q

shunt

A

passage of blood through an area of lung that is poorly ventalated

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11
Q

areloare dead space

A

an alveoi that is ventalated but not perfused with blood

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12
Q

physilog dead space

A

aveloiar dead space + anatomical dead space

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13
Q

what happesn do heart reate during inspiration

A

increases

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14
Q

what happens to heart rate during expiration

A

decreased

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14
Q

why does heart rate change during breathing

A

otherwise alveolar deadspace would increase during inspiration and shunt would increase during exspiration, so maintains constant perfusion

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15
Q

how much 02 is dissolved in plasma per liter

A

3ml

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16
Q

how much 02 is disleved into haemoglovib per liter

A

197ml

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17
Q

how mcuh of c02 is transported in plasma and in haemoglobing

A

77% plasma, 23% haemoglobin

18
Q

how much oxygen is used perminute by cells
how much oxygen is delivered to each cells per min

A

250 ml/min
1000ml/min

19
Q

how many oxygen molues does 1 haemoglobin carry

20
Q

what are the 3 componiati of haemolgobin

A

2 a chain
2 b chain
4 heme gropus

21
Q

what does teh heme grpu contain

22
Q

how long does saturation take of haemogloigin

A

0.25s of the 1 s it is incontact

23
Q

how does the oxygen get to the haemoglobin

A

dissolves into plasma than pased ot the plasma, dissolved into it

24
what happens to hamogbin saturati as you decrase oxygen pressure
small change inital til baout 40% than a very large change
25
anaemia
compromise to carrying cappacity of the blood
26
does po2 change in anaemia
no, as long as the totla cell no stays the same
27
what factors affect the dissocatio curve of oxgygen
ph, co2, temp. dpg
28
how does ... affect the dissocaotion curve a. ph b. temp c. conc. of co2 d. dpg
a. ph increased - increased affinity for 02, ph decreased, reduced affinity for 02 binding to haemoglobin b. temp increased, decreased affinity for 02, temp decreased increased affinity for 02 c. pco2 increased decreased affinity for 02, decreased pc02 increased affinity for 02 d.dpg - affinity of haemoglobin decreased by increased dpg, helps to
29
dpg role
2,3 diphosphoglycerate , its syntesied by erythocytes, it is increased when there is low blood supply due to heart/lung disease or high alitidue
30
how many times greater is teh affity of CO compared with o2
250times greater
31
what is the treatement for co
100% 02
32
signs of co poisioning
amaemia, nausia, hyposix, cherry red skin and mucous memanes, normal respiation rate to normal co2 levels
33
what perent of c02 is dissovled in the plasma
7
34
what percent of c02 binds with haemoglobin and where does it occur
23 in eryotyces
35
What happens to the remaining c02 that does not bind with haemoglobin or is dissolved in plasma
Binds with h20 in the erythrocytes, and forms carbonic acids, it then removes h+ to form bicarbonate acid, the cl- ions replace the bicarbonate and the h+ binds to remain haemoglobin. This then all happens in reverse
36
What is the main form of haemoglobin?
hba (92%)
37
what is hba2
delta reapace b chain
38
What is HDF
gamma chain replace b chainS
39
what are hba1a, hba1b and hba 1c
glycosylated hb
40
What is myoglobin
It only has one polypeptide chain, found in cardiac and skeletal muscle
41
5 types of hypoxia
hypoxaemic reduced o2 to lungs , anaemic reduced the ability of blood to carry oxygen , stagnant reduced cardiac output , histotoxic posing stopping cells from using oxygen delivered, e.g. carbon monoxide , metabolic oxygen delivered to tissues to meet increased oxygen demand by cells
42
What is the difference between arterial partial pressure and arterial 02 content?
partial pressure is the pressure exerted by the oxygen on the blood, , arterial 02 content amount of o2 in 100ml of blood
43
Can gas travel in a gaseous stage in blood?
No, air bubbles will form.