S2E3: Abx Flashcards Preview

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Flashcards in S2E3: Abx Deck (74):
1

Beta lactam abx (classes)

penicillins, cephalosporins, carbapenems, monobactam abx.
Bactericidal.

2

Penicillin G

Natural penicillin. IV/IM.

3

Penicillin V

Natural penicillin. PO.

4

Cloxacillin

Anti-staph penicillin (penicillinase resistant)

5

Nafcillin

Anti-staph penicillin (penicillinase resistant)

6

Oxacillin

Anti-staph penicillin (penicillinase resistant)

7

Ampicillin

Extended spectrum penicillin (anti-strep pneumo)

8

Amoxicillin

Extended spectrum penicillin (anti-strep pneumo)

9

Piperacillin

Extended spectrum penicillin (antipseudomonal)

10

Ticarcillin

Extended spectrum penicillin (antipseudomonal)

11

beta-lactamase inhibitor

Used in combination with penicillin (increases spectrum)

12

Augmentin (amoxicillin + clavulanic acid)

penicillin + beta-lactamase inhibitor

13

Unasyn (ampicillin + sulbactam)

penicillin + beta-lactamase inhibitor

14

Timentin (ticarcillin + clavulanic acid)

penicillin + beta-lactamase inhibitor

15

Zosyn (piperacillin + tazobactam)

penicillin + beta-lactamase inhibitor

16

cefaxdroxil (duricef)

1st gen cephalosporin

17

cefazolin (ancef)

1st gen cephalosporin

18

cephalexin (keflex)

1st gen cephalosporin

19

cefuroxime (ceftin, zincef)

2nd gen cephalosporin

20

cefprozil (cefzil)

2nd gen cephalosporin

21

cefixime (suprax)

3rd gen cephalosporin

22

ceftazidime

3rd gen cephalosporin

23

ceftriaxone (rocephin)

3rd gen cephalosporin

24

cefdinir (omnicef)

3rd gen cephalosporin

25

cefepime (maxipime)

4th gen cephalosporin

26

ceftaroline (teflarco)

5th gen cephalosporin

27

aztreonam

monobactam

28

imipenem

carbapenem

29

ertapenem

carbapenem

30

meropenem

carbapenem

31

doripenem

carbapenem

32

Cell wall abx (non-lactams)

vancomycin, daptomycin, fosfomycin, cycloserine.

33

Vancomycin

cell wall abx. bactericidal (slow)

34

daptomycin

cell wall abx. bactericidal.

35

fosfomycin

cell wall abx. bactericidal (urine only)

36

cycloserine

cell wall abx. bacteriostatic at [low]; bactericidal at [high]

37

Protein synthesis inhibitors (inhibits ribosomes)

bacteriostatic: tetracycline, macrolides, clindamycin, oxazolidones.
bactericidal: aminoglycosides.

38

doxycycline (vibramycin)

tetracyclines

39

demecloclycline (declomycin)

tetracyclines

40

minocycline (minocin)

tetracyclines

41

oxytetracycline (terramycin)

tetracyclines

42

tigecycline (tygacil)

tetracyclines

43

erythromycin

macrolide

44

clarithromycin (biaxin)

macrolide

45

azithromycin (zithromax)

macrolide

46

fidaxomicin (dificid)

macrolide

47

telithromycin (keteck)

macrolide

48

clindamycin

inhibits bacterial ribosomes

49

linezolid (zyvox)

oxazolidinones

50

neomycin

aminoglycoside

51

streptomycin

aminoglycoside

52

amikacin

aminoglycoside

53

gentamicin

aminoglycoside

54

tobramycin

aminoglycoside

55

kanamycin

aminoglycoside

56

metronidazole (flagyl)

disrupts DNA helix. Bactericidal.

57

Folic acid synthesis inhibitors

Sulfonamides, TMP. Bacteriostatic.

58

sodium sulfacetamide (Bleph 10)

topical sulfonamide

59

silver sulfadiazine (silvadene)

topical sulfonamide

60

sulfasalazine (azulfidine)

oral sulfonamide

61

sulfadiazine

oral sulfonamide

62

sulfamethoxazole

oral sulfonamide

63

sulfisoxazole

oral sulfonamide

64

TMP/SMP (bactrim)

TMP (folic acid synthesis inhibitor- step 2) + sulfa drug (folic acid synthesis inhibitor- step 1)

65

Fluoroquinolones

inhibit topoisomerase. bactericidal.

66

ciprofloxacin (cipro)

fluoroquinolones

67

gemifloxacin (factive)

resp fluoroquinolones

68

levofloxacin (levaquin)

resp fluoroquinolones

69

moxifloxacin (avelox)

resp fluoroquinolones

70

norfloxacin (noroxin)

fluoroquinolones (for UTI only)

71

ofloxacin (floxin)

fluoroquinolones

72

gatifloxacin

fluoroquinolones

73

nitrofurantoin (macrobid)

inhibits acetyl CoA. bacteriostatic.

74

Antimycobacterial drugs

isoniazid (INH), Rifampin, Ethambutol, Pyrazinamide, streptomycin.
*streptomycin is aminoglycoside