SA: Osteoarthritis Flashcards
(5 cards)
1
Q
How can OA be prevented?
A
Breeding
Nutrition (Ca, calories)
Spay/neuter
2
Q
How do we calculate RER?
A
3
Q
What are important dietary restrictions for patients with OA?
A
<10% of caloric intake dedicated to treats
Reduce calorie consumption!
Aim for 1-2% weight loss per week
4
Q
MOA: Omega 3 Fatty Acids
A
Anti-inflammatory
Competes with arachidonic acid as substrates for COX and LOX enzymes
May also reduce MMP activity
5
Q
PSGAGs
A
Catabolic enzyme inhibitor
Enhances anabolic activity of chondrocytes and synoviocytes (HA, collagen, PGs)
Bind to cartilage matrix to prevent further degradation
