SAS#19

Question 1

Lower serum levels of cholesterol and various lipids. They are also called as lipid-lowering agents

Answer 1

ANTIHYPERLIPIDEMIC DRUGS

Question 2

C a d is the leading cause of death worldwide and its incidence is highly and people with

Answer 2

HYPERLIPIDEMIA

Question 3

These drugs are used to normalize high serum levels of cholesterol

Answer 3

BILE ACID SEQUESTRANTS

Question 4

Exert their effect in the intestine by binding into bile acids which contain a high level of cholesterol

Answer 4

BILE ACID SEQUESTRANTS

Question 5

Is also used to treat pruritus associated with partial biliary obstruction

Answer 5

CHOLESTYRAMINE

Question 6

this drug group increases the cell absorption of ldl by blocking the enzyme regulating the rate-limiting step in the synthesis of cholesterol

Answer 6

HMG CoA REDUCTASE INHIBITORS

Question 7

Block the completion of cholesterol synthesis in the body

Answer 7

HMG Coa reductase inhibitors

Question 8

Are indicated for patients with documented c a d to slow progression of the disease

Answer 8

PRAVASTATIN
LOVASTATIN
SIMVASTATIN

Question 9

Pravastatin lovastatin and simvastatin, together with this three agents _____ is used as prophylaxis for first myocardial infarction attack for patients with multiple risk factors for c a d

Answer 9

ATORVASTATIN

Question 10

Is the drug of choice for patients who have multiple risk factor or have already develop c a d

Answer 10

HMG-COA REDUCTASE INHIBITOR

Question 11

This class is well tolerated and is less expensive compared to other classes with the same therapeutic effect

Answer 11

HMG-

Question 12

Increased serum levels and resultant of hmg-coa reductase inhibitors

Answer 12

DIGOXIN
WARFARIN

Question 13

Atorvastatin can be given at

Answer 13

ANY HOUR OF THE DAY

Question 14

administered drug at bedtime to maximize effectiveness of the drugs because pic of cholesterol synthesis is from midnight to 5:00 a.m.

Answer 14

HMG COA REDUCTASE INHIBITOR

Question 15

Are one of the new class of drug approved to lower serum cholesterol levels

Answer 15

CHOLESTEROL ABSORPTION INHIBITOR

Question 16

Acting on the brush border of intestine,_____block the absorption of dietary cholesterol

Answer 16

CHOLESTEROL ABSORPTION INHIBITOR

Question 17

Increased toxicity of cholesterol absorption inhibitors

Answer 17

CYCLOSPORINE

Question 18

Increased risk for development of cholelithiasis

Answer 18

FIBRATES

Question 19

Altering the formation of platelet plug

Answer 19

ANTIPLATELET DRUG

Question 20

Altering interfering the clotting cascade and thrombin formation

Answer 20

ANTICOAGULANT DRUGS

Question 21

Altering the stimulating of the plasmin system to break down the formed class

Answer 21

THROMBOLYTIC AGENTS

Question 22

DisOrders that directly affect coagulation process

Answer 22

THROMBOEMBOLIC DISORDERS
HEMORRHAGIC DISORDERS

Question 23

Which involve overproduction of clots

Answer 23

THROMBOEMBOLIC DISORDERS

Question 24

Which is characterized by ineffective clotting process leading to excessive bleeding

Answer 24

HEMORRHAGIC DISORDERS

Question 25

Include medical conditions which involve overproduction of clots which result in to decrease blood flow and total vessel occlusion

Answer 25

THROMBOEMBOLIC DISORDERS

Question 26

Conditions under hemorrhagic disorders

Answer 26

HEMOPHILIA LIVER DISEASE BONE MARROW DISORDERS

Question 27

Characterized by genetic lack of clotting factors

Answer 27

HEMOPHILIA

Question 28

Characterized by non production of proteins and clotting factors necessary for clot formation

Answer 28

LIVER DISEASE

Question 29

Characterized by in sufficient quantity of platelets rendering them ineffective

Answer 29

BONE MARROW DISORDERS

Question 30

THROMBOEMBOLIC disorders manifestations include

Answer 30

Hypoxia Anoxia Necrosis

Question 31

This drug class exerts action by decreasing the responsiveness of platelets to stimuli that cause it to clump or aggregate

Answer 31

ANTIPLATELET AGENTS

Question 32

Blocks the production of platelets in the bone marrow

Answer 32

ANAGRELIDE

Question 33

Increase risk of bleeding if combined with another drug that affects blood clotting

Answer 33

ANTIPLATELET ANGENTS

Question 34

By interfering with clotting cascade and thrombin formation_____are able to interfere with the normal clotting process

Answer 34

ANTICOAGULANT

Question 35

Two new oral agents, directly inhibits thrombin and factor xa respectively

Answer 35

DABIGATRAN RIVAROXABAN

Question 36

Is used for prevention of blood clots in blood samples dialysis and venus tubing. It also does not enter breast milk so it is the anticoagulant of choice for lactating women

Answer 36

HEPARIN

Question 37

Block formation of thrombin from prothrombin

Answer 37

HEPARIN AND ANTITHROMBIN

Question 38

Antidote of heparin

Answer 38

PROTAMINE SULFATE

Question 39

Antidote of warfarin

Answer 39

VITAMIN K

Question 40

Blood test for warfarin

Answer 40

PROTHROMBIN TIME (PT) INTERNATIONAL NORMALIZED RATIO(INR)

Question 41

Blood test for heparin

Answer 41

WHITE BLOOD CLOTTING TIME ACTIVATED PARTIAL THROMBOPLASTIN TIME

Question 42

Promote clot resolution,the process of activating the plasmin system to break down the thrombus or clot that has been form

Answer 42

THROMBOLYTIC AGENTS

Question 43

Increased risk of bleeding when interaction with thrombolytic agents

Answer 43

ANTICOAGULANT AND ANTIPLATELET

Question 44

Evaluate the ability to clot

Answer 44

PT

Question 45

Blood thinning effect

Answer 45

PTT (60-70 SEC)

Question 46

How many seconds in APTT

Answer 46

30-40