Flashcards in Signal Transduction Deck (16):
what are intracellular signal?
signal that come from WITHIN the cell
what are intercellular signals?
responses to extracellular signals to coordinate metabolic activities
what are the 3 characteristics of G-protein coupled receptors (GPCR)?
1. extracellular ligand binding domain
2. 7 transmembrane spanning domains
3. intercellular G-protein activation domain
does G-protein stimulate or inhibit adenylyl cyclase?
either depending on the receptor (GPCR)
What are the three things that protein kinase A catalytic subunits can phosphorylate?
DNA binding proteins
what are the 2 enzymes that can stop the signal transduction pathway?
Calcium binds to ________ in the liver to activate enzymes and initiate metabolism?
what factors negatively affect insulin secretion?
decreased dietary fuels
what causes the secretion of epinephrine?
what factors positively affect insulin?
What is the enzyme that insulin activates?
What does tyrosine kinase phosphorylate?
Glucagon secretion is stimulated by?
Increasing epinephrine levels
Increasing amino acid levels
Glucagon is inhibited by?
Increasing glucose and insulin levels
What is the blood glucose level of hypoglycemia?
< or = 70 mg/dl