Skin cancers Flashcards Preview

Dermatology (also gross but true) > Skin cancers > Flashcards

Flashcards in Skin cancers Deck (30)
Loading flashcards...
1

What is the difference between solar lentigenes and freckles?

freckles fade in the winter and become inapparent in older ppl, whereas solar lentigines remain for life and become more prominent with aging

2

, benign, bright red to violaceous, domed vascular lesions. They generally appear first around age 30 and increase in number over the years

cherry angiomas

3

When should you do an excisional biopsy a lesion?

anytime a melanoma is suspected

4

the most serious form of skin cancer. accounts for majority of skin cancer deaths. it is a malignant tumor arising from melanocytes.

melanoma

5

Precursor lesions of melanoma

dysplastic nevi and giant hairy nevus

6

ABCs of melanoma

asymmetry, border irregularity, color, diameter, enlargement

7

refers to tumor thickness

breslow thickness

8

refers to anatomical descriptor (anatomical planes) of depth (I-V) of the malignant cells, “to dermis but not subq” etc

clark level

9

Most common subtype of melanoma that grows superficiallly and has good prognosis if caught early. Common btw 30-50yrs

superficial spreading

10

Subtype of melanoma that is invasive from the onset, poor prognosis. Any site, has rapid vertical growth and typically diagnosed at later stage. Most frequently diagnosed in 6th decade of life

nodular melanoma

11

Subtype of melanoma with tendency for head and neck. More common in elderly w/skin damage. Least aggressive

lentigo maligna

12

Occurs on palms, soles, subungual areas, and mucous membranes. Most common in people with darker skin types. Commonly diagnosed at advanced stage, poor prognosis

Acral Lentiginous Melanoma

13

Longitudinal pigmented streak that extends from proximal or lateral nail fold

Hutchinson's sign

14

Pigmented nevus surrounded by de-pigmented zone

halo nevus

15

Most common malignancy in humans, esp whites. Arise from basal layer of epidermis and is caused by DNA damage of keratinocytes

basal cell carcinoma

16

Typical appearance: translucent/pearly white papule with telangiectasias over the surface that slowly enlarges, with subsequent development of a central ulceration

basal cell carcinoma

17

Where do most basal cell carcinomas occur?

on the face

18

Surgical technique where thin layers of tumor tissue are removed and then examined microscopically

Moh's micrographic surgery

19

Arises from malignant proliferation of the keratinocytes of the epidermis. 2nd most common skin CA worldwide

squamous cell carcinoma

20

How does SCC often begin?

actinic keratosis

21

refers to carcinoma in situ, which is the next level following Actinic Keratosis. nonhealing, slowly enlarging erythematous patch with sharp but irregular outline

Bowen's Disease

22

flesh-colored nodule that enlarges and often undergoes ulceration and crusting (***lesion may be keratotic with a thickened surface)

invasive SCC

23

Treatment for Bowen's disease

Surgical excision of the lesion. Cryotherapy. 5-FU (Efudex) for 6 weeks under occlusion

24

Cutaneous tumor that presents as a dome-shaped nodule with a central keratin-filled crater. Develops on hair-bearing, sun-exposed skin. Middle-aged and elderly adults with fair complexions are most frequently affected

keratoacanthoma

25

Vascular tumor associated with infection with human herpesvirus 8 (HHV-8), also known as the KS-associated herpesvirus (KSHV)

Kaposi's Sarcoma

26

Type of Kaposi's not associated with immune deficiency

endemic or African

27

Ethnic groups typically affected by classic form of Kaposi's sarcoma

Older men of Mediterranean and Jewish origin

28

Other anatomical locations Kaposi's affects

oral cavity, gastrointestinal tract, and the respiratory tract

29

Presentation is papular, elliptical along skin tension lines with multiple colors and may be surrounded by yellow halo

kaposi's

30

Most important features to think about with derm lesion

change in size, color, and/or shape