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Flashcards in Pharm review Deck (26)
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1

First line for scalp fungal infections

griseofulvin

2

First line for nail fungal infections

terbinafine (Lamisil)

3

Duration of therapy for tinea capitis with griseofulvin

8 weeks

4

Administration instruction with griseofulvin

take w/fatty meal to increase absorption and lessen GI upset

5

T/F The smaller the particle size the greater the bioavailability

true

6

Pregnancy category of griseofulvin

X

7

For what allergy do you need to watch for potential cross reactivity when prescribing griseofulvin?

PCN

8

superior for the treatment of infections from Trichophyton species

terbinafine

9

superior for the treatment of infections due to Microsporum

griseofulvin

10

Labs needed prior to administration of terbinafine

AST/ALT and CBC

11

Minimum age needed to be prescribed terbinafine

at least 4 yrs

12

Treatment for failure of terbinafine for onychomycosis

itraconazole (Sporanox)

13

Black box warning of itraconazole (Sporanox) usually associated with IV administration

negative inotropic effects

14

Necessary before prescribing azole antifungals

drug interaction checker

15

First line therapy for the treatment of androgenic alopecia in men

finasteride (propecia)

16

What effect can finasteride have on PSA values?

can reduce them up to 50%. need to draw baseline before initiation of therapy and follow

17

When should you refer a patient on finasteride to urology?

if PSA increases while on medication

18

Treatment of severe, recalcitrant, nodular acne. only prescribed by dermatologist

Isotrentinoin (Accutane)

19

Baseline monitoring before initiation of Accutane

CBC, fasting lipid, LFTs. Repeat every 4 wks

20

How often should a woman on Accutane have a pregnancy test?

monthly during administartion and one month after discontuation of therapy

21

What abnormal lab results are necessary to discontinue Accutane therapy?

TG > 800 and LFTs 3X upper normal limit

22

Minimum age for use of topical calcineurin inhibitors

2 yrs

23

CI for topical calcineruin inhibitors

systemic immune suppressants and immunocompromised patients

24

Common side effect of protopic

skin burning at site of application

25

Patients present with some combination of arthralgia, myalgia, malaise, fever, rash, and/or serositis

drug induced lupus like syndrome

26

Treatment for drug induced lupus like syndrome

discontinuation and NSAIDs. if sx don't resolve within 4-8 wks hydroxychloroquine. if severe, systemic corticosteroids