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Dermatology (also gross but true) > Dermatopathology > Flashcards

Flashcards in Dermatopathology Deck (54)
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1

Epidermis cell type that can be categorized into the “stratum” layers. Predominant cell of the epidermis

keratinocytes

2

essential to the protective function of the skin and is the structural protein of hair and nails. produced by keratinocytes

keratin

3

Name the five layers of the keratiocytes

corneum, lucidum, granulosum, spinosum, germativum

4

Located at or in the basal layer. Pigment-synthesizing cells (produce melanin)

melenocytes

5

converts amino acid tyrosine to precursor of melanin. if you lack this enzyme you're albino.

tyrosinase

6

Increases production of melanin

UV rays

7

T/F Dark-skinned and light-skinned people have same amount of melanocytes

true

8

Least densely populated cells of the epidermis
Function as mechanoreceptors (touch receptors).

Merkel's cells

9

Scattered in the suprabasal layer of the epidermis. Immunologic cells responsible for recognizing foreign antigens harmful to the body

Langerhan's cells

10

Connective tissue layer separating the epidermis from the subcutaneous fat layer. Mostly composed of collagen

Dermis

11

Consists primarily of fat and connective tissues that lend support to the vascular and neural structures supplying the dermis and epidermis

subcutanesou tissue

12

Located over entire body surface, originate in dermis and open directly to the skin surface. transport sweat to body surface to regulate body temperature

Eccrine (merocrine) glands

13

located in deep dermal layer. Open through a hair follicle. sterile until mixed with bacteria

apocrine glands

14

Located over the entire skin surface except for palms, soles, and sides of feet. secrete sebum to lubricate hair/skin

sebaceous glands

15

determine hair color

melanocytes

16

causes goose bumps

arrector pili muscle

17

Circumscribed flat lesion < 1cm

macule

18

Flat lesion > 1cm

patch

19

Elevated solid lesion with variable color < 0.5cm. May become confluent and become a plaque

papule

20

Raised flat-topped superficial lesion where diameter is greater than the thickness (>0.5cm)(often formed by coalescence of papules)

plaque

21

Elevated lesion with a rounded surface (generally deeper and firmer than a papule)(0.5 – 1-2cm)

nodule

22

Large nodule (>1-2cm)

tumor

23

Somewhat irregular, transient swelling due to localized skin edema

wheal

24

Fluid-filled lesion up to 1cm

vesicle

25

Serous-filled lesion > 1cm

bulla

26

Circumscribed lesion filled with pus

pustule

27

Abnormal stratum corneum due to accumulation of, or increased shedding of keratinocytes

scales

28

Dried serum, pus, or blood (pt’s history reveals weeping, pus, or blood)

crusts

29

Partial loss of the epidermis (does not penetrate beneath dermal-epidermal border and therefore heals without scarring)

erosion

30

Full thickness loss of epidermis and at least some dermis, maybe all (heals with scarring)

ulcer