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Flashcards in Soft Tissue Tumors Deck (55)
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1

What is the basic definition of a soft tissue tumor

Mesenchymal proliferations that occur in the extraskeletal, nonepithelialized tissues of the body, excluding the viscera, coverings of the brain, and the lymphoreticular system.

2

What do we call a connective tissue neoplasm

A sarcoma.

3

Lipoma

Basically a benign adipose tumor

4

Are Lipomas usually slow growing or fast growing?

Usually slow growing

5

What is the ifference between a Lipoma and Liposarcoma?

THE HISTOLOGY. Histology is important in soft tissue tumors.
In a liposarcoma you will generally see atypical cells. For example, a lipoblast may be present. Basically a lipoblast is a weird cell with an atypical nucleus and lipid vesicles in the cytoplasm.

6

What is a nodular fascitis?

Rapidly growing, small benign , fibrous proliferationon the subcutis.

7

Nodular fascitis is most common in what age group?

Young adults

8

Nodular fascitis characteristically presents with what type of growth pattern?

Rapid

9

Nodular fascitis generally follows what?

Injury. It is thought to be a mesenchymal reaction to injury

10

Nodular fascitis most commonly seen in what areas of the body?

Arms. Particularly the flexxor surfaces of the arms

11

What does the histology look like in nodular fascitis?

Said to have a "loose tissue culture appearance"

12

What is Myositis Ossificans?

Reactive bone formation in the muscle as a result of injury. Entirely benign.

13

Mysositis Ossificans generally occurs in what area of the body>?

Lower limb

14

What is the key feature in differentiating myositis ossificans from a malignancy

Myositis ossificans shows a maturation pattern. The maturation pattern is woven bone at the periphery, but immature bone at the center. Malignancy does not show this pattern.

15

What are the two classifications of fibromatoses?

Superficial and deep.

16

Superficial fibromatoses appear where?

Hands, feet, penis

17

Which of the superficial fibromatoses is most common

The palmar one

18

Does fibromatoses tend to affect one sex more than the other?

Yes. Male predominance

19

Palmar fibromatoses generally appear on one side only?

FALSE. Generally bilateral

20

Plantar fibromatoses

Generally appear in a younger age group but are also bilateral in most cases

21

Penile fibromatoses

Rare. Generally accompany other superficial fibromatoses

22

What is infantile digital fibromatoses

superficial fibromatoses that appear in the digits of young children and are characterized by inclusion like condensations of cytoplasmic actin.

23

What is Dupuytrens's contracture

It is a condition of fixed flexion of the hand where the fingers bend towards the palm and cannot extend.

24

What fingers are most commonly affected?

Ring and pinky

25

Deep Fibromatoses

Aggressive, Rare, More common in females until after their 20's.

26

Deep fibromatoses generally occur where in peds and in whom?

Extra-abdominal, females

27

Deep fibromatoses generally appear where pts in their late 20's and who is generally affected?

Abdominal wall, females typically affected still. Past this, however, no sex predisposition and tumors do not occur in the abdomen as often.

28

Does radiation work on these tumors?

Nope. They are not malignant....do not divide quickly.

29

Definition of a fibrosarcoma

Tumor of mesenchymal origin that is composed of MALIGNANT FIBROBLASTS in a collagen background.q

30

Where may fibrosarcomas develop?

THey may be soft tissue masses or bone tumors.

Generally develop in the lower extremities (femur and Tibia if in bone, thigh and posterior knee if in soft tissue)