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Flashcards in Stroke Deck (17):
1

goals of treatment ICH

contain and limit bleeding
remove blood
manage complications (ICP, decrease cerebral perfusion)
control causative factor

2

contraindicated drugs ICH

thrombolytics, anticoagulants, warfarin, antiplatelet drugs

3

goals of treatment SAH

quickly identify cause and prevent rebleeding
prevent brain damage

4

this is a dihydropyridine CCB that reduces incidence and severity of ischemic defects that can occur after a SAH

nimodipine

5

this drug is metabolized by CYP450 3A4 enzymes

nimodipine

6

causes of ischemic stroke

thrombosis
embolism
systemic hypoperfusion

7

rule this out prior to initiation of therapy for ischemic stroke

hemorrhagic stroke

8

only FDA approved therapy for treatment of acute ischemic stroke

rtPA, alteplase

9

onset of symptoms to administration of this drug must be less than 3 hours

rtPA

10

contraindications include prior ICH, sustained BP >185/110, low platelets, low HCT, recent major surgery, GI bleed, MI, stroke, head trauma, coma

rtPA

11

BP should be stabilized at <180/105 and maintained before treating with

rtPA

12

this drug is found to increase morbidity and mortality secondary to ICH

streptokinase

13

goals of therapy ischemic stroke

reduce progression
reduce risk of recurrent thromboembolism
prevent DVT/PE

14

only antiplatelet agent evaluated for the treatment of acute ischemic stroke

aspirin

15

DVT/PE prophylaxis acute ischemic stroke

low dose SQ heparin or LMWH

16

DVT/PE prophylaxis ICH

intermittent pneumatic compression- low dose SQ heparin

17

drug classes for recurrent stroke prevention

thiazides
ACEI