Thurs Wk 5 Mixed 1 Flashcards

1
Q

SRY gene codes for __ to develop testes
this leads to sertoli cells producing __ to cause mullerian involution
also release __ to concentrate T in seminferous tubules and allow for spermatogenesis

Fick Principle of CO is __ over AV O2 content difference
blood O2 content is O2binding capacity x __ + dissolved O2

Ischemic bowel undergoes __ prodxn, w resulting AGAP MA
this stimulates renal ammoniogenesis by metabolizing __ into ammonium/bicarb
bicarb is __ to buffer acid in blood
half of acid is secreted in urine as __ and other as Phosphate
thus, inc __ prodxn is seen in chronic acidosis

Histidine becomes __

A

Testes determining factor
AMH
ABG

Rate of O2 consumption
saturation%

lactate
glutamine
reabsorbed
ammonium
ammonium

HISTAMINE

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2
Q

interior thyroid artery helps to supply the __ gland
found deep to __ vein, vagus nerve, and CCA
very close to __ nerve
RLN loops below __ on left and subclavian artery on right
can be damaged upon attempted __
SLN runs close to __

can use M__ to prevent ulcers w NSAIDs

Osmium tetroxide stains fat __
accumulation of __ on fat emboli thought to cause thrombocytopenia
activation of LPL and oleic acid thought to aid in __ dysfxn
WRIGHT STAIN IS FOR __

arterial puncture above __ ligament inc risk for retroperitoneal hemorrhage
cannot be controlled via __ thus pt has hypoTN, flank pain and dec hemoglobin

Right paracolic gutter may have fluid from A/G
hemorrhage into thigh muscle would result in __ syndrome

A
thyroid
Internal jugular
RLN
aortic arch
ligation
Superior laryngeal artery

misoprostal

black
platelets
neuro
PLATELETS

inguinal
compression

appendix, gall bladder
compartment

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3
Q

SSSS occurs due to __ exotoxin
see Nikolsky sign, epidermal ___ and fever w rash
blister only occurs in superficial __ due to exfoliatin acting as protease

__ is area of LN w t cells and dendritic cells
located bw follicles and __
follicles are in __ and house B cells
medullary cords have / cells and macros
medullary sinuses have reticular cells and __
subcapsular sinus directly communicates w __ lymph vessels
corticals sinuses drain __ sinus and connect to efferent lymph channel

ABP >150 causes in cerebral __ and pressure
ABP <50 results in __
CO2 causes __

A

exfoliatin
necrolysis
epidermis

paracortex
medulla
cortex
B/plasma cells
macros
affarent
medullary

perfusion
hypoperfusion
VASODILATION

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4
Q

think __ ED w rapid onset
should have __ erection, unlike those w neuro/vasc problems
important meds include SSRI And B/M/C

__ bias is RF leads to extensive diagnostic investiation and thus dz are more likely to be found

Dandy walker is absence of __ w dilation of 4th ventricle and posterior fossa enlargement
sx include developmental delay, poor muscle __ and NCH w irritability/vomiting

ACt2 is downward displacement of __ into foramen magnum
pt has spinal __ as well

GGP is not found in __ thus helps to localize ALP to liver

adenocarcinomas may release __ tumor products resulting in hypercoag

A

psychogenic
nocturnal
BB, methyldopa, clonidine

cerebellar vermis
coordination
non communicating hydrocephalus

vermis
myelomeningocele

bone

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5
Q

__ is facultative intracelular, gram positive tumbling rod
tx w __
must have __ as it is intracellular

Listeria/MRSA/Enterococci are resistant to __ due to PBP

__ is needed for transamination/decarbox of AA
transamination occurs bw AA and __

Bacillus anthracis has __ capsule
__ carries other toxins
Protective antigen translocates factors to _
__ factor is calmodulin dependent AC to inc cAMP
leads to __ w/in cells to suppress PMN/macros

Pertussis has _ toxin to cause edema/phagocyte probs

A

listeria
ampicillin
CMI response

cephalosporins

VB6
a keto acid

d glutamic acid
exotoxin
cytosol
edema
water

AC

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6
Q

__ factor of B anthracis inhibits PK signaling causing apoptosis/disruption
like C botulinum/dificile, it exists as __

Pertussis toxin downregulates _ via ADP ribosylation to inc cAMP

Pyrogenic exotoxin of Strep pyo acts as __

pt w __ deficiency can have MC excess due to inc 11B deoxycorticosterone

17OHPROGESTERONE IS ALWAYS __ in 21 hydroxyalse def

invasive mole has trophoblast that is diffusely _ w myometrial invasion
villi are diffusely enlarged and __
Choriocarcinoma is malignant tumor of __
see bleeding, high bHCG and hematogenous spread to ___
see in / w out villi

A

Lethal
spore

Gi

superantigen

HIGH

hyperplastic
edematous
trophoblast
lungs
c/s
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7
Q

preg has inc __ to accomodate blood loss
GFR/renal circ __ due to relaxin from BHCG
thus, urine volume is __ w dec bladder capacity
thus, anything that inc __ cause rise above EUS and result in urination

Stress incont has dec urethral sphincter __ or urethral hypermobility
both due to relaxing __ musces/urethral tone

MEDIAL LYMPHATIC SYSTEM OF LEG __ POPLITEAL LN
LATERAL LESIONS FOUND IN BOTH __/__ LN

benzos can stop spasticity from __ disorders
avoid w A, B, N, antihistamines

C/R/F/N are H2 blockers
L, F, C, D

A

plasma volume
inc
increased
intraabdominal pressure

tone
pelvic floor

bypass
popliteal/inguinal

UMN
alcohol, barbs, narcotics

cimetidine, ranitidine, famotidine, nizatidine

Loratadine, fenofatadine, cetirazine, desloratadine

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8
Q

unfractionated/LMH bind to __ to cause it to change shape and inhibit Factor Xa

blood supply to proximal ureter comes from __ artery
blood supply of distal ureter is __ artery
in transplant, donor renal artery anastamoses to recipient __ artery, thus strong blood flow is established
lack of anastamoses to distal ureter leads to __ and leaky urine

circulation to middle ureter is variable w __

After MI, tx pt w __/__

intense pruritis is hallmark of \_\_
should be located in \_\_ areas
look for weeping, crusted \_\_ plaques
due to mutations in F\_\_ inmpairing fxn of skin
look for high serum \_\_/\_\_
A

AT3

renal
superior vesical
renal
ischemia

anastamoses

BB, ACEI

atopic dermatitis
flexural
red
filaggrin
IgE/eosinophilia
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9
Q

neurons in area of ischemic damage show __ w/in 24-48 hrs
in 3-5 days, __ appear and accumulate lipids from phagocytosis of myelin
ASTROCYTES COME AROUND __ after event

Azoles inhibit __ of lanosterol into ergosterol and p450 consequently

Aortic dissection due to tear in aortic __
as it spreads, it can compress __ leading to BP discrepancy w blood passes through media
major RF is __ due to medial hypertrophy of vaso vasorum and dec blood flow to media and inc stiffness

tertiary syphillis aortitis is due to obliterative __ in VV

Costochondritis involves costal cartilge at / jxns

A

PMN
microglia
2w

lanosterol

intima
arterial branches
HTN

endarteritis

costochondral, costosternal

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10
Q

SNS fibers contract __ and sense a full bladder
PNS fibers __ IUS

continuous leakage and incomplete emptying is __ incontinence

Bromocritpine/cabergoline are __ derivatives of Dopamine
Pramipexole/ropinirole are __ derivatives of dopamine

A__ may have anticholingeric effects to reduce tremors

RBC precursors in liver/spleen indicates __ hematopoeisis
usually seen in __
progenitor cells of bone marrow expand and thin bone __ leading to dec bone growth w many fractures
also see M__ overgrowth and frontal bossing/chipmunk faces

A

IUS
relax

overflow

ergot
nonergot

amantadine

extramedullary
B thalasemmia
cortex
maxillary

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