Thurs Wk 6 Mixed 3 Flashcards

1
Q

always think __ in male pt w UTI after cystoscopy

typical conduit of HAV from food is __

it pt w 1 testis, mass of __ cells is significantly reduced
thus __ is high due low inhibin
however, __ prodxn is normal despite dec Leydig

Cardiac tamponade collapses the __ w ventricular expansion

pulsus alternans seen in severe __ dysfxn
electrical alternans is __ w varied QRS complex amplitude due to swinging of heart

some panic attacks must be __
worry about __ attacks

A

Enterococcus

shellfish

Sertoli
FSH
testosterone

RA

LV systolic
Pericardial tamponade

spontaneous
future

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2
Q

dystonic rxns to AP are __
due to __ of NS pathway
leads to excess __ activity, extrapyramidal SE develop
thus, tx w B or H1 antag D

G6PD fxns in __ path of PPP
NADPH useful in __ stress
or __ biosynthesis of FA, cholesterol, steroids, p450
phagocytic cells w __

M and M can also cause MHA
this is not __ in etiology

PSGN is due to __ HS rxn w immune complex deposition

inspissated dehydrated mass at distal ileum is __ dx
very specfic for __
death occurs due to _. _. _ in these pts
squirt sign is __

Hirschprung dz has obstruction at __ colon
squirt sign is __
pts die from __ w diarrhea, ab pain, fever

A

ACUTE
D2 antagonism
M1 cholingergic
Benztropine, diphenhydramine

OXIDATIVE
oxidative, reductive
respiratory burst

Malignant HTN, metastatic carcinoma
Autoimmune

type 3

Meconium ileus
Cystic fibrosis
PNA, bronchiectasis, Cor pulmonale
negative

rectosigmoid
positive
enterocolitis

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3
Q

Anatomic snuff box bounded by __ on top
__ and __ on bottom
scaphoid and __ form floor
dorsal _ branch of radial artery supplies bone, which is at high risk for _ and nonunion

Fracture of lunate may lead to __

FN calculation

Strep pneumo meningitis usually occurs following __
common causes of meningitis in babies: S, E, L

BPH has hyperplasia in P/T zones
pt has __ w probs voiding/storing urine
later, incomplete __ occurs w overflow incontinence
Hydrostatic force must rise, leading to __ of bladder wall musculature
proximal segments __ w pressure atrophy/CKD

A
EPL
EPB, APL
trapezium
scaphoid
avascular necrosis

CTS

1-sensitivity X number w the disease

infection
GBS, e coli, listeria

periurethral, transitional
BOO
emptying
hypertrophy
dilate
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4
Q

viral tropism depends on ability of viral __ to bind host cell surface receptor glycoprotein
W enveloped viruses, __ protein is prevented from cel contact

influenza has __ to cleave short primers for viral RNA polymerase called cap snatching

AT2 is formed in small __ vessels by ACE
thus levels are highest in __
if central volume is __, ADH is higher

duration of __ indicates AR severity
worse causes a __ murmur w mild only causing early diastolic murmur
due to aortic __ or BAV

HCM assc w __ murmur

use P__ if pt is on drug that inhibits p450 as it is not metabolized by this enzyme

A

surface glycoprotein
nucleocapsid

endonuclease

pulmonary
PULM VEINS
low

murmur
holodiastolic
root dilation

MR

PRAVASTATIN

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5
Q

HIV protease inhibs are __ of p450
along w I/E

Lobar PNA
__ day 0-2 w PMN releasing cytokines to inc permeability
immune cells migrate and __ accumulate w proteinaceos fluid in alveoli
lobe appears heavy and _
_ hepatization day 2-4
fluid forms __ strands w PMN/RBC
lobe looks __ like and is firm
_ hepatization occurs by 7 days
red cells __ w inc leuks make lung look red
__ replace PMN and start repair
Resolution as macros secrete __ that liquefy fibrinous exudate to be taken up by macros

__ is PNA in term bronchioles w patchy consolidation
__ is infection of interstitial tissue

A

inhibitors
isonizid/Erythromycin

congestion
RBC
red
red hepatization
fibrin
liver
gray
disintegrate
macros
digestive enzymes

bronchopneumonia
interstitial PNA

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6
Q

__ is homodimeric Ca binding protein like calmodulin
marker of __ derivation as well as Langerhans/Dendritic cells

VSD usually heard __ birth as PVR falls and LtR shunting occurs
ToF sx depend on __

Dohle bodies are basophilic peripheral granules in __
occurs in __ rxn w infection/hemorrhage, tumor, hemolysis
can inc marrow PMN __ like myelocytes
may also seen PMN w toxic _ or cytoplasmic vacuoles

MAJORITY OF WATER/SOLUTES IS REABSORBED IN __

A

S100
NCC

after
degree of RVOT

neutrophils
LEUKEMOID RXN w high leuk ALP
PRECURSORS
granules

PROXIMAL CONVULETED TUBULE

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7
Q

Cholinesterase inhibs Tertiary amines include P, G, D, R
these cross BBB for / sx
Quaternary amines N, E, P do not cross BBB

Anticholinergic tox
Hot due to lack of __ and heat dissipation
dry due to dec glandular __ and smooth muscle contractin
flushed due to superficial _
blind w paralysis of /
penetrates BBB to affect __
urinary retention due to dec intestinal __ contraction
dec / contraction
fast due to dec _ tone at SA node

ischemic myocardium has __ than normal membrane potential, thus slower recovery of Na channels
thus use Class 1B antiarrhythmics for __ ventricular arrhythmias

A

physostigmine, donezepil, galantamine, rivastigmine
Central/peripheral
Neostigmine, Edrophonium, pyridostigmine

sweating
secretions
VD
ciliary body/iris sphincter
CNS
smooth muscle
detrusor/IUS
vagal

higher
ischemia induced

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8
Q

Wilson dz has reduced formtion of __ thus dec secretion of copper
causes damage via __
look for damage to __ and psych abnorms

__ releases EPO to stimulate receptors in the bone marrow

most gastric ulcers form on \_\_
parietal cells secrete \_\_ in body
glands in antrum secrete _
at the transition \_\_ colonizes
can erode _/_ arteries

maintenance stage of ATN leads to high __ volume w edema and pulm congest
__ that can lead to peaked T waves/arrhythmia
retention of H/anions leads to __
dec Na/Ca/phos/Mg w high urinary __ and FeNa

in recoery stage, large volume __ urine is released
leads to _ K, Mg, Ca

A

ceruloplasmin
Free radicals
BASAL GANGLIA

EPO

lesser curvature
HCl
gastrin
H pylori
right/left gastric

Extracellular fluid
hyperkalemia
AGAP MA
Na

hypotonic
low

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9
Q

Pt w Fragile X syndrome has facial abnorms and __
meiosis in oocytes can cause __ w DNA hypermethylation
this __ FMR1, stopping prodxn of FMR protein that inhibits neural development

hemolytic anemia, hypercoag, and Pancytopenia is __
mutation in __ cannot attach GPI to CD59/CD55
these proteins __ complement and prevent overactivity
leads to __ hemolysis at night due to low pH
thromboses due to release of T/P factors

dec maximal effect w two drugs indicates __ inhibitor
example is NE and P__ that is irreversible antag at A1/A2 receptors
P_ is competitive inhibitor
graph would show inc __ but normal effiacy

Labetalol is __ antag of A1/B receptors

A

NEUROPSYCH SX
trinucleotide expansion
downregulates

PNH
PIGA
inactivate
complement mediated
thrombin, procoag

NONCOMPETITIVE
PHENOXYBENZAMINE
PHENTOLAMINE
Km

competitive

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10
Q

HCL due to __ infiltrate bone marrow w fibrosis and pancytopenia
see dry tap w massive __
look for positive __ on flow cytometry

AML DOES NOT CAUSE __
ringed sideroblasts can be seen in __ syndrome

EBV is most common cause of general __

think __ w epigastric calcifications and hx of alcohol
due to proteinaceous secretions from __ that plug pancreas
see __ insuffiency w malabsorption

DIC due to intravascular __ w compensatory thrombolysis and consumptive coagulopathy

ITP smear has isolated __

A

B cell
SPLENOMEGALY
TRAP

splenomegaly
myelodysplastic

LAD

chronic pancreatitis
alcohol
EXOCRINE

thrombosis

THROMBOCYTOPENIA

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11
Q

IgG warm AIHA due to / or alphamethyldopa

nitroprusside overdose/kidney failure leads to __ toxicity
inhibits _ to stop OP
see seizure, AMS, LA and __ blood
Cyanide normally metabolized by __ to transfer sulfur molecule to form thiocyante
becomes __ if overwhelmed

use __ as antidote to provide sulfur group for rhodanse
H__ directly binds cyanide
S__ induces Methemogobinemia formation

A

SLE, CLL

cyanide
cytochrome C
bright red venous
rhodanse
toxic

sodium Thiosulfate
hydroxycobalamin
Sodium nitrate

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