Tissue injury and repair Flashcards Preview

Pathology (m) > Tissue injury and repair > Flashcards

Flashcards in Tissue injury and repair Deck (15):
1

Increased demand and stimulation can lead to...

Hypertrophy & hyperplasia
E.g. left ventricular hypertrophy

2

Decreased nutrition and stimulation can lead to...

Atrophy
E.g. muscle shrinkage

3

Chronic irritation can lead to...

Metplasia
E.g. oesphogus

4

Tissue regeneration is...

Complete reconstitution

5

Tissue repair is...

Combo of regeneration and scar formation

6

Examples of regeneration...

Superficial skin wounds
Liver generation after partial hepatectomy

7

Examples of repair...

Myocardium infarc
Deep excisional wounds

8

Examples of fibrosis (tissue scar)...

Chronic inflam diseases (cirrhosis)

9

Examples of true regeneration (limited)...

Bone after fracture
Epithelium following superficial injury

10

Local factors that affect wound healing are...

Size
Location
Type

11

What can delay wound healing?

Infections
Mechanical forces
Foreign bodies

12

Systemic factors that affect healing are...

Nutritional status
Metabolic status
Circulatory/vascular status
Hormones

13

Where normal tissue architecture cannot be restored, it is mostly replaced by...

Fibrous tissue

14

Name complications of tissue repair...

Contractures
Excessive repair
Deficient scar formation (wound dehiscence)

15

What is the sequence of healing?

Inflam
Angiogenesis
Migration and increase amount of parenchymal cells and fibroblasts
Scar formation
Connective tissue remodelling