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Flashcards in Topical Skin Therapeutics Deck (20)
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1

Name a common mild topical steroid

Hydrocortisone 1%

2

Capsaicin is useful in the treatment of what?

Pruritis

3

Why is capsaicin useful in the treatment of pruritis?

Depletes substance P at nerve endings and reduces the neurotransmission which would normally aid pruritis

4

What is commonly used to treat ringworm (dermatophytes)?

Clotrimazole

Terbinafine

5

In which condition are steroids generally avoided, or used with extreme caution?

Roseacea

(can cause steroid-induced rosacea)

6

What is the main advnatge for topical treatment?

Reduces systemic effects

7

Topical corticosteroids have which 3 main effects?

  1. Anti-inflammatory
  2. Antiproliferative
  3. Vasoconstrictive

8

Which topical treatment is used in every case of psoriasis?

Emollient

9

Besides emollients, which other treatments can be used for psoriasis?

Coal tar

Vitamin D analogue

Keratolytic

Topical steroids

Dithranol

10

What is nystatin?

Topical antifungal

11

How can candida be treated?

Nystatin

Clotrimazole

Oral fluconazole

12

What is tachyphylaxis?

Decrease in response to anti-inflammatory effects

13

Name a potent steroid

Mometasone

14

When thin skin becomes a problem with steroid use, what is an alternative class of drugs?

Calicneurin inhibitors

(tacrolimus or pimecrolimus)

15

How do calcineurin inhibitors work?

Suppress lymphocyte activation

16

Which dermatological condition are calcineurin inhibitors typically used for?

Eczema

17

Which side effect do steroids have which calcineurin inhibitors avoid?

Thin skin

18

What are the side effects of calcineurin inhibitors?

Burning sensation on application is commonly reported

Increase risk of cutaneous infection

Skin cancer (with chronic use)

19

Which effective treatment for psoriasis is irritant and will stain normal skin?

Dithranol

20

Which steps can ensure emollients are applied to ensure the best results?

Apply after bathing

Apply at least once per day

Apply in the direction of hair growth

Use a spoon or spatula to remove the emollient when applying