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Flashcards in Clinical Cases of Rash Deck (20)
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1

Which condition is characterised by damage and infiltration of the basal layer of the epidermis?

Lichenoid eruptions

2

Where on the body does pemphigus vulgaris commonly affect?

Scalp, face, axillae and groin

3

Fine lace-like pattern on the surface of papules and on the buccal mucosa describes which characteristic sign?

Wickham's striae

4

Which age group does bullous pemphigoid affect?

Elderly

5

What may present in the early stages of bullous pemphigoid?

Urticated itchy patches

6

What is the main difference between rosacea and acne?

Rosacea does not involve comedones

7

How is bullous pemphigoid treated?

Systemic steroids

(potentially oral tetraycline as adjunct)

8

In which condition are steroids generally avoided as part of treatment?

Rosacea

9

What will a skin biopsy show in a patient with pemphigus vulgaris?

Acantholysis

10

Which investigations will be undertaken for either bullous pemphigoid or pemphigus vulgaris?

Indirect immunofluorescence

Skin biopsy (with direct immunofluorescence) - to detect IgG at the relevant skin boundary

11

In which condition (pemphigus or pemphigoid) is mucosal involvement very common?

Pemphigus vulgaris

(rare in pemphigoid)

12

When treating psoriasis, which medication is given alongside UVA treatment to make the skin temporarily sensitive to the UVA radiation?

Psoralen

13

Which type of psoriasis is most common in young adults?

Guttate

14

What is the preferred treatment for psoriasis?

Vitamin D analogues such as calcipotriol or calcitriol

15

Which type of psoriasis can develop in acral regions and has acute presentation?

Palmoplantar

16

How long must antibiotics be used before they can be considered ineffective in a patient with acne?

6 months

17

Which acne treatment is keratolytic and antibacterial?

Benzoyl peroxide

18

In very severe cases which treatment may be utilised?

Isotretinoin

19

Which condition generally affects the volar wrists, forearms, shins and ankles?

Lichen planus

20

What is described by

"The fact that psoriasis can develop in areas of trauma on the skin which are otherwise healthy"

Koebner phenomenon