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Flashcards in Microbiology and the Skin Deck (44)
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1

Which organism is responsible for Staphylococcal Scalded Skin Syndrome (SSSS)?

S. aureus

2

When Staphylococcal Scalded Skin Syndrome occurs in a newborn, what is the name of the condition?

Ritter's disease of the newborn

3

Which type of patient is most at risk of Staphylococcal Scalded Skin Syndrome?

  1. Children < 6 years
  2. Immunosuppressed
  3. Renal failure

4

How does Staphylococcal Scalded Skin Syndrome present?

  1. Widespread formation of fluid filled blisters
  2. Blisters are thin walled and Nikolsky's sign +ve
  3. Widespread painful erythroderma

5

Which areas of the skin are most affected by Staphylococcal Scalded Skin Syndrome?

  1. Face
  2. Perineal region
  3. Areas where skin rubs together

6

How is Staphylococcal Scalded Skin Syndrome different from Toxic epidermal necrolysis?

Staphylococcal Scalded Skin Syndrome spares the mucous membranes

7

What is the antibiotic of choice against S. aureus?

Flucloxicillin

8

How many types of necrotising fasciitis exist?

2

9

What causes type 1 necrotising fasciitis?

Aerobic or anaerobic bacteria

10

When is type 1 necrotising fasciitis most frequently seen?

Post surgery

11

What causes type 2 necrotising fasciitis?

Group A streptococcal species

(e.g. Strep. pyogenes)

12

Why is Nikolsky's sign negative in necrotising fasciitis?

Infection spreads into the subcutis and underlying muscle tissue

13

What is a classic sign of necrotising fasciitis on plain X-ray?

Crepitus

(gas produced by bacteria)

14

Why is surgery the only option for necrotising fasciitis?

  1. Treatment is required quickly and surgical debridement is necessary
  2. There is poor vascualr network due to tissue destruction for antibiotics will not be able to penetrate

(IV antibiotics will still be given with surgery, but never alone)

15

What are the treatments for candida intertrigo?

  1. Clotrimazole cream
  2. Nystatin
  3. Oral fluconazole

16

What is candida intertrigo?

Candidal fungal infection often seen in skin folds

(e.g. under breasts, groin areas, abdominal folds, nappy areas)

17

Which microorganism causes toxic shock syndrome?

S. aureus

18

Why is Toxic shock syndrome associated with young women?

It is associated with the use of high absorbancy tampon use

19

Which type of rash is associated with toxic shock syndrome?

Diffuse scarlatiniform rash which later desquamates

(clearly present on palms and soles)

20

Where does the rash associted with toxic shock syndrome normally manifest?

  1. Palms and soles
  2. Accentuation in skin folds
  3. Inguinal folds/perineal area

21

What are the main symptoms of toxic shock syndrome?

  1. Hypotension
  2. Shock
  3. Hyperaemia of mucous membranes
  4. Pharyngitis
  5. Strawberry tongue
  6. Skin/muscle tenderness
  7. Oedema of hands/feet

22

What is dermatophyte infection?

Fungal infection causing ringworm

23

By which three methods is dermatophyte infection diagnosed?

  1. Clinical appearance
  2. Skin scaping s and culture
  3. Woods light

24

Which group of Streptococcus is associated with neonatal meningitis?

B

25

What is Mucormycosis?

Any fungal infection in the order Murcorales

Characterised by hyphae growing in and around blood vessels

 

26

In which patients may Mucormycosis be life threatening?

  1. Diabetic
  2. Immunocompromised

27

What do dermatophytes require for growth?

Keratin

28

How is an infection with sarcoptes scabiei treated?

  1. Benzyl benzoate (adults, not children)
  2. Malathion lotion (applied overnight and washed off)

29

Strep. pyogenes can be treated with which antibiotics?

Flucloxicillin or penicillin

30

In diabetic patients with severe leg ulcers, what treatment should be given for anaerobic cover?

Metronidazole