U.S Health final exam- infectious disease Flashcards

(52 cards)

1
Q

wearing long sleeves can break the chain of infection at

A

C
Port of entry

a mosquito cannot get in

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2
Q

Ten Greatest Pubic Health Achievements

A

Ten Great Public Health Achievements — Worldwide, 2001-2010
Reductions in Child Mortality
Vaccine-Preventable Diseases
Access to Safe Water and Sanitation
Malaria Prevention and Control
Prevention and Control of HIV/AIDS
Tuberculosis Control
Control of Neglected Tropical Diseases
Tobacco Control
Increased Awareness and Response for Improving Global Road Safety
Improved Preparedness and Response to Global Health Threats

Ten Great Public Health Achievements – United States, 2001-2010
Vaccine-Preventable Diseases
Prevention and Control of Infectious Diseases
Tobacco Control
Maternal and Infant Health
Motor Vehicle Safety
Cardiovascular Disease Prevention
Occupational Safety
Cancer Prevention
Childhood Lead Poisoning Prevention
Public Health Preparedness and Response

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3
Q

Deadly infectious diseases

how has infectious disease impacted people

what are some examples of outbreaks

A

Throughout time many infectious diseases have killed millions of people

Bubonic plague (“Black Death”)-1/3 of European population
Small Pox- has been eradicated
Cholera
Tuberculosis (TB)
Typhoid
Yellow fever

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4
Q

Public Health measures

A

Purification of water
Proper disposal of sewage
Pasteurization of milk
Immunizations
Improved nutrition
Personal Hygiene
Discovery of antibiotics

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5
Q

Infectious Agents

A

Bacteria:
Tuberculosis, cholera, typhoid, tetanus, diphtheria, dysentery, syphilis, streptococci, staphylococci

Viruses:
Smallpox, poliomyelitis, hepatitis, measles, rabies, AIDS, yellow fever

Parasites:
Malaria, cryptosporidiosis, giardiasis, roundworms,
, hookworms, pinworms

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6
Q

Diseases caused by viruses

A

Smallpox
Yellow fever
Polio
Hepatitis

Influenza
AIDS
Common cold
Measles

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7
Q

Diseases caused by protozoa

A

Malaria
Cryptosporidiosis
Giardiasis
Pinworm

Tapeworm
Hookworm
Roundworm

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8
Q

How can infectious diseases be transmitted?

A

Person-to-person
Via respiratory secretions
Sexually transmitted

Water
Fecal-oral route

Food

Vectors
Mosquitoes, rats, bats

Fomites- touching contaminated objects and putting hands to face, nose or eyes

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9
Q

Chain of Infection Links
link 1

A

Link 1- Pathogen: Bacteria, virus, parasite that cause illness in humans

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10
Q

Chain of Infection Links
link 2

A

Link 2: Reservoir: this is the place where the pathogen can live and multiply.

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11
Q

Chain of Infection Links
link 3

A

Link 3: Method of transmission: this is the way a pathogen can travel from one host to another

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12
Q

Chain of Infection Links
link 4

A

Link 4: Susceptible host: One that can be readily infected.
- Not all hosts are susceptible-they have immunity to the pathogen
- The support of the pathogen’s life and its reproduction depends on the degree of the host’s resistance

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13
Q

Port of exit:
how can an infectious microorganism leave the body

A

How an infectious microorganism may leave the body
- Secretions of mucus
- Blood
- saliva
- Other fluids

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14
Q

Port of entry

what is ths

what are the 4 methods of entry

A

: The route through which the pathogen enters a new host

4 methods of entry:
Respiratory system (inhalation)

Gastrointestinal (ingestion of pathogen)

Urinary and reproductive tracts (sexual contact)

Breaks in protective skin barrier

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15
Q

How to interrupt the chain of infection:

what is link 1 and how can it be interrupted

A

The most vulnerable part of the chain is the point where public health measures can interrupt to prevent the spread of disease!

Pathogen identification
- Proper identification of infectious agent and appropriate treatment
- Correct antibiotic for treatment of infectious disease

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16
Q

How to interrupt the chain of infection:
Eliminate the reservoir

how can we prevent the spread of food-borne pathogens

what can prevent water-borne pathogens

what two things are necessary

A

By maintaining proper hygiene you can prevent spread of food-borne pathogens

Having adequate water and sewage treatment can prevent spread of water-borne pathogens

Disinfection and sanitation

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17
Q

How to interrupt the chain of infection:
Prevent means of transmission

A

Direct or indirect contact can be altered by:
- Proper hand washing
- Isolation of those infected (quarantine/isolation)
- Use of condoms
- Not working when contagious
- Wearing masks

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18
Q

How to interrupt the chain of infection
Susceptible Host:

A

Resistance of host can be increased by immunization

Protect high-risk patients by wearing a mask with :
- Cancer patients
- AIDS
- Transplant patients
- Infant and elderly
- Proper disposal of needles/sharps

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19
Q

How to interrupt the chain of infection
Ports of entry

what can you wear

what should you cover

what should you wahs before eating

what else should you wear

A

Wear long sleeve shirts to prevent malaria carrying mosquito from biting (break protective skin barrier)

Cover open wounds

Wash hands before eating (avoid pathogen entering via GI system)

Wearing PPE

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20
Q

How to interrupt the chain of infection
Ports of exit

what should you always wash hands with

what else should you wear

what should you properly dispose of

what etiquette should you have

A

Hands: always wash hands with soap and water after handling potentially contaminated material

PPE such as gloves and masks if respiratory droplets are a concern

Proper trash and waste disposal

Respiratory etiquette

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21
Q

What are some ways to break the chain of infection for COVID-19?

A

Wearing a mask

Social distancing

Hand hygiene

Cover coughs & sneezes

Clean & disinfect

Monitor daily health

are these all transmission?

22
Q

Public Health Measures
Epidemiological Surveillance:

what do PH officials always do and what will they do if necessary

what is contact tracing

what happens after contact tracing??

A

Epidemiological Surveillance:
- Public health officials watch for diseases. If necessary they will interrupt the chain of infections

  • Contact tracing: Identification and diagnosis of persons who may have come into contact with an infected person.

When is contact tracing routinely used??
- Immunization and treatment of identified patients to prevent further spread
- Quarantine/isolation if necessary

23
Q

Eradication

when is eradiation possible

what disease was eradicated

what disease is eradiacted from in the western hemisphere but where are there still cases

what disease has had recent outbreaks in the U.S

A

Eradication is possible if there is no non-human reservoir and if a vaccine exists

Smallpox was eradicated from the world

Polio has been eradicated in the Western Hemisphere- still see some wild cases particularly in Afghanistan, Pakistan (not eradicated), Syria (has had outbreaks in refugee camps)

Measles- in the US have had recent outbreaks

24
Q

Rabies

what does it affect

what is the infectious agent

where is it found

how is it transmitted

what is the port of entry

A

Fatal disease of the nervous system

Infectious agent: Rabies virus

Is found in wild and domestic animals such as
- Dogs
- Raccoons
- Bats

Transmitted by the saliva of an infected animal

Port of entry: broken skin from bite or scratch

25
Rabies How can we break the chain? what can we do to cats and dogs what campaigns can we have what can be administered to wildlife who should get pre-exposure immunization Why not vaccinate everyone??
Rabies immunization for all cats and dogs - link 4 susceptible host Educational campaigns Oral administration of vaccine to wildlife Pre-exposure immunization - veterinarians, park rangers Why not vaccinate everyone??
26
Smallpox when was it eradicated what was the mortality rate what was the reservoir how was it transmitted how was it eradicated
Declared eradicated in 1979. The last known case was in 1978. High mortality rate-30% NO animal or environmental reservoir. Found only in humans Transmitted by respiratory droplets or direct contact Eradicated by “Ring Immunization”
27
Measles what is it the leading cause of what is the R0 and what does that tell you about the infectious rate of the disease what is the pathogen how is it transmitted how can it be controlled
The leading cause of vaccine-preventable deaths in children worldwide Highly infectious communicable disease-R naught (R0) of 18 Pathogen: measles virus Transmitted to humans by respiratory droplets How can this be controlled? - Immunizations - Isolation of those infected
28
rank the diseases on which is least to most contagious mumps hepatitis c ebola HIV measles SARS
Hepatitis C ebola HIV SARS Mumps measles ranked from most to least contagious
29
Polio what is it the main symptom that is it Characterized by what pathogen is it caused by what was the goal for eradication what Countries have never interrupted the transmission of wild polio: what is the main method of control
Characterized by flaccid paralysis Pathogen: poliovirus World Health Organization set a goal for worldwide eradication for 2000 Countries that have never interrupted the transmission of wild polio: - Afghanistan - Pakistan Method of control: immunization in early childhood
30
Immunizations how does it effect diseases what are the risks of it
Immunizations are the most effective intervention for preventing disease and promoting health Immunizations do not come without risks - Allergy to eggs - Allergies to components of vaccine (neomycin, latex, thiomersal) - Seizures - Guillain-Barre syndrome
31
Fear of vaccines what are people scared that it might cause what do some vaccines come with and what do some parents refuse to accept what is lost if many people do not get vaccine, what is once example why are pharmaceutical companies reluctant to develop vaccines
Fear of autism (MMR) and SIDS (pertussis) from vaccines Side effects do exist for some vaccines, Some parents refuse to accept risks Herd immunity is lost if many people do not get vaccinated - Measles outbreak example of losing herd immunity Pharmaceutical companies are reluctant to develop vaccines - Low profits - Risk of law suits
32
Public health what have measures been successful to do
Many public health measures have been successful in controlling disease but requires constant diligence What do you think are some issues that may result due to budget cuts?
33
Dengue Fever what is it and what are the 2 forms what are the symptoms what are the viruses that cause it
Dengue is an acute infectious disease that comes in two forms: dengue and dengue hemorrhagic fever. The principal symptoms of dengue are high fever, severe headache, backache, joint pains, nausea and vomiting, eye pain, and rash. Generally, younger children have a milder illness than older children and adults. Dengue and dengue hemorrhagic fever are caused by any one of four closely related flaviviruses, designated DEN-1, DEN–2, DEN-3, or DEN-4.
34
Dengue Fever was it an endemic, pandemic, epidemic etc and where how is it transmitted what animals can serve as a reservoir what was approved for this disease
Dengue is endemic in many tropical countries in Asia and Latin America, most countries in Africa, and much of the Caribbean, including Puerto Rico. Dengue is transmitted to people by the bite of an Aedes mosquito that is infected with a dengue virus. Monkeys may serve as a reservoir in some parts of Asia and Africa. Dengue cannot be spread directly from person to person. Susceptibility to dengue is universal. Residents of or visitors to tropical urban areas and other areas where dengue is endemic are at highest risk of becoming infected A vaccine was recently approved in US, only for those with lab confirmed previous infection. The best preventive measure for residents living in areas infested with Aedes aegypti is to eliminate the places where the mosquito lays her eggs.
35
Dengue Fever Cain of Infection Reservoirs: Portals of exit: Modes of transmission: Portals of entry: Factors in host susceptibility:
Reservoirs: Portals of exit: Modes of transmission: Portals of entry: Factors in host susceptibility:
36
What is One Health? what is connected what happens as the pop. grows what makes people more vulnerable to disease
It means that animals, humans and environment health care connected As the population grows, we interact with animals and the environment in new ways that increase the risk of becoming infected with new diseases Poverty, war, limited access to healthcare make people vulnerable to disease
37
What are some ways that infectious diseases are spread? how can it be spread through the globe how can it be spread through food what environment can spread pathogens quickly where do these viruses persist
Global travel: - New pathogens can be introduced via global air travel - One example is the SARS outbreak of 2003 ----Jumped from animals at an urban market in China and spread widely via global air travel - COVID-19 had a similar means of transmission Industrial food production - Farms are much bigger and more disruptive to natural ecosystems causing pathogens to spread quickly between wildlife, domestic animals and people - Avian Influenza (H1N1 & H7N9)- These viruses persist in Asia and Africa as wild birds infect poultry and are in close contact with people
38
How can viruses spread to humans? how often to viruses evolve and adapt to which host who do humans have contact with the transmit diseases what inssects most often carry disease what makes people have high risk of infections
Viruses evolve much faster and adapt to humans quickly Disturbing wildlife habitats, humans have much greater contact with animals that transmit viruses Countries response to disease threats Mosquitoes and ticks carrying virus into new habitats as seasons and climates change Without clean water and food waste disposal and medical care people have higher risk of infections
39
Viral threat: HIV/AIDS when was it first recognized is there a cure what are 2 ways of transmission
First recognized in the USA in 1981 There is no cure to date but many treatments to manage it Transmission: Sexual contact: ---Homosexual transmission is the most common in the US ---Heterosexual transmission is the most common around the world Sharing of needles - IV drug abusers at high risk - Medical use of unsterile needles
40
Viral Threat: HIV/AIDS how can it transmitted to child what is screened and what is the result
Transmission - Mother to infant - Prenatal or during birth - Breastfeeding Blood transfusions - We screen blood products in the US so not typically seen in the US but can occur globally if they do not screen blood products
41
How can we control transmission?
Education Behavior modification Treatment of drug users Distribution of condoms Clean syringes Needle exchange programs Abstinence
42
Other emerging viruses what are the 5 viruses and where are the outbreaks
Measles- 1282 cases in US during 2019 (372 cases in all of 2018) Ebola- Have had several outbreaks in west African countries in 2014-2016. Current outbreak in Democratic Republic of Congo (DRC) Monkey pox- have had outbreaks in Nigeria Hantavirus- Have had outbreaks in 4 corners of the US West Nile Virus- reported in more than 40 states last year Eastern Equine Encephalitis-rare but can be deadly
43
Influenza what kind of virus is it how often does it mutate what is antigenic shift vs drift how many people did the spanish flu kill
Influenza is an RNA virus like HIV It is constantly mutating so the vaccine must be changed frequently Periodically will have an antigenic shift-the influenza strain is drastically different from anything the population has been exposed to. - Antigenic drift-slight mutation in the sequence of the prevalent strain Spanish flu of 1918-1919 killed 20-40 million people worldwide Avian influenza (H5N1) and H1N1 are concerning
44
Bacterial Threats
Legionnaire’s disease Lyme Disease Group A streptococci E. coli 0157:H7 in food Antibiotic resistance - Natural progression of bacteria - Improper medical use - Use in agriculture - MRSA
45
Tuberculosis (TB) how does it rank in infectious disease worldwide how many people are infected when was there a resurgence people with what disease are at a much higher risk how is it transmitted what is the fatility rate of those not treated
TB is the leading cause of infectious disease worldwide - One third of the world population is infected There was a resurgence in the US in the early 1990s People with HIV are at a much higher risk TB is transmitted by respiratory aerosol droplets Fatality rate for untreated TB is 50%
46
Tuberculosis what are effective but must be taken daily what can improper use of it lead to what is DOTS
Antibiotics are effective but must be taken daily for several months Improper use of antibiotics leads to resistance, including multi-drug resistance—this may increase fatality rate Directly Observed Therapy (DOTS) works! - Best approach for preventing antibiotic resistance In 2007, the CDC revised its requirements for overseas medical screening of applicants for immigration to the US
47
Tuberculosis what are the Prime transmission sites for TB
Prime transmission sites for TB - Homeless shelters - Prisons - Urban hospitals - Riskiest behavior is breathing!
48
Prions
Also called transmissible spongiform encephalopathies Rapidly progressive and total brain diseases Not considered a bacteria or a virus- it is an infectious protein
49
Prions what is another name for the disease what stage of life does it appear what country does it have a history and what are other names of the disease who does the new variant affect and how do they get it regulations have been tightened om what
Creutzfeldt-Jakob Disease (CJD) Sporadic CJD is the most common CJD usually appears later in life Bovine spongiform encephalopathy (BSE) or “mad cow disease” has a history in Britain New variant of CJD (vCJD) in the UK affects younger people- thought to be caused by eating infected beef Regulations have been tightened on animal feed
50
Prions what are the symptoms what is there a deficit in how long does it take to progress
Clinical presentation of CJD: Fatigue, sleep disturbances, weight loss, headaches, anxiety, vertigo, malaise, poorly defined pain Deficits in higher cortical function Progresses over weeks to months to profound dementia
51
Prions what is another name for it which people was it found and during what years what disease does it result and what are the physical effects what does it eventually lead to how did people get this disease and in what gender
Kuru Found in Fore people of Papua New Guinea in the 1950-60’s Neurological disease is characterized by progressive loss of coordination and control over muscle movements Eventually leading to death Resulted from funeral rituals of cannibalism mostly in women because they ate the brain
52
Public Health Response to Emerging Infections what is there a global surveillance for what is improved what is there a reduction in and what can be done as a response
Global surveillance of potential epidemics Veterinary surveillance Improved public health capacity Reduction of inappropriate use of antibiotics - Educate to not use antibiotics for viral infections