U.S healthcare exam 3 Flashcards

(226 cards)

1
Q

for Germany

  • what is mandatory
  • is the health insurance public or private
  • does the government mandate insurance, does employment provide it

how much does each employee get?

A

Mandatory sickness funds

Predominantly private

Government-mandated, employment-based private insurance
7.3% is employer responsibility; 7.3% withheld from pay; equals 14.6% for each employee

2009-government run health fund distributes health funds based on risk adjustment

Not allowed to exclude, or raise rates according to age or medical condition- which would be experiential rating

Remain in fund if ill, retired, lose job
Higher income can select private insurance

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2
Q

Germany
what kinds of appointments are common

how can you see a specialist?

how many generalists are there

what is there little coordination between

the patient receives no bill for what

A

Appointments with Primary Care is common

Allowed to make appointments with specialists without a referral

Over 40% of physicians are generalists

Little coordination between hospitalists and generalists

Appointments, labs, prescriptions, hospitalization=No bill to the patient

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3
Q

Germany

who. does a primary physician bill

how often are physicians reviewed?

how often are hospitalists billed

A

Primary physician  Bills regional Association of Physicians

1986- began to cap spending- Rationing

Physicians are reviewed quarterly, with each quarter affecting the following quarter

Hospitalists are billed upon Episode- Based funding or Bundle payment

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4
Q

Germany cost control
what are the parts of concerted action?

what does it control

despite the best healthcare effort, what still continues to rise

A

Concerted Action
- Guideline Fees
- Hospital Rates
- Pharmaceuticals

Controls physician fees, capping physician fees

Throughout time still Germany has Gross Domestic Product (GDP) that has been rising since 1990

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5
Q

Canada
to get health insurance what must you show

for the Hospital Insurance Act who is and who is not covered

when was universal medical insurance made available

how is health care system financed

is it attached to employment

how does everyone contribute to health care

who gets no bill

what does private insurance allow for

A

Health insurance: show provincial government card

Hospital Insurance Act: Hospital coverage but no MD coverage

Universal medical insurance 1966

Tax financed, public, single-payer health care system

Funded with provincial and federal tax revenues

Not attached to employment at all

Everyone contributes through taxes-everyone benefits

No bill if part of provincial health service

Private insurance allowed for gaps: some pharmaceutical coverage or private hospital rooms

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6
Q

Canada

who refers to a specialist?

what happens to specialists who receive a referral

what is waiting like for elective procedures

what happens per capita

what still remains despite everyone being covered

A

Family physician  referral to specialist

Specialists get paid best if referred

Longer waiting for elective procedures

Less services per capita than US for example: MRIs and surgery

Despite everyone being covered, inequities still happen

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7
Q

Canada
who does physician bill

how are they paid in full

who can the physician not bill and what must they agree with

what kinds of methods are used

what is the rate of the hospital services and hwy

what di hospitals not need to do

A

Physician bills provincial government

Paid in full according to fee schedule

Physicians must agree with payment, cannot bill patient

methods:
- Blended models

  • Fee-for-service
  • Capitation

Hospital services slow - not enough money to pay extra

Hospitals do not need to prepare itemized bills

Approval process for capital projects of hospitals

Regulation of pharmaceutical prices

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8
Q

what is the difference between Canada vs. US

A

Canada vs. US
Less administrative costs
Less expensive high tech costs
Lower pharmaceutical prices

Caps on payment (Similar to Germany)

Changes in 2010 due to lack of confidence

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9
Q

UK
what entitles you to healthcare

what is the NHS

what can compete with NHS

how many buy health insurance

who can pay for private hospitals

A

Being on the “soil” entitled to receive tax supported medical care through NHS –National Health Service

Private health insurance can compete with NHS

11% buy private health insurance

Private insurance can pay for care of private hospitals not NHS facilities

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10
Q

Britain
what do you need to see a specialist

what must you have

what does your GP act as

where are the GPs

how is home health care

A

NHS – need referral to specialist

Must have general practitioner

GP is primary care, local hospital is secondary care, regional/national hospitals is tertiary care

GPs not in hospitals, but with social services

Home care is highly developed in UK, doctors home visits

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11
Q

UK

what does home health care warrant

how does a doctor see their patient

what do consultants equal

what is awarded

A

Capitation for MD & Preventive care fee for service

Home visits, nights and weekends, fee for service

Consultants = Specialists

Quality is awarded

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12
Q

UK
what is lengthened

what is limited

what are there fewer of

how do they view technology?

A

Queues lengthened

Capitation and salary for physicians

Limited consultant slots- controls supply of personnel and facilities

Fewer surgeons

Fewer meds

Fewer x-rays

More skeptical of new technology than US

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13
Q

Japan
what must large companies provide

what health insurance do smaller companies have

what health insurance do self employed and retirees have

what health insurance do government workers have

what do they all have

what is the insurance a mix of

A

Large companies- required to operate self-insured plan for employees and dependents

Smaller companies-single national health insurance plan

Self-employed workers and Retirees- National Health Insurance or Citizen’s Health Insurance

Government workers- society managed insurance

All have standard comprehensive coverage

Mix of employment-based insurance, social insurance, universal insurance

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14
Q

Japan
are there pre-authorizations

are there restrictions

are there more hospitalizations

is there more surgery

how long are their hospital stays

A

No pre-authorizations
No restrictions
Less hospitalizations
Less surgery
Longer hospital stays

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15
Q

Japan
what is the basis

how are hospitals paid in 2003

what does government strictly regulate

what volume do physicians see their patients

what is the average amount of physician visits

who many times have physicians see their patients

what can physicians do for meds

what do patients also see physicians for

A

Fee-for service was the basis

2003 hospitals paid per diagnosis, physicians still paid fee-for-service

Government strictly regulates physician fees, hospital payments, medication pricing, number of expensive services

Physicians have high volume of seeing patients

Average physician visits: 13 per capita in Japan versus 4 per capita in US

Physicians may see 60 patients in a day

Physicians can dispense medications and profit from medications dispensed

Some patients see physicians just for refills

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16
Q

Japan
how is the GDP looking

what does health care system rely on

what is problematic for this structure

are the elderly decreasing and at what rate

how about for the U.S how is the elderly pop. looking

how are costs contained

A

GDP increasing 7.7% in 2000 to 10.3% in 2012

Healthcare system relies greatly on employer taxes

Low birth rate and longer life expectancy is problematic for this structure

Japan estimated 65 and older population is projected to increase from 12% 1990 to 39% in 2050

US 65 and older population also growing but not as quickly from 13% in 1990 to 21% in 2050

Costs are contained with strict fee schedules but may not be able to sustain
with older facilities and potential underfunding of the healthcare system

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17
Q

Benefit Package:

A

the additional perks and benefits a company provides to its employees in addition to the employee’s base wage or salary

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18
Q

Patient Cost Sharing:

A

The share of costs covered by your insurance that you pay out of your own pocket.

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19
Q

Effects on existing health care coverage

A
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20
Q

Cost Containment:

A

a process of judiciously reducing costs in a business or limiting them to a constant level

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21
Q

Reform Health Care Delivery:

A

a process of change involving the what, who, and how of health sector action

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22
Q

which label is best for patients and why

A

second one is better for reading and understanding

Spacing, information being available, name is easily found, directions is higher up

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23
Q

what do patients like and don’t like

A

like:
color, bolding, large font
white space
what drug is for
The most important info on top
name of medicine
prescriber name

don’t like
info for pharmacists
confusing dates
addresses
clutter
unclear directions (twice daily)
all capital letters

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24
Q

Health Literacy

Word Choice

A

What info they can use to understand their own health

Things related to them to help them decide their health

Numeracy is saying, I’m going away and how much do I need, when is my next refill

Take medicine is different than. Give, give for giving to child so parent should not take It

Take once in morning and at night is different than Twice a day so that the first one is better

Can be very important

Can be difficult for people to understand

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25
Health Literacy and Numeracy
From 2013 Majority of people are below the proficient level of understanding their health and health brochures Try to get convo. To 5th grade level, fewer syllables is better Break things down for folks
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Patient Literacy Assessment Tools
Zone in one this Use to assess someone’s ability to understand material Look at these tests How many grams of total carbs are in ½ cups: 13g Have to teach people these things cause not everyone can do these word problems Things to know to counsel patient Health literacy tools make sure student can say these words and you will see how literate they are based on the words they say Is kidney more associated to urine or fever?
27
Health Literacy Readability Assessment Tools
SMOG (“Simple Measure of Gobbledygook”) Readability Test Fry Readability Test Flesch-Kincaid Grade Level Readability Formula SAM (Suitability Assessment of Materials)
28
SMOG Conversion Chart
For looking at a booklet Take 30 sentences and see how many words have 3 or syllables Put hand on chin, every time your jaw drops then it is a syllable
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Fry Graph what does it show you how does it do it what do you want on in a pamphlet more syllables equals what what do we want for sentences
Average # of sentences and average # of syllables per 100 words Section 100 words and how many sentences are made for 100 words Least amount of sentences More syllables = more difficult for person to read Want short sentences and fewer syllables
30
how to do Flesch-Kinaid assessment
word file options show readability stats
31
Making a Difference how can you fix the label where do we need to improve labeling
Label is not easy to see Patient centered labelling We need to improve labelling of OTC
32
Health Literacy and drug coverage what do people not tend to understand can a lot of people figure out cost of hospitalization what must we make sure a patient knows what can "take 1 tablet every day" mean when is the best time to take statin what must pharmacists be in order for there to be better outcomes Rx label instructions
Ppl did not understand their health insurance Only 11% of people could figure out the cost of hospitalization Make sure that we know if the patient understands the med Take 1 tablet every day- can take it anytime Best time to take statin - at night time because cholesterol is made at night so you take at night to reduce how much is made in the body Tell them when to take it Be more specific for better outcomes Based on Rx directions, effects health outcomes
33
Four Major Actors in Conflicts, Change, Tensions, and Challenges who are they how do they relate to each other
Purchasers supply the funds Insurers receive the funds, pay providers Providers provide the care, all health care providers Suppliers provide the treatments and supplies to providers
34
who makes up the healthcare industry what was this like in the past what is it like now and is there a discrepancy
Insurers, providers, and suppliers make up the healthcare industry. Previously: - Gain for health industry  Thought of as an investment in economics of the nation Now: - Too much to pay, purchasers want to reduce the amount spent while health care wants the number to increase
35
Provider-Insurance Pact 1945-1970 who formed the alliance of insurers and providers and was their competition who decided on payment provisions of medicare & medicare who had the upper hand in negotiating generous payments who paid without much question who paid for insurance and recieved tax benefits were there complaints what was growing and was profitable who is able to pay for benefits who was charged for new facilities and construction? who is benefitting
Alliance of insurers and providers Many independent hospitals Lack of competition Hospitals and insurers decided payment provisions of Medicare and Medicaid Providers had the “upper hand” in negotiating generous payments Insurers paid without much question Employers paying for insurance and receiving tax benefits; no real complaints of increased costs Businesses growing and profitable Able to pay for benefits *Hospitals even charged for facilities and new construction* who benefits: purchasers, insurers, providers, suppliers
36
Perception of 1970s what decreases what does this result in what becomes a rising concern in healthcare what is the result when does regulation begin what is the result who begins utilization reviews who benefits
US share of world industrial production decreasing from 60% in 1950 to 30% in 1980 - Lower profits - Purchase cash flow decreased - Inflation and unemployment on the rise New economic reality of less money for individuals and companies, becomes increased concern for the rising costs of health care - Hospitals being regulated for new construction - Government begins health planning agencies Regulation begins after Blue Cross increase of premiums 25% to 50% in a single year Utilization reviews begin by insurers - Provider-insurer tensions rise - Insurance-provider pact unravels-Blue Cross separates from the AHA insurers benefits purchasers and suppliers do not benefit providers benefit only half way
37
Coverage Landscape Changes-1990’s what does the plan become specific to what do employers shop around for what do providers lose and why what power do purchasers have and what was the result who benefts
Plan become very specific as to where and from whom care can be provided and covered Employers shop around more for insurers Providers would lose contracts due to poor rates and unwillingness of insurers to negotiate Purchasers had some negotiating power with HMOs and saw a drop in premium growth in the earlier 1990’s providers do not benefit purchasers benefit insurers benefit only 50% suppliers remain steady
38
1980’s Purchasers Pay Attention what result did the Costs increase for employer-sponsored health plans result in what did the Business more attentive to costs and health care issues result in what rose and who was droped from plans what did the Selective contracting of purchasers = In-network and Out-of-Network result in what is tighter controlled who benefits
Costs increase for employer-sponsored health plans By 1989 =20.4% of business expenses (it was a fraction of the cost from1945-1970) Almost a double increase (from 5% to 9%) of payroll spent on health care benefits Business more attentive to costs and health care issues Large companies start self-insurance More companies use managed care options such as HMOs as cost-control Individuals and labor unions see shift of costs to them; complain of health care costs Rising premiums and policy cancellations for those with chronic illnesses become media headlines Selective contracting of purchasers = In-network and Out-of-Network Insurers choose providers to contract with (those that provide cost containment) Shift from fee for service to capitated reimbursement-causes providers to cost-control as well Medicare payments are tighter controlled and Medicaid is scaled back insurers, purchasers and suppliers dod not benefit at all but suppliers remain steady
39
what did the Counter-revolution by providers/Consolidation in health care market result in what did the Growing power of specialists and specialty services result in who benefits
Counter-revolution by providers/Consolidation in health care market Provider and insurance negotiations are intense Costs accelerate especially for the individual employee-Premiums and deductibles rise 34% Large HMOs emerge due to buy-outs and consolidation Growing power of specialists and specialty services For-profit services, physician owned imaging facilities Specialist physician groups grow and negotiate for higher payment rates from insurers Ambulatory centers for day surgery and clinics grew and are physician owned Hospitalists are a growing specialty purchasers and insurers benefit providers and suppliers do not benefit
40
Pharmaceutical industry criticisms in 1988, how much of the national health expenses was Rx vs how much in 2009 what happens after that and what did the insurances challenge the pharmaceutical companies to begin how much did Most profitable companies earn were there regulations to regulate prices what tactics were used to continue market share and what act was this what were the generic manufacturers doing what was evergreened what is Pharmacy Benefit Managers (PBM) part of and responsible for what who benefits
Pharmaceutical industry criticisms - 1988 Rx was 5.5% of national health expenses versus in 2009 10.1 - Shift of insurance coverage of Rxs occur; Insurances take notice and begin to challenge pharmaceutical costs; Tiers begin - Most profitable companies: earning 20% of revenues compared to other Fortune 500 companies that earn 5% of revenues - No regulations by the government to regulate prices - Brand to generic tactics to continue market share-Hatch-Waxman Act - Generic manufacturers are consolidating driving up generic costs - “Evergreening”- Immediate release vs extended release – Rx to OTC Pharmacy Benefit Managers (PBM) --Part of the supply chain and responsible for formularies suppliers benefit
41
Primary Care Shifts what method of payment do primary care practices look for what is payment for patient-oriented care, is it rising or declining what is forming
Primary care practices looking at capitation versus fee-for-service Choosing Wisely campaign spotlights overuse of health care http://www.choosingwisely.org/patient-resources/ Payment for value versus volume Patient-Oriented care on the rise Primary care teams are forming
42
Suppliers The Perfect Health Care System is it realistic what are the important factors of health care systems
Noble aspirations but most likely impossible to attain 100% Important factors of health care system: Improve health Control costs Prioritize allocation of resources Enhance quality of care Distribute services fairly
43
Blurring of the Actors
Insurers acquiring Providers: UnitedHealthcare acquired DaVita Medical Group Providers acquiring Insurers: CVS merging with Aetna Providers acquiring Suppliers: CVS merging with Caremark Insurers acquiring Suppliers: Cigna merging with ExpressScripts Companies moving into health care: Amazon
44
Many conditions have increased during the pandemic. what are Additional Barriers to Care
Travel costs and arrangements Childcare Time off work Therapy costs and insurance coverage
45
HEALTHCARE IS CHANGING what have patients adopted where is the center of health do providers meet patients now
Patients have adopted a consumer mentality towards engaging in their health seeking to meet their needs on demand. Home as the center of health is a quickly growing area of focus in medicine including the 'Hospital at Home' model Meeting patients where they are at is a growing healthcare business structure across multiple care modalities.
46
Why Digitalize Healthcare? what issues can they help address the following issues:
Digital tools are giving providers a more holistic view of patient health through access to data and giving patients more control over their health. Digital health offers real opportunities to improve medical outcomes and enhance efficiency. Reduce inefficiencies Improve access Reduce costs Increase quality Make medicine more personalized for patients.
47
how many physicians and federal acute care hospitals (96%) adopted a certfied EHR
As of 2021, nearly 4 in 5 office-based physicians (78%) and nearly all non-federal acute care hospitals (96%) adopted a certified EHR. This marks substantial 10-year progress since 2011 when 28% of hospitals and 34% of physicians had adopted an EHR.
48
what can you do during. TELEHEALTH talk to who message who
Telehealth — sometimes called telemedicine — lets your health care provider care for you without an in-person office visit. Telehealth is done primarily online with internet access on your computer, tablet, or smartphone. Talk to your health care provider live over the phone or video chat. Send and receive messages from your health care provider using secure messaging, email, and secure file exchange. Majority of payers cover telehealth services for members Expansion of services available pre-pandemic Mental and psychological health over state lines
49
Remote Patient Monitoring (RPM) what do devices monitor what does CPT do what can RPM be used for what do some patients need what are some disease states that it monitors
Devices monitor physiological data from patients CPT codes for setting up and monitoring data available from CMS RPM can be used for many conditions that require physiological data indicative of disease management Some patients will need in-person testing, diagnostics, or monitoring. This depends on their condition, Internet capabilities, or personal preferences and abilities. But there are many ways that remote patient monitoring can help with chronic conditions, pregnancy complications, and short-term illness. High blood pressure Diabetes Weight loss or gain Heart conditions Chronic obstructive pulmonary disease Sleep apnea Asthma
50
what is Remote Therapeutic Monitoring (RTM) what does it cover
Combination of technology like RPM devices and disease management for therapeutic outcomes This can include medication adherence and physiological data Interventions can include education and coaching Currently, CMS covers pulmonary and musculoskeletal conditions CPT code 98976 - RTM (e.g., respiratory system status, musculoskeletal system status, therapy adherence, therapy response); device(s) supply with scheduled (e.g., daily) recording(s) and/or programmed alert(s) transmission to monitor respiratory system, each 30 days.
51
DIGITALIZATION OF DEVICES what does the Integration of health devices do what is also integrated what are the ongoing issues
Integration of health devices into the ‘Internet of Things (IoT) landscape approaches include: Integration of Bluetooth to tether to an external device (e.g., smartphone or peripheral) Mobile app integration for data collection and user engagement Enabled the movement towards: Remote Patient Monitoring (RPM) Remote Therapeutic Monitoring (RTM) Ongoing Issues: Accuracy, data interoperability, coverage, patient education, user adherence
52
RISE OF CGM what does it result in fewer of what is the accepted use for what are the limitations
Increased desire amongst PwD to utilize CGM over other BGM interventions due to fewer finger pricks and convenience Visually impaired patients have benefited from easier BGM Digital affinity closely related towards acceptance of the use of CGM technologies - This is likely to increase over time with digital natives Increased recommendation of CGM use in clinical practice guidelines influencing clinician behavior Limitations still present: Cost barriers Clinician and patient buy-in Technology barriers
53
what is the center of healthcare or the ____ at ____ model
hospital at-home model home is the center of care ER/provoder identificaton of patient identification of valid patient conditions of defined treatment protocols - HF, COPD, CAP, cellulitis patient home is within hospital range to provide emergent care home must have space and fit patient needs - food, heat/cooling, water health staff visit patients in the home (ex. respiratory therapist, nursing)- kinda like UK! tests conducted in the patient home and therapy (ex. medications) given as well RPM will play a significant role
54
Why is PH Controversial?
19th century public health closely tied to social reform movements: campaigns for improved housing, trade unions, abolition of child labor, child and maternal health Public Health viewed as a broad social movement Winslow’s 80 yr old definition: the role of PH is the development of the social machinery to ensure every individual in the community a standard of living adequate for maintenance of health.
55
Why is PH Controversial? Contrasting views that direct the production and equitable distribution of scarce health care resources
Distribution of benefits/burdens and responsibilities within a society Free market vs government responsible for allocation and delivery of resources Health care access a right vs ability to pay Health care an individual vs collective responsibility Role of PH in society, broad and expansive vs restrictive
56
Social Justice in PH
Health is a collective responsibility Emphasizes community well-being Views health care as a social resource Allocation and delivery of health care resources governed by need Minimum levels of income, housing, employment, education and health care are fundamental rights PH closely tied to social reform movements (public hygiene, improved housing, abolition of child labor, maternal and child health, trade unions
57
Social Justice in PH what two things does it emphasize what is it a strong obligation to is access to healthcare universal or limited what does it propose
Emphasizes collective responsibility for health Emphasized community well-being Strong obligation to the collective good Access to health care universal Proposes public solutions to social problems (drug abuse, homelessness, violence)
58
Market Justice. in PH
Health is an individual responsibility Emphasis on individual well-being Views health care as an economic good Allocation and delivery of health care resources governed by demand Powerful forces of environment, heredity, social structure prevent equitable distribution of the burdens and benefits of PH
59
Market Justice in PH what does PH aim to control who encourages it what does it limit how is medical care distributed
PH is an enterprise focused on controlling communicable disease or as a safety net that provides medical care to the indigent Encouraged by MD’s Limits federal health funding to programs run by local health departments Medical care distribution based on the ability to pay
60
Market Justice access to medical care how is access to medical care viewed what is the role of the government and public health
Access to medical care is viewed as an economic reward for personal effort and achievement Role of government and public health - Restricted, narrow - Limited to a technical enterprise
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Sources of Controversy
Economic impact Individual liberty Moral and religious concerns/values Political interference with science
62
Economic Impact in PH
PH measures may have negative impact on segment of population or industry Those paying for PH measures may not benefit from those measures Costs are measurable/benefits are often not Costs may be short-term while benefits may not be immediately seen Example of a PH initiative with significant economic impact? Discuss in groups of 3 to 4.
63
Economic Impact industries
Tobacco industry: product labeling, bans on smoking in public places, restaurants Lumber industry: regulations cost jobs to preserve a long term stable climate Standing orders for Narcan in community pharmacies: high cost to insurance companies Mandatory immunizations
64
Individual Liberty in PH what is the role of the gov't in this what are restrictions on what may the restrictions benefit
To what extent can and should the government restrict individual freedom for the purpose of improving the community’s health Restrictions on behaviors that may cause direct or indirect harm to others Restrictions may benefit the individual or the community Example of PH initiative affecting individual liberty?
65
Individual Liberty what do people have a say in
Seat belts Bike helmets Extra large soft drinks Removal of vending machines in public areas Additional driving tests for elderly Mandatory health screenings Mandatory immunizations
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Moral and Religious Concerns in PH what do some PH initiatives do are discussion of PH issues always comfortable to have how may some religions react to PH initiatives
Some PH initiatives provoke moral or religious objection Discussion of some PH issues are offensive or embarrassing to discuss (sex and reproduction, alcohol and drug addiction, suicide and end of life decisions) Can the government determine and enforce moral behavior? Some religions may prohibit some common PH initiatives (birth control, immunizations)
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Politics vs. Science
Presidential administrations criticized for misrepresenting and/or distorting scientific information and evidence to support its policies and political agenda Examples: Bush admin pressured CDC to promote abstinence only programs for preventing teen pregnancy Promoted condom failure rates rather than place in prevention of spread of AIDS and other STD’s Prevented publication of research on agriculture affect on antibiotic drug resistance Handling of the AIDS crisis Handling of drug/alcohol addiction crisis
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Health Statistics in PH how do PH workers monitor health of a community what does health statistics deal with
Public health workers monitor the health of a community by collecting and analyzing health data Health statistics - Identify special risk groups - Detect new health threats - Determine success of disease state management - Help plan and evaluate success of public health programs - Are considered when preparing government budgets
69
Health Statistics for research
Provide raw data for research on Epidemiology Environmental health Social and behavioral factors in health The health care system Essential for the Assessment Function in public health
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NCHS what does it stand for what does it do what is it a part of how many ways does it collect data and what does it do
National Center for Health Statistics Primary agency that collects, analyzes and reports data on the health of Americans Part of the CDC Collects data in two ways - States and local agencies periodically transmit data they have compiled from local records: vital stats, births and deaths - Conducts periodic surveys of representative samples of the population on health status, lifestyle, health-related behaviors, onset and diagnosis of illness and disability, use of health care resources
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Vital Statistics
Births and deaths are the most basic and reliable and complete data set Causes of death subject to uncertainties Utilize birth and death certificates Vital Statistics also include information on marriage, divorce, spontaneous fetal deaths and abortions The state health department is generally responsible for collecting these reports and transmitting them periodically to the NCHS
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Birth Certificates who supplies info about baby who supplies medical and health info
Mother supplies information about the baby’s family (names, address, ages, race, ethnicity, education level) Medical and health information supplied by hospital, doctor, birth attendant (prenatal care, birth weight, medical risk factors, complications during delivery, OB procedures, abnormalities in the newborn)
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The Census what is the # of people in society important what is used as a numerator and what is used as a denominator how do you calculate age adjusted or age specific rates
The number of people in the population is necessary in order to convert the data collected through vital statistic systems into rates per number of people The number of people in the population serves as the denominator when a vital statistic is used as the numerator. To calculate age-adjusted or age-specific rates it is necessary to know how many people are in each age group
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The Census what does it determine how often does the constitution require that the population of the U.S be counted to determine the state representatives what are the two controversial issues presented
To determine sex-specific or race-specific rates, we need to know how many males and females there are in a population as well as the breakdown of races within the population The Constitution requires that the population of the United States be counted every 10 years to determine each state’s representation in the House of Representatives 2 controversial issues - How race is determined - Ability to accurately count every individual household
75
The Census. what is the major change what is the American Community Survey (ACS) was it different than the long form who was it sent to what was it designed for
A major change in the way the 2010 census was conducted was that only - the most basic data was collected using a short form (included name, sex, race and ethnicity, and relationship of everyone living in the household) American Community Survey (ACS) launched in 2005 by the Census Bureau - Same information as long form - Sent to 3 million households selected to be representative of the populations of local jurisdictions - designed to help communities plan for transportation systems, zoning, schools, healthcare facilities, housing and social services
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National Center for Health Statistics Surveys
In addition to collecting data from the states, NCHS actively conducts a number of surveys to gather additional information on the health of the American public Two ongoing NCHS surveys The National Heath and Nutrition Examination Survey (NHANES) Designed to obtain detailed and accurate information Doctors and nurses conduct physical and dental exams and lab tests on a carefully selected sample of the population Data collected determines prevalence of chronic conditions and risk factors as well as nutritional status and its association with chronic disease
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NCHS Surveys what does the BRFCC do
Two ongoing NCHS surveys The Behavioral Risk Factor Surveillance Survey (BRFSS) - Largest telephone survey in the world - Self reported data (may be less reliable) - The only available source of timely, accurate data on health-related behaviors - Conducted by the states which report their findings to the CDC - Asks questions about health status, high risk behaviors, physical activity, preventive medical care
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NCHS Surveys examples
National Youth Fitness Survey National Survey on Family Growth National Immunization Survey National Asthma Survey in collaboration with the CDC National Center for Environmental Health National Infant Feeding Practices Study
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Other Governmental Surveys
EPA surveillance for health hazards in the environment National Cancer Institute monitors long-term trends of cancer incidence and mortality through a program called Surveillance, Epidemiology, and End-Results (SEER) The Centers for Medicare and Medicaid Services utilize billing records for research on utilization and outcomes of medical care
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Is so much data necessary?
Data is critically important in making up the surveillance systems that form the basis of effective public health practice as well as the planning and evaluation efforts that are increasingly being used in public health programming The success of intervention programs to confront a problem is evaluated based on whether they improve the statistics
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Accuracy and Availability of Data what is the process of data collection health info. always relying on survery or voluntary reports are always what is the census info. always reliable
The process of data collection is always imperfect Health information relying on surveys or voluntary reports are often incomplete or subject to bias Census information contains errors and there are political difficulties in attempting to correct these errors
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Accuracy and Availability of Data errors
Errors exist in reporting cause of death on death certificates Maternal deaths are suspected of being underreported because doctors fail to indicate the woman was pregnant on the death certificate The data collection and reporting processes contain sources of inaccuracy and bias
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Accuracy and Availability of Data
New information technology (public health informatics) has vastly improved accessibility of information to public health workers and the general public
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Confidentiality of Data
All information collected from individuals by governments for whatever purpose is considered confidential and cannot be divulged without the consent of the individual Information is generally entered into a database without any names, addresses or personal identifiers Exception: when someone has been exposed to a communicable disease they must be notified
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Data and PH Interventions
PH problems are identified in terms of statistics Data is the basis of the statistics utilized in PH initiatives Success of PH initiatives is evaluated based on improvement in statistics
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Pharmacist Patient Care Process C A P I F
collection of the necessary subjective and objective info. about the patient to understand the relevant medical/medication history and clinical status of the patient the pharmacist assesses the clinical effects of the patient's therapy in the context of the patient's overall health goals to identify and prioritize problems and achieve optimal care develop a plan to combat the issue that is evidence-based and cost-effective put a plan into place with other health care professionals and patient or caregivers evaluate the effectiveness of the plan
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Policy Development what does it help to develop what does it determine what does it inform what does it develop what does it used to devise strategies
Development of the treatment plan Determines what will be done Informs, educates and empowers people about health issues Mobilizes community partnerships to identify and solve health problems through DPH Develops policies and plans that support individual and community health efforts Uses scientific knowledge to devise strategic approaches to improve community health
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Public Health WHAT WE FOCUS ON
The role of the pharmacist
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Public Health what is it a measure of what else does it measure in regards to bringing and maintaining
Measure of the general, overall state of health of a population or society Measures that people take to bring about and maintain the health of a population or society
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What is Public Health 1920 definition, Charles Edward A. Winslow
The science and the art of preventing disease, prolonging life, and promoting physical health and efficiency through organized community efforts for the: Sanitation of the environment Control of community infections Education of individuals in principles of personal hygiene Organization of medical and nursing services for early diagnosis and prevention of disease Development of social machinery which will ensure to every individual a standard of living adequate for the maintenance of health
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PH From the CDC Foundation what is PH what does it improve
Public health is the science of protecting and improving the health of families and communities through promotion of healthy lifestyles, research for disease and injury prevention and detection and control of infectious diseases.
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CDC works with its partners around the world to do what
monitor health through epidemiology detect and investigate health problems conduct research to enhance prevention develop and advocate sound public health policies implement prevention strategies like with covid: masks, 6 feet away promote healthy behaviors foster safe and healthful environments provide leadership and training
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What is Public Health what is the mission what does substance mean
1988 definition, The Future of Public Health by the Institute of Medicine (4 part definition) Mission: The fulfillment of society’s interest in assuring the conditions in which people (population not individuals) can be healthy Substance: Organized community efforts aimed at the prevention of disease and the promotion of health
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What is Public Health
Organizational framework: encompasses both activities undertaken within the formal structure of government and the associated efforts of private and voluntary organizations of individuals 3 Core functions of public health (Table 1-1) *on exam* Assessment Policy Development Assurance that policies are working
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Assessment – identify what needs to be done what does it determine what does it examine what does it require
The diagnostic function- what do we need to do Determines what should be done Examines the current health status and threats to health that exist in a community Requires surveillance of disease, identifies needs, monitors trends and analyzes causes Diagnoses and investigates health problems and health hazards in the community
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Assurance what is it equivalent to what does it determine what does it enforce what does it link. what does it ensure what does it evaluate
Equivalent to the actual treatment plan Determines what is being done Enforcement of laws and regulations that protect health and ensure safety (interventions) Link the public to health services and ensure the provision of health care Assure a competent public health and personal healthcare workforce Evaluate effectiveness, accessibility, and quality of personal and population-based health services
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3 Core Functions
assessment policy development assurance
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Public Health
Prevents epidemics and the spread of disease Protects against environmental hazards like hurricanes and such Prevents injuries Promotes and encourages healthy behaviors Responds to disasters and assists communities in recovery Assures the quality and accessibility of health services
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Public Health vs Medical Care what is the focus of PH what is the goal how much does PH account for in health spending who are the PH decision makers
Public Health: - The “Patient is the Community” - The goal or focus is on prevention (abstract, difficult to quantify and recognize) - Accounts for approximately 3% of health spending - Decision makers are public health experts, involve scientific recommendation/evidence-based medicine, government intervention
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Public Health vs Medical Care
Medical Care -The Patient is an individual - The goal or focus is to treat and cure those who are ill (benefits are easier to quantify and recognize) - Accounts for approximately 97% of health spending - Decision makers are physicians, mid-level providers, and the individual patient
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Public Health vs Medical Care what are the core functions for each
Public Health core functions: Assessment, Policy Development, Assurance Medical Care core functions: Diagnosis, Providing Treatment Options, Actual Treatment, easier-to-quantify implementation
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PH: Science plus politics what is science what is politics
Science: the understanding of threats to health, determining necessary interventions, evaluating efficacy of interventions Politics: determine policies for development, implementation, and assurance
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Six sciences/disciplines of Public Health
Epidemiology Statistics Biomedical Sciences Environmental Health Sciences Social and Behavioral Sciences Health policy, management, and administration - need to be thoughtful
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Epidemiology what is it what is it the study of what does it seek what does it aim to control
The basic science of public health - need to know what's going on in pop. before developing interventions The study of epidemics (or common exposures, shared characteristics) Seeks causative factors of acute and chronic diseases and strategies to limit exposure Aims to control the spread of disease
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Statistics what does it provide and what does it help with what does the government collect what does it also assess
Data/numbers are diagnostic tools that aid in the determination of risk The government collects data on populations Statistics also assess the benefits of interventions
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Biomedical Sciences how much of disease is caused by microorganisms what does prevention and control require what does it lead to what studies does it include
A major proportion of disease is caused by microorganisms Prevention and control of diseases requires understanding of infectious agents Lead to understanding of risk factors for non-infectious chronic diseases Includes study of genetic predisposition and effects on disease risk, prevention and treatment
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Environmental Health Science what is it concerned with what does it share concern with what does it depend on what can we see in different communties
A component of public health Concerned with preventing the spread of disease through water, air, and food Shares concerned about the spread of infectious organisms Depends on epidemiology to track environmental causes of disease within certain communities, there might be environmental contributors that can affect life span ex: 84 life expectancy in 1 region and 72 life expectancy in another region
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Social and Behavioral Sciences
People are negatively impacted by diseases caused by their behavior and their social environment There are many disparities in health between subgroups of the population, the causes of the disparities are often unknown Some subgroups of the population have poorer health overall than others related to social and behavioral sciences disparities between white and black health outcome
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Health policy, management and administration what does it attempt to address
Attempts to address: Rising cost of healthcare Access to healthcare Quality of healthcare Role of public health in medical care
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3 Core Functions and 6 Disciplines what are the 3 core functions
How are the 6 disciplines used to accomplish the 3 core functions? -Assessment -Policy Development -Assurance
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Prevention and Intervention what is the 5 step process
5-step process: 1. Define the health problem 2. Identify the risk factors associated with the problem 3. Develop and test community-level interventions to control or prevent the cause of the problem 4. Implement interventions to improve the health of the population 5. Monitor those interventions to assess their effectiveness plan do study act this is a continuous cycle
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Prevention and Intervention what two things does PH address what does it require What are some interventions we see every day?
PH = prevention of disease PH = keeping a population healthy Prevention --Requires development of interventions aimed at specific health problems or behaviors What are some interventions we see every day? - billboards
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2 Approaches to designing interventions what are they? :)
Prevention at 3 levels/stages Chain of causation
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Prevention at 3 levels/stages
Primary prevention: aims to prevent an illness or injury from happening at all by preventing exposure to the risk (true prevention) - COVID: having people stay home, could not be exposed to COVID if they did not go anywhere, also masks Secondary prevention: aims to minimize the severity of the illness or injury when it occurs (early detection and treatment) Tertiary prevention: aims to minimize disability by providing medical care and rehabilitation. Happened in hospitals, aiming to minimize the severity and disability vaccinations are secondary preventions: were not designed to prevent COVID-19 but to prevent the severity of the disease if you got covid
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Examples of Prevention at 3 levels/stages did it prevent exposure?
Primary: discouraging teenagers from smoking and efforts to encourage smokers to quit (preventing lung cancer and COPD). Have laws in place to prevent ppl under 18 from getting cigarettes. Stop exposure Secondary: screening programs for early cancer detection Tertiary: medical treatment and rehabilitation for cancer patients
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Chain of Causation what are the 4 parts what does each involve
Involves Agent: could be a disease-causing bacteria or virus. The goal is to eliminate or minimize. For lung cancer: smoke or cigarettes. Anyhting that causes the disease Host: a human being. The goal is to make less susceptible/strengthen resistance to the agent like with a vaccine Environment: the means of transmission by which the agent reaches the host. The goal is to make the host less likely to encounter the environment and decrease or eliminate the means of transmission. For COVID: school, grocery stores, public transportation goal: make the host less likely to be in an environment
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Example of chain of causation example is suicide what is the host what is the agent what is the environment what is the PH prevention what do we need to reduce access to
PH goal: prevent suicides in the age group 15 to 24 Host: susceptible young people Agent: guns, overdose Environment: the young person’s social environment (family, school, social media) PH intervention: change messages in the media, reduce access to guns and drugs for overdose reduce access to guns, interrupt the chain of causation something needs to change
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Chain of Causation what is the goal what must to first think of identify what what must you describe how can you change the host
The goal is to interrupt the chain: Think of an illness or injury Identify the agent, host, and environment Describe how you would interrupt the chain of causation related to the agent, host, and environment can change host by vaccinating them, educating them
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Public Health and Terrorism Public health response to disasters and terrorism helps control damage and prevent further harm to survivors and rescuers. What level of prevention is this?-is it primary, secondary or tertiary
Public health response to disasters and terrorism helps control damage and prevent further harm to survivors and rescuers. What level of prevention is this? Primary?- prevent exposure to agent Secondary?- help to reduce the severity of agents like a vaccine Tertiary?- how we take care of people who have exposure evacuate from hazard: primary prevention terrorist attack: no primary prevention *I think* this is secondary because the disaster has ALREADY happened (so it cannot be primary because if it was then we would be preventing it from happening at all) and we are trying to prevent FURTHER harm from continuing. If tertiary then we would be providing something for the survivors to RECOVER from the disaster
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Why is PH controversial?
do not make a lot of money costs money
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Pharmacist Patient Care Process
also in PH by collecting assessing plan implement follow-up do this for pop. and not just individual
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Government’s role in public health who determines their role is the body of PH law small
Determined by law Government’s public health activities must be authorized by legislation at the federal, state, or local levels' The body of public health law is huge, consisting of all written statements relating to health by any of the three branches of government
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The U. S. Constitution what does it mention about health what does th 10th amendment state what does the preamble include what authority does it give to federal goverment
Does not mention health Tenth Amendment states that “the powers not delegated to the United States by the Constitution…are reserved to the States respectively. Preamble includes “to promote the general welfare” Gives federal government authority to regulate interstate commerce and “to collect taxes…to pay the debts and provide for the common defense and the general welfare:
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Federal influence over public health
Interstate commerce provision: justifies the activities of the Food and Drug Administration (FDA) Power to tax and spend: (1967) lead to federally mandated motorcycle helmet laws as a condition of federal funding for highways Federal government provides 50 to 80% of Medicaid funding though states and counties administer the programs
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Federal influence over public health
From WW II to the 1980s the federal government used its powers to widen its role in public health Trend reversed in 1980 due to politically hostile climate in government Movement in Congress and the Supreme Court to cut government regulations and return power to the individual states
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New federalism in the 1990s what did it do to congress what did the supreme court do what happened to new federalism after 9/11 what happened in 2003
Limited Congress’s powers and returned authority to the states Supreme Court struck down a law making gun possession within a school zone a federal offence, rejecting that gun possession was a matter of interstate commerce New federalism lost much of its momentum after 9/11 when the role of the federal government in public health looked useful and necessary In 2003 this movement seemed to reverse, giving federal law more power over state law
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How the law works what do the governments have power to do what are the 3 reasons why police power is invoked
Governments have police power (broad power) to act in ways that curtail the rights of individuals. Police powers are invoked for 3 reasons --To prevent a person from harming others (direct or indirect) --To defend the interests of incompetent persons such as children or the mentally handicapped --To protect a person from harming him or herself
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Examples of police powers what does it say about vaccines what about work training what did some people argue
Mandatory vaccinations Occupational Safety and Health Act (OSHA) Some may argue that prior to government implementing PH initiatives a cost benefit and feasibility analysis should be considered.
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How public health is organized and paid for
Local Agencies Have day to day responsibility for public health activities and provide the bulk of services (include collecting statistics, conducting communicable disease control programs, health screenings, immunization clinics, provision of medical care to the indigent) Organization varies from state to state (most common is county health departments, large cities have municipal health departments, towns have boards of health, rural areas have multicounty health departments ) Funding varies from state to state, including state, federal and local taxes, fees for services
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How public health is organized and paid for what are state agencies primarily responsible for what do most states have what does funding depend on what is it defned to what is it charged with
State Agencies - Has primary responsibility and authority for the protection of health, safety and general welfare of the population Most states have a state health department (Mass Dept of Public Health) Funding depends heavily on federal money Define to varying degrees the activities of local health departments Charged with licensing and certification of medical personnel, facilities and services Administer Medicaid programs
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How public health is organized and paid for who is the nation’s leading spokesperson on matters of public health what agencies are included
Federal Agencies Fall under jurisdiction of the Department of Health and Human Services (HHS) The Surgeon General is the nation’s leading spokesperson on matters of public health Agencies include CDC – the main assessment and epidemiologic agency (figure 3-4) NIH – the greatest biomedical research complex in the world (Box 3-1) FDA
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The CDC what is the mission what does it traditionally focus on what has the focus changed
Mission is to control and prevent human diseases Traditionally focus has been on infectious diseases (crisis oriented) Change in focus and expanded mission includes chronic diseases, genetics, injury, violence and environmental health
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NIH what is it in the world what does it support what does it include
The greatest biomedical research complex in the world Supports research ranging from basic cellular processes to physiological errors that underlie human diseases Includes the National Library of Medicine, the largest reference library for medical centers around the world
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Other federal agencies with public health responsibilities
Environmental Protection Agency (EPA) Department of Agriculture Department of Education Department of Transportation Department of Labor Department of Veterans Affairs Department of Homeland Security
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Worcester Department of Public Health (DPH) what does it work on what is it comprised of
Your Public Health Division works to protect and improve community well-being by preventing disease and injury while promoting social, economic and environmental factors fundamental to health. This Division is the foundation of the local public health system that comprises public- and private-sector health care providers, academia, community based organizations, business, the media and other local and state governmental entities.
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Worcester DPH what does it track and investigate what does it prepare and respon what does it develop, apply and enforce what does it lead
Track and investigate health problems and hazards in the community Prepare for and respond to public health emergencies Develop, apply and enforce policies, laws and regulations that improve health and ensure safety Lead efforts to mobilize communities around important health issues
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Nongovernmental role in public health what non-governmental organizations play a role in public health
Many nongovernmental organizations play important roles in public health, especially in education, lobbying and research American Cancer Society American Heart Association Alzheimer’s Disease and Related Disorders Association American Diabetes Association
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Non-governmental role in public health what do they conduct what do they sponsor what do they include
Conduct campaigns to educate the public Sponsor research on a particular disease Include professional membership organizations Include several major philanthropic foundations providing funding for supporting research or special projects, health care to certain populations and support for health and public policy development
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what are the Public Health Cores Sciences?
prevention effectiveness epidemiology laboratory informatics surveillance
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what is epidemiology what is Descriptive Epidemiology what is Analytic Epidemiology what is epidemiology concerned with
the study of - the patterns of disease occurrence in human populations, - the factors that influence these patterns - the application of this study to the prevention and control of health problems Descriptive Epidemiology: It looks to find the answers of person (who), place (where) and time (when) of a disease or other health-related event Analytic Epidemiology Why and how questions are answered by Epidemiology is not only concerned with only death, illness and disability; but also positive health states and the means to improve health
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what are the 3 Elements of Descriptive Epidemiology
Time: - Do disease patterns differ by time of year? Are they seasonal? Person: - Do disease patterns differ by age or gender? - Are certain groups of people at a higher risk of developing a disease or complications from an illness? Place: - Do disease patterns differ on geographical areas? Combination of time, person, & place Age groups stratified by location
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what is the Purpose of Epidemiology in Public Health Practice
Discover the agent, host, and environmental factors that affect health Determine the relative importance of causes of illness, disability, and death Identify those in the population that have the greatest risk from specific causes of illness Evaluate the effectiveness of health programs and services in improving population health
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what is the Epidemiology Triangle?
host - age - race - sex - genetic profile - previous disease - immune status - religion - customs - occupation - marital status - family background agent - biologic (bacteria, viruses) - chemical (poison, alcohol, smoke) - physical (trauma, radiation, fire) - nutritional (lack, excess) environment - temp, humidity, altitude - crowding, housing, neighborhood - water, milk, food - radiation, pollution, noise
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Epidemiology Key Terms Epidemic or outbreak: Endemic: Pandemic Surveillance Cluster
Epidemic or outbreak: disease occurrence among a population that is more than what is expected in a given time Endemic: disease or condition present among a population at all times; always there Pandemic: a disease or condition that spreads over a wide geographic area and affects an exceptionally large population across regions, maybe worldwide--globally Surveillance: Ongoing systematic collection, analysis, and interpretation of health data needed for planning, implementation, and evaluation of public health practice Cluster: a group of cases in a specific time and place that might be more than expected.
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A public health approach-Public health problems are diverse
surveillance: what is the problem (problem) identify risk factors: what is the cause intervention evaluations: what works implementation: how do you do it (response)
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All of the following illustrate the purpose of epidemiology in public health EXCEPT: A Identifying populations who are at risk for certain diseases B Assessing the effectiveness of interventions C Providing treatment for patients in clinical settings D Determining the importance of the cause of illness Your
C! Providing treatment for patients in clinical settings- Leave it to physician which is what I put randomly LOL
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In March 2021, an outbreak of measles occurred among students at a community college in Boston. This group of cases during this specific time and place is described as a _________________________________.
cluster
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HIV/AIDS is one of the worst global diseases in history. It is a/an___________________.
pandemic
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The Ebola virus in parts of Africa is in excess of what is expected for this region. This virus is a/an______________________.
epidemic (or outbreak) the key is EXCESS; the agent is more than what we want
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Malaria is present in Africa at all times because of the presence of infected mosquitoes. Malaria is ___________________ in Africa
endemic
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Surveillance what is it in PH it is warning system for what Once an outbreak is discovered, what can be done
Epidemiologic surveillance is a major line of defense in protecting the public against disease It is a warning system that alerts communities that something is wrong Once an outbreak is discovered, public health officials can begin to take action to prevent the spread of disease - Immunizations - Isolation of an infected person - Recall of medication or contaminated food
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what are the list of disease thata healthcare provider should report to the public health department does surveillance ever stop
The Federal government has a list of notifiable diseases that a healthcare provider must report to the public health department: Hepatitis B HIV STDs Tuberculosis COVID-19 Surveillance is ongoing and systematic
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Outbreak Investigations what are the steps
Construct a working case definition Perform descriptive epidemiology (Who, Where, When) Implementing control and prevention measures Initiate or maintain surveillance Communicating findings to stakeholders, community etc
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Outbreak Investigation what is step 1? what is the probable case what is confirmed case
Step 1- Construct a working case definition Establish a case definition by using a standard set of criteria Probable Case: Have signs and symptoms but no confirmed laboratory work Confirmed Case: Have signs and symptoms with laboratory confirmation
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Example: Meningococcal disease for outbreak investigation what is a clinical case what is a lab diagnosis what is probable and what is confirmed
Clinical case definition: An illness with sudden onset of fever (>380C and one or more of the following: neck stiffness, altered consciousness, other meningeal signs or petechial or puerperal rash Lab diagnosis: Positive cerebrospinal (CSF) fluid antigen detection or positive culture Case classifications: Suspected: Meets clinical case definition Probable: As suspected case and turbid CSF (with or without positive Gram stain) or ongoing epidemic and epidemiological link to a confirmed case Confirmed: A suspected or probable case with laboratory confirmation
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Outbreak Investigation step 2 what kind of epidemiology is performed how do you suumarize data what does it provide what can be inferred what can it provide clues for what can begn after this what can you establish from this
Step 2- Perform descriptive epidemiology- This step is very important because it will: Summarize data by key demographic variables Provide trends over time, geographic areas and the population affected From this information you can infer the population at risk for the disease Can provide clues about the source, modes of transmission Can begin interventions and preventative measures to control disease Establish epidemic curve-shows magnitude of disease over time
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Outbreak Investigation step 3 & 4 what does step 3 do - what does it control and preventand what is the primary goal - what kinds of things can be done step 4 - once control measures are in place, what must be done
Step 3- Implement control and prevention measures - Control and prevent additional cases is the primary goal. If appropriate measures are known they should be put in place as early as possible. - Masks for respiratory transmission, spraying or bed nets for mosquito transmission Step 4- Initiate or maintain surveillance Once control measures are in place must monitor to see if working or not
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Outbreak investigation step 5 determine what what are examples of these determine what about information what is an example of that identify what what next needs to be controlled
Step 5- Communicate findings Determine who needs to know Local health authorities. Medical community, general public, lawmakers Determine how information will be communicated Oral briefings via news of implementation of control and prevention measures Identify why information needs to be communicated Control spread of illness
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Outbreak Investigation
New regulations may result from the findings Legionnaire's disease led to the development of new regulations worldwide for climate control systems (A/C systems and cleaning requirements) More recent outbreak that led to changes in regulations: - Meningitis outbreak of 2012 from New England Compounding Center (NECC) - Changed continuing education requirements for pharmacists conducting sterile and non-sterile compounding - Owner of pharmacy found guilty on 57 of 96 charges- serving 9 years in prison - Chief pharmacist- charged with 25 counts of second degree murder (found not guilty) found guilty on racketeering charges- Serving 8 years in prison
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Chronic Diseases what can it show links between how does it develop, is there a single cause
Epidemiology is also useful in identifying the causes of some chronic diseases Can show links between the occurrence of disease with exposure to risk factors Chronic diseases develop over time and do not have a single cause Risk factor concept: a particular biologic, lifestyle & social conditions are associated with increased risk for specific chronic diseases
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Heart Disease what was it the first epidemiologic study to do who was in the study what are the Three major risk factors for heart disease are:
Framingham Heart Study - Began collecting data in 1948- still collecting today - Was the first epidemiologic study of a chronic disease - > 5000 healthy, middle-aged subjects in Framingham, MA- examined every 2 years Findings from this study: Three major risk factors for heart disease are: - High cholesterol - Hypertension - Smoking
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heart disease prospective cohort study
In 1971- the study continued to the off-spring of the original study subjects In 2001-2002- the grandchildren of the original study subjects became part of the study This type of study is called prospective cohort study because it follows the subjects through time Guidelines to treat cardiac conditions such as hypertension and dyslipidemia have been developed based upon the knowledge gained in this study
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Heart Disease data
Data from these trials helps us today in medicine for evidence-based recommendations The Framingham Heart Study found: - Weight gain and lack of exercise are associated with high blood pressure and high cholesterol levels therefore increasing the risk of heart disease Expanded studies found; - Effects of quitting smoking - “Good” cholesterol versus “bad” cholesterol” - Alcohol in moderation has beneficial effects
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Lung Cancer studies what are the 2 studies
What link has been associated with lung cancer? Two landmark studies: Doll and Hill (UK) - Death rate from lung cancer was 20 times higher in smokers than in non-smokers - Death from heart attacks was significantly higher in heavy smokers aged 35-54 than in non-smokers Hammond and Horn (US) - Smokers are 10 times more likely to die of lung cancer than non-smokers - Heavy smokers are 2.4 times more likely to die of heart disease than non-smokers
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Case
BW is 59 year old African-American male with atrial fibrillation and hypertension. He currently takes aspirin, lisinopril, hydrochlorothiazide daily. - Lipid panel: TC 201, LDL 160, HDL 30, TG 180, - Blood pressure 170/90 - Smoked 1 pack of cigarettes a day for 30 years What is his ASCVD 10-year risk Score? Lifetime score?
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of epidemiology Summary whatis epidemiology important for what do Epidemiologists investigate what does it provide what is the role in identifying causes of disease what does it want to achieve what do agences build what do they help with
Epidemiology is an important component of the assessment function of public health Epidemiologists investigate epidemics by counting the number of cases and how they are distributed by person, place, and time Epidemiology also provides information on the cause of chronic diseases Epidemiology’s role in identifying causes of disease leads directly and indirectly to prevention and control To achieve improvements in public health: Agencies build on the information from information gathered from epidemiological studies to develop policies They help plan programs aimed at reducing risk and promoting health in the population
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Important Terminology for Chapters 5- 6-7 Epidemiologic Principles and Methods
Case Control Cohort Epidemic curve Incidence Intervention Study Probability Relative Risk Surveillance Bias Confounding variable P-value Significance Statistics
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Conducting studies why are studies conducted
Studies are conducted in an attempt to discover associations between an exposure or risk factor and a health outcome
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Epidemiology Study Types can be either:
can be either: observational or experimental observational can be either: descriptive - who, when, where, hypothesis or analytic - how, tests hypothesis
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Descriptive vs Analytic Epidemiology
Descriptive epidemiology asks - When was the population affected? - Who was affected? Analytic epidemiology asks - How was the population affected? Descriptive epidemiology asks - Where was the population affected? Analytic epidemiology asks - Why was the population affected?
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Distribution who when when where
Who: age, sex, race and economic status When: trends of disease frequency over time (is it increasing?, decreasing?, remaining stable?) When: tracking an outbreak. Use epidemic curves to plot the number of cases over some time. Where: compares disease frequency in different counties, states or countries or other geographic areas. Can also compare urban vs. rural areas
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Distribution what does the info. collected provide and what can determinants be
The information gathered on the distribution of disease gives clues about the determinants of disease. Determinants can be any underlying social, economic, cultural or environmental factors that are responsible for health and disease.
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what are the Three study designs are commonly used in epidemiology (Observational) what experimental studies are used to test for
3 study designs: Cross-sectional Cohort Case-control Experimental studies to test efficacy of medications - Randomized Controlled Studies are used
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Determinants when you have clues, what can you do what can you do with hypothesis what can it do
When you have clues to the determinants of disease you can generate a hypothesis The hypothesis can be tested by formal/systematic epidemiologic studies These can confirm or disprove the hypothesis
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Cross Sectional study what does it analyze why are the subjects selected what does it provide
Analyzes data of variables collected at one given point in time across a sample population or a pre-defined subset. Subjects are selected because they are members of a certain population at a certain period Provides a “snapshot” of exposures and outcomes
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Cohort Study what does it study what type of people does it start with what does it provde are Prospective or retrospective usually short
A study of a group of people, or cohort, followed over time to see how some disease or diseases develop The study typically begins with healthy subjects who are asked about their exposures These studies provide the best information about the causation of disease and the most direct measurement of the risk of developing a disease Prospective or retrospective and can take years to complete
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Cohort Studies what are the advantages and disadvantages
Advantages Can study multiple outcomes Study uncommon & multiple exposures Provides clearer sequence of events Selection bias is not likely Directly calculate disease incidence Disadvantages Expensive & time consuming May take years to complete study Inefficient for rare outcomes or disease with long latent periods Data on some confounding variable may be missing Source of error Loss to follow-up
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Case-Control study what does it compare what are case-patients what are control-patients how do epidemiologists work what are cases and controls compared with how long does it take to do this study how are subjects matched
A study that compares individuals affected by a disease with a comparable group of persons who do not have the disease to determine possible causes or associations Those with the disease or condition are case-patients Those without the disease or condition are control-patients Epidemiologists work backward from the illness or health condition (retrospective in nature) to determine any associations Cases and controls are compared for the presence or absence of one or more specific exposures or risk factors Takes a shorter amount of time to complete All subjects are matched as much as possible (age, race, gender, other factors relative to the disease) match case/experiment patients with those that do not have the disease, one has the disease and one does not have one is retrospective tries to link the disease with exposure
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how to Design of Case-Control Study what does it start with what does it spearate what are done to both groups
start with population separate into cases and controls have both groups each be exposed and not exposed so in total tested 4 groups: 1 exposed and not exposed for case = 2 1 exposed and not exposed for control = 2 2 + 2 = 4
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Case Control Studies advantages and disadvantages
Advantages Can study multiple exposures They are efficient for rare diseases or diseases with a long latency period between exposure and disease manifestation Faster and easier to conduct than other studies Less expensive the more people, the more reliable data Disadvantages Bias can be a source of error Recall Bias Information Bias- will have to remember and they may not be able to recall Reporting bias Selection bias They are inefficient for rare exposures
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Experimental Study what does it deal with what are the types of studies used for what are the two groups that are started with and what will each get what may the two groups be how are subjects assigned into groups what can occur
deals with Randomized Controlled Trials (RCT) These types of studies are used to test new drugs for safety and efficacy before they are approved for marketing Start with two groups: Experimental group-will get the new treatment Control group-may get placebo Can be blinded or double blinded Subjects are randomized into groups Have an intervention occur (subjects given counseling and drug or no counseling with placebo)
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Randomized Controlled Studies what are advanatges and disadvantages
Advantages Convincing Can control for confounders (known and unknown) Disadvantages Very expensive- millions of $$ Artificial environment Ethical issues- like will not do on pregnant women Difficult to conduct logistically
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Measurements used in epidemiology rate PAR Incidence prevalence mortality rate
Rate is the number of cases but this number must be relative to the size of the of the population being studied. Population at risk (PAR): This number should only include people who are potentially susceptible to the disease being studied. Incidence is the rate of new cases of a disease in a defined population over a defined period of time Measures the probability that a healthy person in that PAR will develop that disease during that specific time Incidence-Expresses the risk of becoming ill. Must always include a unit of time- such as cases per 10^ n per day, week, month or year. Prevalence is the total number of cases of a disease existing in a defined population at a specific time Rates change slowly-not useful for epidemiologic studies Useful in assessing social impact of disease-affects planning Prevalence- Estimates the probability of the population being ill at the period of time being studied Prevalence is often expressed as cases per 100 (percentage) or per 1000 population. Mortality rate is the incidence of death per unit of time (usually per year) in a population, which can look at all deaths or a specific cause of death. With COVID, measure how many passed form COVID
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: Measurements of Association how does epidemiology identify association what are the 2 types of measurements used in epidemiology studies
Epidemiology identifies associations between exposures and outcomes Salt intake → Hypertension (direct association) Salt in take → Hypertension → Coronary artery disease (in-direct association) Types of measurements used in epidemiologic studies: Relative Risk Odds Ratio
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Measurements of Association: Relative Risk (RR) what does it measure what ratios does it measure what does RR = 1.0 mean what does RR > 1.0 mean what does RR < 1.0 mean and is it sometimes called where is this typically used
measures: If an association exist, how strong is it? What is the ratio of the risk of disease in exposed individuals to the risk of disease in unexposed individuals? RR = 1.0 = no association between exposure and the disease. Cannot confirm or deny that exposure leads to outcome RR > 1.0= shows a positive association (increased risk from exposure) RR < 1.0 = Shows a negative association (decreased risk from exposure)- sometimes called a “protective effect” Typically used in COHORT (follow a group for a certain time) studies
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Measurement of Association: Odds ratio (OR) what study uses this can it directly calculate the risk? what does OR = 1 OR > 1 OR < 1 mean
What are the odds that the disease will develop in an exposed person? Association of an exposure and a disease Used in case-control studies Can not directly calculate the risk since subjects already started with the disease- it is an approximation of the relative risk OR = 1 no association, OR >1 positive association, OR < 1 negative association
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Measurement of Association: 95% Confidence Interval what is the 95% CI used for what does a high and low CI indicate what is the 95% CI used for Is wide or Narrow CI more reliable what is range includes 1
a range of numbers and we are 95% sure that the true number falls in that range The 95% confidence interval (CI) is used to estimate the precision of the OR (also used in RR). A large CI indicates a low level of precision of the OR, whereas a small CI indicates a higher precision of the OR. In practice, the 95% CI is often used as a proxy for the presence of statistical significance if it does not overlap the null value (e.g. OR=1). Will look like this: RR=3 (95% CI 1.67-4.2); p<0.5 is a range of numbers narrow shows a really high precision and shows more confidence than wide if includes 1 it is not statically significant and we cannot say that there is an association because the true number could be 1 and for OR & RR there is no association 1.67 is higher than 1 so there is a positive assoication, it has to be 1.0 for it to really be 1
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Sources of Error what are confounding variables? what us bias what is selection bias what is recall bas
Confounding variables: Is a factor or explanation that may affect a result or conclusion. Bias- is a systematic error in the design, conduct or analysis of a study that results in a mistaken estimate of an exposure’s effect on the risk of disease. Selection bias: there is an error in choosing the individuals or groups to take part in a study This is often a problem in case-control studies Recall Bias: An error caused by differences in the accuracy or completeness of the recollections retrieved ("recalled") by study participants regarding events or experiences from the past. Is an issue in case-control studies
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P-value what is it what P-value is used in clinical trials what does that number mean are we comfortable with that number, is it that same for physics?
The P-value is the probability that the observed results occurred by chance alone In clinical trials, a p-value of 0.05 is often used This means if the study was conducted 100 times- the result would be the same 95 times and 5 times would have a different result We are comfortable with a 5% error but other disciplines have a much higher p-value (i.e. physics might set a p-value at 0.001)
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Proving Cause and Effect
Epidemiological studies usually speak of risk factors than causes. To make the results of a study stronger it is important to show a cause and effect relationship
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Elements of Cause and Effect what does a study with a lot of subjects lead to The Framingham Heart Study has thousands of participants. This makes the results much more valid than another study with how many subjects what does a stronger association between exposure and disease result in which has a stronger association, an RR of 20 or RR of 1
A study with a large number of subjects is more likely to yield a valid result The Framingham Heart Study has thousands of participants This makes the results much more valid than a study of only 30 subjects The stronger the association measured between the exposure and disease the more likely there is a cause-and-effect relationship A RR of 20 in regards to smoking and lung cancer is a much stronger association than a RR of 1. So 20x more likely to get lung cancer from smoking than if I do not smoke. 20 shows a stronger association
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Elements of Cause and Effect what relationship does exposure and risk have the more exposure equals what what happens if you have a lot of exposure to the disease
Dose-response relationship between exposure and risk of disease The more exposure you have the more likely you are to get the disease. A nurse caring for patients with Avian Influenza compared to a nurse in a calling station answering patient’s questions. LOTS of exposure to the virus more likely to contract the flu than a nurse not exposed to the flu virus. have to get exposure to disease to get the disease
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elements of cause and effect what two things are needed for this
A known biological explanation between exposure and a disease - Is the epidemiological findings consistent with the current biological knowledge? - Rubella causing congenital cataracts Results are consistent with other investigations - Studies conducted in different populations still have similar results - If an association is found it is expected to see the same results within subgroups of the population and in different populations (unless there is a clear reason to expect differently)
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Use in pharmacy practice what kind of medicine is used what studies are used how are studies communicated? do physicians use it?
Evidence-based medicine is used widely today to make sound medical decisions. Pharmacoepidemiology studies can be used in the drug therapy decision process. Studies are published to show that drugs are safe and effective. Physicians use these studies for treatment guidelines.
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What are the rates of physician visits and practicing physicians in the U.S. compared to other nations?
The U.S. has among the lowest rates of physician visits and practicing physicians
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What are the hospital stays of the U.S. & Netherlands compared to other nations? How many beds does the U.S have compared to other nations
hospital stays are shortest in the Netherlands and the U.S. The u.S has among the lowest number of hospital beds
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compared to other countries, how much does the U.S. spend on admin. costs do they spend more or less on LTC than other countries
the U.S spends more on administrative costs but less on long-term healthcare than other wealthy countries
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Subjects with lung cancer are compared to subjects without lung cancer A Cross Sectional B Cohort C Case Control
C case control
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A study of children age 10-16 in a community located near high tension wires for 2 months A Cross Sectional B Cohort C Case Control
B cross-sectional specific pop. at one point in time
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Subjects who have received exercise & nutritional sessions followed for 5 years to measure health outcomes A Cross Sectional B Cohort C Case Control
B cohort Group is followed through time so prospective cohort
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which one is statically significant RR 0.5 p < 0.001 OR 2.5 (95% Cl -2.5 to 5) RR 2.5 (95% Cl 2 to 5) OR 1.5 p = 0.8
p < 0.001 is statically significant OR 2.5 (95% Cl -2.5 to 5) is not because it includes 1 RR 2.5 (95% Cl 2 to 5) is because it does not include 1 OR 1.5 p = 0.8 is more 0.05, has to be less of it to be statistically significant
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endemic
illness that is around all the time disease or condition present among a population at all times
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Epidemic or outbreak:
disease occurrence among a population that is in excess of what is expected in a given time
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Pandemic:
a disease or condition that spreads over a wide geographic area and affects an exceptionally large population across regions, may be worldwide.
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Surveillance:
: Ongoing systematic collection, analysis, and interpretation of health data needed for planning, implementation, and evaluation of public health practice
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chronic disease
develop over time Risk factor concept: a particular biologic, lifestyle & social conditions are associated with increased risk for specific chronic diseases a disease that you have for a long time
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incubation period
the period between exposure to an infection and the appearance of the first symptoms.
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risk factors
characteristics at the biological, psychological, family, community, or cultural level that precede and are associated with a higher likelihood of negative outcomes.
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what do epi curves show what does it allow you to distinguish what does the shape tell you
The epi curve shows the magnitude of the epidemic over time It permits the investigator to distinguish epidemic from endemic disease The shape of the epidemic curve may provide clues about the pattern of spread in the population
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what is an endemic curve what does the horizontal axis show
Epidemic curve (epi curve) shows progression of an outbreak over time The horizontal axis represents the date when a person became ill, also called the date of onset.
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what about the epidemic does the epi curve show you what can it be used for
The curve shows where you are in the course of the epidemic - Still on the upswing, on the down slope, or after the epidemic has ended. The curve can be used for evaluation, answering questions like: - How long did it take for the health department to identify a problem? - Are intervention measures working?
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A similar group of subjects with lung cancer are compared to subjects without lung cancer to determine possible associations Cross-sectional Case-control Cohort
case control case: with lung cancer control: without lung cancer
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Subjects who have received exercise & nutritional sessions are followed for 5 years to measure health outcomes Cross-sectional Case-control Cohort
cohort
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A study of children age 10-16 in a small community located near high tension wires for a total of 2 months Cross-sectional Case-control Cohort
cross sectional
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is the p-value statistically significant? OR 1.83 (95% CI 1.50 to 2.24); p=0.05 RR 1.66 (95% CI 1.37 to 2.00) OR 0.83 (95% CI 0.61 to 1.08 RR 0.87 (95% CI 0.66 to 1.15) RR 2.23; p<0.001
OR 1.83 (95% CI 1.50 to 2.24); p=0.05 - Yes! The 95% CI does not include 1 and the p-value is statistically significant RR 1.66 (95% CI 1.37 to 2.00) - Yes! The 95% CI does not include 1 OR 0.83 (95% CI 0.61 to 1.08) - No! the 95% CI includes the number 1 RR 0.87 (95% CI 0.66 to 1.15) - No! the 95% CI includes the number 1 RR 2.23; p<0.001 - Yes! The p-value is less than 0.05 RR > 1 positive association RR < 1 negative association RR = 1 no association
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cross-sectional vs cohort
both deal with a certain group BUT Cross-sectional - measure at ONE time cohort - measure over a certain period of time (like over 5 years The cross-sectional study has an identical structure to the cohort study except that the exposures and outcomes are measured at the same time (i.e. cross-sectionally), whereas in a cohort study outcomes are typically measured after the exposure/s have been measured (i.e. longitudinally).
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rate
An expression of the frequency with which an event occurs in a defined population the number of cases in a population
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Population Attributable Risk (PAR)
This number should only include people who are potentially susceptible to the disease being studied. the porportion of the incidence (the number of case) of a disease in the population (exposed and nonexposed) that is due to exposure--so the proportion of cases that is due to (or can be attributed to) exposure
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Incidence
the rate of new cases of a disease in a defined population over a defined period Measures the probability that a healthy person in that PAR will develop that disease during that specific time Incidence-Expresses the risk of becoming ill. Must always include a unit of time- such as cases per 10^ n per day, week, month or year
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prevalence
a measure of disease that allows us to determine a person's likelihood of having a disease
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Mortality rate
the incidence of death per unit of time (usually per year) in a population, which can look at all deaths or a specific cause of death. With COVID, measure how many passed form COVID
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prevalence
Rates change slowly-not useful for epidemiologic studies Useful in assessing social impact of disease-affects planning Prevalence- Estimates the probability of the population being ill at the period of time being studied Prevalence is often expressed as cases per 100 (percentage) or per 1000 population.
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prevalence vs incidence both have to do with cases in a population
Incidence is a measure of the number of new cases of a characteristic that develop in a population in a specified time period (the number of new cases in a pop. so 14 people in a population have COVID) prevalence is the proportion of a population who have a specific characteristic in a given time period, regardless of when they first developed the characteristic. (the proportion of cases in a population so 20% of people in a population have COVID)
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prevalence example
You talk to all 200 people in your town on a spring day and find 60 of them have allergy symptoms. The point prevalence of allergies in your town would be 30% or 3 in 10 individuals calculated as: (60 people with allergy symptoms) / (200 people at risk) = 0.3 = 30%
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incidence example
newly identified cases of a disease or condition per population at risk over a specified timeframe. [1] An example of incidence would be 795,000 new strokes in the United States, annually.
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PAR simplified Population Attributable Risk
the proportion of the incidence (the number of case) of a disease in the population that is due to exposure--so the proportion of cases that is due to (or can be attributed to) exposure how many of the cases are actually due to exposure to the agent? OH OKAY GOTCHA!