Vitamins Flashcards Preview

Jonathan's Metabolism > Vitamins > Flashcards

Flashcards in Vitamins Deck (36):
1

List the four fat soluble vitamins

A, D, E, and K

2

What is the biological role of thiamin?

coenzyme in decarboxylation from pyruvate to acetyl CoA
metabolism
nerve function

3

Which food should we eat to get thiamin?

vegemite, wholemeal bread

4

How quickly will we run out of thiamin? What happens if we run out?

2 weeks, and we will get neural deficiency (beriberi)

5

What are the symptoms of Beriberi syndrome?

extreme weakness, paralysis, anemia, wasting

6

What is wet beriberi?

low serum albumin resulting in oedema

7

What is the biological role of riboflavin (B2)

electron carrier (FAD, FMN)
metabolism

8

what are the sources of B2

vegemite, milk/cheese, fortified cereal

9

What's the more common cause of B2 deficiency?

chronic alcoholism

Symptoms are sore tongue and its magenta appearance

10

What is the biological role of Niacin (B3)

coenzyme, electron carrier (NADH, NADPH)
metabolism

11

What is the source of B3

vegemite, wheat bran

12

What are the causes of B3 deficiency?

alcohol
Pellagra (corn-rich diet)

13

What are the 4 symptoms of Pellagra?

dermatitis, diarrhoea, dementia, death

14

What is the biological role of pyridoxine

amino acid metabolism

15

What are the sources of B6?

vegemite, nuts, bananas, fortified cereal

16

What is the biological role of biotin?

transfer CO2
metabolism

17

What are the sources of biotin?

cooked egg yolk
soy beans

18

Why do people get biotin deficiency when eating raw eggs

protein avidin binds strongly to biotin to antagonise its action, but avidin is killed with heat

19

What is the biological role of folate

DNA synthesis

20

What are the sources of folate

green vegetables

21

What is the result of folate deficiency?

macrocytic anaemia, spina bifida, glossitis

22

Vitamin B12 has a role in transalkylation. Which tissue requires this reaction?

blood and nerves

23

What are the sources of B12

meat, egg yolks, cheese

24

What are the symptoms of B12 deficiency?

neurological disorders and pernicious anaemia

25

What is the biological role of Vitamin C

cofactor for collagen synthesis (hydroxylating prolines)
neurotransmitter metabolism
iron absorption
antioxidant

26

How does scurvy cause death

in vitamin C deficiency, arteries lack collagen and can result in micro haemorrhages. Patients can die from internal haemorrhages

27

What is vitamin A derived from?

beta-carotene

28

T/F You get overdose of vitamin A by having too much carotene

False, body only cleaves to make enough vitamin A

29

what's vitamin D derived from?

cholesterol, and requires UV light for synthesis

30

What is the function of vitamin D?

Ca regulation and bone growth

31

What are the conditions due to vitamin D deficiency

kids - rickets
adults - osteomalacia

32

how much calcium is excreted from the kidneys everyday?

1 gram

33

What's the function of vitamin E

antioxidant, linked to inflammation and cell division

34

Which food has high level of vitamin E

seed oil

35

What is the function of vitamin K

coagulation cascade, activate thrombin

36

Where can we get vitamin K?

out gut flora usually makes enough