Wbc

Question 1

What are the two agranulocyte

Answer 1

Lymphocyte, monocyte

Question 2

What is the function of the neutrophil

Answer 2

First responder against microbes

Question 3

What does neutrophils in tissue cause

Answer 3

Pus

Question 4

When neutrophils leave circulation how long did they stay in blood

Answer 4

10 hours then go into tissues

Question 5

How long do neutrophils survive in tissues

Answer 5

1 to 4 days then undergo apoptosis

Question 6

What can cause prolonged neutrophil lifespan

Answer 6

Cushing’s disease or steroid therapy

Question 7

How Do neutrophils migrate to tissue

Answer 7

Diapedesis

Question 8

How do dogs react

Answer 8

Physiologic neutrophilia

Question 9

How do cats react

Answer 9

Physiologic lymphocytosis

Question 10

What are the signs of a regenerative left shift

Answer 10

Leukocytosis and more mature neutrophils then immature

Question 11

What are the signs of a degenerative left shift

Answer 11

Child soldiers. Less mature than immature and a leukopenia

Question 12

What are the names of the immature neutrophils

Answer 12

Band neutrophils, myelocyte, metamyelocyte

Question 13

What is a hypersegmented neutrophils

Answer 13

Neutrophil with five or more lobes

Question 14

What are five types of toxic neutrophil

Answer 14

Cytoplasmic basophilia, cytoplasmic vacuolation, Dohle bodies, cytoplasmic granulation, Bizzarre nuclear configuration

Question 15

What are Dohle bodies

Answer 15

Basophilic leftover endoplasmic reticulum. We see them when there is a rapid turnover of cells. Often seen together with toxic granulation

Question 16

What is toxic granulation

Answer 16

Found in severe inflammatory states. Thought to be due to impaired cytoplasmic maturation in effort to rapidly generate large numbers of granulocytes

Question 17

What are some intracytoplasmic inclusions in the neutrophil due to

Answer 17

Canine distemper. Ehrlichia

Question 18

What is Peter huet anomolye

Answer 18

Hypersegmentation of all granuolocytic nuclei

Question 19

What is chediak higashi syndrome

Answer 19

Inherited disease

Fused granules

Question 20

What is the Birman cat neutrophil anomaly

Answer 20

Neutrophils have eosinophilic granules

Question 21

What is pelger huet anomaly

Answer 21

Is inherited as an incomplete dominant. Homozygous usually die in utero. Mainly in Australian shepherd

Question 22

What are 3 causes of neutrophilia p

Answer 22

Physiologic or epinephrine induced
Corticosteroids or stress induced
Acute inflammation

Question 23

What is neutrophilia

Answer 23

Counts exceed 12,000-13,000/ul

Question 24

What is neutropenia

Answer 24

In dogs and cats, when the absolute count is less than 3000-4000 ul

Question 25

How long does it take for bone marrow to generate an eosinophil

Answer 25

5-7 days

Question 26

What are the functions of eosinophils

Answer 26

Systemic hypersensitivity reactions | Elimination of parasites

Question 27

When do you see eosinopenia

Answer 27

When cortisol reduces the eosinophils

Question 28

How long do basophils circulate the blood

Answer 28

For a few hours

Question 29

How long do basophils live in the tissues

Answer 29

For a few weeks

Question 30

What do basophil granules contain

Answer 30

histamine and heparin

Question 31

what are monocytes

Answer 31

released into peripheral blood as immature cells and are transported to tissues where they can differentiate into macrophages, epitheloid cells, multinucleated inflammatory cells

Question 32

what are the functions of the macrophages

Answer 32

phagocytosis inflammatory response antigen processing regulation of body iron stores

Question 33

monocytosis indicates

Answer 33

presence of inflammation demand for phagocytosis tissue necrosis chronic inflammation

Question 34

What are the three types of granulocytes

Answer 34

Neutrophils, basophils, eosinophils

Question 35

What is the percent division of lymphocytes

Answer 35

70% Are T-lymphocytes and 30% are B lymphocytes

Question 36

Are the two different types of lymphocytes distinguishable on the smear

Answer 36

No it is indistinguishable

Question 37

What is the function of the lymphocyte

Answer 37

They're the cells of the specific immune system

Question 38

What do b- lymphocytes differentiate into

Answer 38

Into plasma cells which produce antibodies (humoral immunity)

Question 39

What do T lymphocytes do

Answer 39

Responsible for cellular immunity through the formation and release of molecules known as cytokines

Question 40

What is lymphopenia

Answer 40

Reduction in the number of circulating lymphocytes

Question 41

What is lymphopenia caused by

Answer 41

Viral infections, high circulating levels of glucocorticoids, cancer

Question 42

What is physiologic lymphocytosis in cats cause by

Answer 42

Excitement

Question 43

What is lymphocytosis do to antigenic stimulation

Answer 43

When inflammatory conditions are often associated with antigenic stimulation lymphocytosis an elevated globulins may result

Question 44

What is lymphocytosis generally accompanied by

Answer 44

Marked non-regenerative anemia. Thrombocytopenia, neutropenia.

Question 45

Describe atypical lymphocytes

Answer 45

Abnormal finding present in both infectious and neoplastic diseases