Week 6.1 Clinical Presentation of Hepatic Diseases Flashcards Preview

Advanced Clinical Practice Complex Patient > Week 6.1 Clinical Presentation of Hepatic Diseases > Flashcards

Flashcards in Week 6.1 Clinical Presentation of Hepatic Diseases Deck (17)
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1

what are the major functions of the liver

-produce albumin and other plasma proteins
-bile production
-conversion and excretion of bilirubin
-produce clotting factor
-store vitamins
-immune for the gut

2

what is the liver and gallbladder primary pain pattern

mid-epigastrium and the right upper quadrant of the abdomen

3

secondary referral pattern of the liver

T7-T10, right shoulder

4

secondary referral pattern of the gallbladder

right shoulder, right inter scapular (T4/5-T8), right subscapular

5

what are some gastrointestinal symptoms that point to hepatic disease

nausea, vomiting, diarrhea, constipation, heartburn

6

what does stool and urine look like with hepatic disease

dark urine and light pale stool

7

what part of the abdomen will you get pain with hepatic disease

the right upper quadrant

8

what skin changes are associated with hepatic disease

jaundice,
bruising,
spider angioma,
palmar erythema

9

what are the neurologic things involved with hepatic disease

confusion
sleep disturbances
muscle tremors
hyperactive reflexes
asterixis (clonus at the wrist)

10

TF: you can get MSK pain, edema and ascites with hepatic disease

true

11

what is portal hypertension

increased venous blood pressure in the portal vein, over 6mmHg

12

when is portal HTN the most common

cirrhosis

13

describe the process portal HTN has

increased pressure combines with inter hepatic vasoconstriction, secondary to decreased nitric oxide release with alterations in the architecture of the liver, and increased the pressure in the veins, so venous flow backs up to the spleen, stomach, esophagus, umbilicus

14

what is cirrhosis

progressive loss of normal tissue replaced with fibrous and nodular regeneration, permanent disruption of hepatic tissue

15

what are the signs and symptoms of cirrhosis

fatigue, weight loss, jaundice, coagulopathies, loss of ability to metabolize drugs and hypoalbuminemia

16

what two things most commonly cause cirrhosis

Hep C and alcohol abuse

17

what does Cirrhosis interfere with

ability of liver to process AA, carbs, lipids, meds, toxins,
metabolizing things,
producing clotting factors
storage of glycogen