Week 3.4 Autoimmune Pathologies Flashcards Preview

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Flashcards in Week 3.4 Autoimmune Pathologies Deck (32)
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1

what is SLE

systemic Lupus erythematosis

2

give an overview of the condition

AA and latino and asian women, aged 15 to 45, with women being 9-10x more likely than men

3

is there a cure for SLE

no

4

how do you self manage SLE

avoid exposure to sunlight
avoid smoking
stress management
prolonged rest at night (12 hours)
regular exercise

5

what are signs and symptoms of SLE

joint inflammation, kidney disease, skin rashes, fatigue, muscle pain, fever, loss of hair, Raynaud's disease, seizures, sensitivity to the sun, swelling (edema in the legs or around the eyes)

6

SLE may also affect

heart, lungs, blood and brain

7

how do you diagnose SLE

blood tests and tissue biopsy

8

how do you treat SLE

corticosteroid creams,
NSAIDs,
antimalarial medications,
corticosteroid pills or IV

9

is SLE a medical emergency

no, but you need a consultation,

10

how do you do PT for a patient with SLE

manage their energy levels, ask them how they feel because they will often be fatigued

11

what is dermatomyositis

pink cheeks
purple hue over the eyelids
red skin rashes (elbows, knuckles, knees)
muscle inflammation, weakness and ashiness.

12

what happens to symptoms over time with dermatomyositis

flu like symptoms, with fever and chills and symptoms getting worse over time, to the point that they cannot stand or climb stairs

13

what is the prognosis of dermatomyositis

good, if detected early, treatment will improve outcomes. Rarely recurrent, but you may need meds for up to 2 years

14

how might dermatomyositis present

skin manifestation in the absence of muscle weakness, and subtle skin manifestations like subtle erythema

15

how do you differential between lupus and dermatomyositis

lupus spares the naso- labial region, and in dermatomyositis, you have it every where, including the nose and mouth area.

16

what is scleroderma

hardening of the skin that affects different body parts

17

what is the cause an prognosis of scleroderma

cause is unknown, prognosis is no cure

18

what is the incidence of scleroderma

localized form in child
systemic in adults
women more common (4:1)
genetic
age 25-55

19

how do you manage scleroderma

medications are greatly variable

20

how do you handle scleroderma

prompt referral, minimize symptoms and reduce irreversible damage

21

how can you tell if you have limited systemic scleroderma

CREST
C: calcinosis
R: Raynaud
E: esophageal dysfunction
S: Sclerodactyly (hardening of the skin and hands that cause the fingers to curl in like claws)
T: telangiectasia (widened venules that cause red lines on the skin, like webs)

22

how do you diagnose scleroderma

blood test and other test that check organs and skin

23

what pulmonary condition can you get with scleroderma

pulmonary HTN with SOB

24

What is psoriatic disorder

speeds up the life cycle of skin cells (get rapidly appearing scales and patches) IDIOPATHIC.

25

what are comorbidites with psoriatic disease

autoimmune thyroid disease, diabetes, metabolic syndrome and psoriatic arthritis

26

what are the signs and symptoms of psoriatic disease

-red patches of the skin, covered with thigh and silvery scales
-small scaling spots
-dry cracked skin that bleeds
-itching burning and soreness
-thickened or pitted or ridged nails
-swollen and stiff joints

27

how does psoriatic disease manifest in the clinic

-discomfort and pain,
-difficulty with routine tasks
-concern about the patients skin
-joint pain, swelling, inability to do ADLs

28

what predisposes you to psoratic disease

-infection (strep or skin infections)
-injury to the skin, cut scrape, bug bite, severe burn
-stress
-smoking
-alcohol consumption
-Vit D deficiency
-certain meds (lithium)

29

what is lithium prescribed for

bipolar disorders, HBP, beta blockers, antimalarial drugs, and iodides.

30

how do you manage psoriatic disease

diet, exercise, weight control, avoid smoking, meds, monitor for depression