Flashcards in White Blood Cells Deck (92):
Increase of wbcs count is called?
Decrease of all wbc count is called?
General function of wbc?
Control inflammation, control bacteria, provide Immunity, help blood clot or help destroy clots and unwanted clots
What is a white blood cell estimate?
40 power, count number of wbcs per field for ten fields, divide total from 10 fields by 10, multiply by 2000=== wbc/microliter (uL)
What is a myloblast and promyelocyte?
A large cell with blue cytoplasm and granules
Three types of granulocytes?
Eosinophils, neutrophil, basophils
Difference between by locate and metmyelocyte?
Metmyelocyte is normal size with a more abundant cytoplasm, normal size nucleus with chromatin
Most common immature cell we see in dogs?
Horseshoe shape neutrophil.
Has 3-5 lobes neutrophil
A mature neutrophil
Where are neutrophils produced then stored?
What happens in the neutrophil proliferating pool.
What happens in the neutrophil maturation pool?
Maturing not dividing
What is stored in the storage pool?
What is mnp?
Marginal neutrophil pool- stuck to walls, waiting to help
What is found in the circulating neutrophil pool?
On the look out for bad things
First line of defense.
Neutrophils in tissues
How do neutrophils rid the body of bad things?
Phago and pino cytosis
Number one cell in circulating blood in cats and dogs.
Segmented neutrophil (mature)
Life span of mature neutrophil.
The most common Immature cell in dogs?
Greater than 5% band cells after your final count (lots of Immature cell)
Why do left shifts happen?
Increased need for neutrophils
More than five segments.
Hyper segmented (right shift)
Why do we see hypersegmentstion?
We left it in a coagulant for too long, b12 deficiency
Causes of neutrophilia?
Muscle activity, bacterial infections, leukemia types
Causes of neutropenia?
Viral infection, bacteria infections, nutritional deficiencies
Where are lymphocytes found.
In the pleuripotent cell
Second most common cell in circulating blood?
Two types of lymphocytes?
Small and medium/large
Round cell, smaller than neutrophils, round to oval nucleus.
Bizarre shaped lymphocytes
Small lymphocytes can we confused with....
Functions of lymphocytes?
T cells- memory cells, B cells- immune surveillance
Third or fourth most common cell in circulating blood?
Functions of monocytes?
Provide immunity, "garbage eater"
Once a monocytes leaves the bloodstream what is it called?
What causes mono cytosis?
Inflammatory diseases, infections, fevers, obstructions,
Third or fourth most common cell in blood?
Where are eosinophils found?
Intestinal lining, uterus, respiratory tract, skin
For each eo in the blood, how many are in the tissue?
What causes eosinophilia?
Rare cell found in circulating blood?
Most common in horses.
Causes of basophilia?
Heartworm, allergies, cushings, leukemia
Difference between eosinophils and basophils?
Basophils are darker
Difference between monocytes and lymphocytes?
Monos are larger usually, monos have vacuoles and appear fluffier
Normal white count.
Production of white blood cells
Production of wbc
Neutrophils have what color granules?
What color granules do basophils have?
What color granules do eosinophils have?
What are agranulocytes?
Where do white blood cells come from?
Where do wbcs perform their job?
What do white blood cells do?
Find inflammation, find infection, provide immunity, help destroy clots, prevents or destroys abnormal or unwanted cells
What does a band neutrophil look like?
What is a right shift?
A lot of old neutrophils
Hypersegmentation can be caused from....
Not making our slide right away --- old blood
After lymphocytes mature, they can become....
T cells or B cells
What do T cells do?
They are the memory cells- create anitbodies
How long can T cells live?
How long do B cells live?
This type of cell has a very large nucleus.
The only cells that we should worry if there is a decrease.
An abnormal finding of more immature neutrophils called bands.
What causes a left shift?
Severe inflammatory diseases
Often seen when there is a left shift.
Toxic change could be...
Increased basophilia, cytoplasmic foaminess, Dohle bodies in the cytoplasm
What color appears more prevalent during toxic change?
He nucleus and the cytoplasm are not maturing at the same speed.
Case of hypersegmentstion.
Two causes of right shift.
Problem with blood smear, cells stay in the circulatory system too long
Can be irregularly shaped lymphocytes.
Looks like a reactive lymphocytes.
Can be seen with severe infections.
Bacteria within the cells
Difference between myelocyte and metamyelocyte?
Metamyelocyte is more mature, you can tell what it'll be
Normal dog neutrophil count.
Normal dog banded neutrophil count.
Normal dog lymphocyte count.
Normal dog monocyte count.
Normal dog eosinophil count?
Normal cat neutrophil count.
Normal cat banded neutrophil count.
Normal cat lymphocyte count.
Normal cat monocyte count.
Normal cat eosinophil count.