Flashcards in Coagulation And Thrombocytes Deck (34)
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1
Stages of platelet hematopoiesis?
Megakaryoblast, promegakaryocyte, megakaryocyte, platelet
2
Made of lit pink cytoplasm and distinct purple granules
Platelets
3
Large platelets (immature)
Macro platelets
4
Three main functions of platelets?
Clotting, preserve capillary walls, transport substances for clotting, and for constriction and dilation of blood vessels
5
Are platelets larger or smaller than RBCs?
Smaller
6
Platelets in ______ vary in size, shape and clumping
Cats
7
Platelets in _____ are relatively uniform in size.
Dogs
8
Macro platelets are normal in....
Cats
9
What do macro platelets indicate in dogs?
Increased platelet use and a need for increased platelet production
10
Normal platelet value for dogs.
150,000 plts/uL - 450,000 plts/uL
11
Normal platelet values for cats.
200,000 plts/uL- 600,000 plts/uL
12
Variation in the size of platelets.
Pleomorphic
13
Cannot stop bleeding at this platelet count number.
50,000 plts/uL
14
Increased of platelets.
Thrombocytosis
15
Two causes of Thrombocytosis?
Injury/trauma/infection or steroids/splenectomy
16
Decrease in number of platelets.
Thrombocytopenia
17
Three main causes of thrombocytopenia?
Hormone disorder, disorders of platelet distribution, vitamin b12 injection
18
Method one of platelet count.
Viewing 10 fields, averaging the fields and reporting them.
19
Normal platelet per field?
7-10 platelets/hpf
20
Method two ***** of platelet count?
Count and record in ten fields, average them, and times by 15,000 = platelets per microliter
21
Cannot accurately count_____ platelets.
Clumped
22
Small pinpoint hemorrhages.
Pettichia
23
Blotches of hemmorage (usually abdomen)
Echymosis
24
Visible bleeding.
Frank
25
Hidden bleeding,
Occult bleeding
26
Large amounts of blood
Profuse bleeding
27
Steps of clotting?
1. Platelets plug, 2. Clotting factors reinforce plug, 3. Fibrin web acts like glue, 4. Other cells reinforce web
28
Extrinsic
PT
29
Intrinsic
PTT
30