Flashcards in Coagulation And Thrombocytes Deck (34)
Stages of platelet hematopoiesis?
Megakaryoblast, promegakaryocyte, megakaryocyte, platelet
Made of lit pink cytoplasm and distinct purple granules
Large platelets (immature)
Three main functions of platelets?
Clotting, preserve capillary walls, transport substances for clotting, and for constriction and dilation of blood vessels
Are platelets larger or smaller than RBCs?
Platelets in ______ vary in size, shape and clumping
Platelets in _____ are relatively uniform in size.
Macro platelets are normal in....
What do macro platelets indicate in dogs?
Increased platelet use and a need for increased platelet production
Normal platelet value for dogs.
150,000 plts/uL - 450,000 plts/uL
Normal platelet values for cats.
200,000 plts/uL- 600,000 plts/uL
Variation in the size of platelets.
Cannot stop bleeding at this platelet count number.
Increased of platelets.
Two causes of Thrombocytosis?
Injury/trauma/infection or steroids/splenectomy
Decrease in number of platelets.
Three main causes of thrombocytopenia?
Hormone disorder, disorders of platelet distribution, vitamin b12 injection
Method one of platelet count.
Viewing 10 fields, averaging the fields and reporting them.
Normal platelet per field?
Method two ***** of platelet count?
Count and record in ten fields, average them, and times by 15,000 = platelets per microliter
Cannot accurately count_____ platelets.
Small pinpoint hemorrhages.
Blotches of hemmorage (usually abdomen)
Large amounts of blood
Steps of clotting?
1. Platelets plug, 2. Clotting factors reinforce plug, 3. Fibrin web acts like glue, 4. Other cells reinforce web