02.Pigmented_Lesions_Tests Flashcards

(16 cards)

1
Q

A patient presents with uniform brown pigmentation of the gingiva with no other symptoms.
Which of the following diagnoses best fits this presentation?
A. Melanoplakia (Physiologic Pigmentation)
B. Smoker’s Melanosis
C. Melanotic Macule
D. Intramucosal Nevus

A

A - Melanoplakia (Physiologic Pigmentation): racial or physiological melanin deposition

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2
Q

A long-term smoker shows diffuse brownish staining on the anterior gingiva.
Which of the following diagnoses best fits this presentation?
A. Melanotic Macule
B. Smoker’s Melanosis
C. Intramucosal Nevus
D. Blue Nevus

A

B - Smoker’s Melanosis: melanin deposition due to tobacco smoking

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3
Q

A solitary dark brown macule on the lower lip discovered during routine exam.
Which of the following diagnoses best fits this presentation?
A. Intramucosal Nevus
B. Blue Nevus
C. Melanotic Macule
D. Compound Nevus

A

C - Melanotic Macule: focal melanin hyperpigmentation on lip or oral mucosa

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4
Q

A small, raised brown papule on the buccal mucosa with nevus cell clusters in epithelium.
Which of the following diagnoses best fits this presentation?
A. Blue Nevus
B. Compound Nevus
C. Junctional Nevus
D. Intramucosal Nevus

A

D - Intramucosal Nevus: nevus cells within oral mucosal epithelium

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5
Q

A flat blue-black lesion on the palate that remains unchanged over years.
Which of the following diagnoses best fits this presentation?
A. Blue Nevus
B. Compound Nevus
C. Junctional Nevus
D. Intradermal Nevus

A

A - Blue Nevus: dermal melanocytes causing blue lesion

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6
Q

A pigmented lesion on the tongue with both junctional and intramucosal nevus features histologically.
Which of the following diagnoses best fits this presentation?
A. Junctional Nevus
B. Compound Nevus
C. Intradermal Nevus
D. Peutz–Jeghers Syndrome

A

B - Compound Nevus: junctional and intramucosal nevus components

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7
Q

A flat brown lesion at the mucosal-epithelial junction of the lip vermilion.
Which of the following diagnoses best fits this presentation?
A. Intradermal Nevus
B. Peutz–Jeghers Syndrome
C. Junctional Nevus
D. McCune–Albright Syndrome

A

C - Junctional Nevus: nevus cells at junction of epithelium and connective tissue

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8
Q

A raised tan papule in the oral cavity composed of nevus cells in the connective tissue.
Which of the following diagnoses best fits this presentation?
A. Peutz–Jeghers Syndrome
B. McCune–Albright Syndrome
C. Addison’s Disease
D. Intradermal Nevus

A

D - Intradermal Nevus: nevus cells within connective tissue layer

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9
Q

A young patient has dark spots on lips and a history of gastrointestinal polyps.
Which of the following diagnoses best fits this presentation?
A. Peutz–Jeghers Syndrome
B. McCune–Albright Syndrome
C. Addison’s Disease
D. Amalgam Tattoo

A

A - Peutz–Jeghers Syndrome: mucocutaneous pigmentation with intestinal polyps

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10
Q

A child with endocrine abnormalities and large café-au-lait spots on the oral mucosa.
Which of the following diagnoses best fits this presentation?
A. Addison’s Disease
B. McCune–Albright Syndrome
C. Amalgam Tattoo
D. Heavy Metal Ingestion

A

B - McCune–Albright Syndrome: café-au-lait spots with endocrine abnormalities

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11
Q

A patient with fatigue and hypotension shows diffuse oral mucosal hyperpigmentation.
Which of the following diagnoses best fits this presentation?
A. Amalgam Tattoo
B. Heavy Metal Ingestion
C. Addison’s Disease
D. Drug-induced Pigmentation (Minocycline)

A

C - Addison’s Disease: adrenal insufficiency with mucosal hyperpigmentation

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12
Q

A localized blue-black lesion adjacent to a legacy amalgam restoration.
Which of the following diagnoses best fits this presentation?
A. Heavy Metal Ingestion
B. Drug-induced Pigmentation (Minocycline)
C. Drug-induced Pigmentation (Chloroquine)
D. Amalgam Tattoo

A

D - Amalgam Tattoo: implantation of amalgam particles causing blue-black stain

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13
Q

A patient with occupational lead exposure has bluish discoloration of the gingiva.
Which of the following diagnoses best fits this presentation?
A. Heavy Metal Ingestion
B. Drug-induced Pigmentation (Minocycline)
C. Drug-induced Pigmentation (Chloroquine)
D. B-K Mole Syndrome

A

A - Heavy Metal Ingestion: systemic metal toxicity causing oral pigmentation

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14
Q

A patient on long-term minocycline therapy develops gray-blue pigmentation of the oral mucosa.
Which of the following diagnoses best fits this presentation?
A. Drug-induced Pigmentation (Chloroquine)
B. Drug-induced Pigmentation (Minocycline)
C. B-K Mole Syndrome
D. Melanoplakia (Physiologic Pigmentation)

A

B - Drug-induced Pigmentation (Minocycline): minocycline-associated gray-blue discoloration

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15
Q

A patient treated with chloroquine for malaria shows dark pigmentation of the inner cheeks.
Which of the following diagnoses best fits this presentation?
A. B-K Mole Syndrome
B. Melanoplakia (Physiologic Pigmentation)
C. Drug-induced Pigmentation (Chloroquine)
D. Smoker’s Melanosis

A

C - Drug-induced Pigmentation (Chloroquine): chloroquine-induced retinal and mucosal pigmentation

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16
Q

A patient with multiple dysplastic nevi on the skin and oral mucosa, family history of melanoma.
Which of the following diagnoses best fits this presentation?
A. Melanoplakia (Physiologic Pigmentation)
B. Smoker’s Melanosis
C. Melanotic Macule
D. B-K Mole Syndrome

A

D - B-K Mole Syndrome: familial dysplastic nevus with melanoma risk