Antiplatelets

Question 1

Common Facts

Answer 1

Commonly used to treat: myocardial infarction (MI, heart attack), stroke
Common adverse reactions: bleeding- signs of internal bleeding are black, tarry stools, blood in vomit or urine, red or purple spots on skin
Notes: interactions with many over-the-counter (OTC) products

Question 2

Mechanism of Action

Answer 2

Interfere with clot formation process

Question 3

Aggrenox

Answer 3

Generic name: dipyridamole+ASA
Capsules: 200mg dipyridamole+25mg ASA
Commonly dosed BID
Auxiliary label: Take with food
Must be dispensed in its original container

Question 4

Aspirin

Answer 4

Generic name: acetylsalicylic acid (ASA)
Tablets: 80mg chewable, 81mg
Commonly dosed once daily
Note: there are additional strengths of ASA available that are typically used for pain relief (325mg, 650mg)
Auxiliary labels: Take with food
-Avoid NSAIDs and other products containing ASA

Question 5

Persantine

Answer 5

Generic name: dipyridamole
Tablets and injections available
Auxiliary label: take on an empty stomach

Question 6

Plavix

Answer 6

Generic name: clopidogrel
Tablets: 75mg, 300mg
Note: 300mg tables are not covered by ODB

Question 7

Ticlid

Answer 7

Generic name: ticlopidine
Tablets: 250mg
Auxiliary label: take with food

Question 8

Brilinta

Answer 8

Generic name: ticagrelor
Tablets: 90mg
Auxiliary label: do not discontinue