Short Acting Beta (B2) Adrenergic Agonists (SABA)

Question 1

Common Facts

Answer 1

Common name: bronchodilators
Commonly used to treat: asthma
Common adverse reaction: palpitations, tachycardia, nervousness
Common auxiliary labels: shake well before use (for most metered-dose inhalers), do not exceed recommended dose (on all SABAs)

Question 2

Mechanism of Action

Answer 2

Bind to beta (B2) receptors
Relax bronchial smooth muscle
Reverse bronchospasm and open airways
Notes: rapid onset of action
-short duration of action (effects last 2-6 hours)
-“rescue” inhalers-used when individual is having asthma attack to open airways

Question 3

Airomir, Ventolin

Answer 3

Generic name: salbutamol
Metered Dose Inhaler (MDI)-100mcg per dose (1 dose=1 puff or inhalation)
Commonly dosed: 1-2 puffs every 4-6 hours
Nebules

Question 4

Bricanyl

Answer 4

Generic name: terbutaline

Turbuhaler: 0.5mg per dose