Anticoagulants

Question 1

Common Facts

Answer 1

Commonly used to treat: myocardial infarction (MI, heart attack)
Stroke
Common adverse reaction: bleeding
Common auxiliary labels: avoid ASA, NSAIDs, and OTC’s without medical supervision

Question 2

Mechanism of Action

Answer 2

Inhibit clotting factors and prevent clot formation

Question 3

Arixtra

Answer 3

Generic name: fondaparinux

Prefilled injectable syringes

Question 4

Coumadin

Answer 4

Generic name: warfarin
Tablets: 1mg, 2mg, 2.5mg, 3mg, 4mg, 5mg, 10mg
Commonly dosed daily (some patients take a few days each week)
Note: overdose treated with Vitamin K

Question 5

Fragmin

Answer 5

Generic name: Dalteparin

Prefilled injectable syringes

Question 6

Hepalean

Answer 6

Generic name: Heparin
Prefilled injectable syringes (“Heparin Flush”)
Solution for injection (vials)
Note: overdose treated with protamine sulfate

Question 7

Innohep

Answer 7

Generic name: tinzaparin

Solution for injection

Question 8

Lovenox

Answer 8

Generic name: enoxaparin
Prefilled injectable syringes
Solution for injection
Commonly dosed every 12 hours or every 24 hours