Alpha (A) Adrenergic Antagonists

Question 1

Common Facts

Answer 1

Common name: alpha (A) blockers
Common ending: -osin
Commonly used to treat: BPH (benign prostatic hyperplasia)
Common adverse reaction: postural hypotension, dizziness, weakness, fatigue, tachycardia
Common doses: dosed once daily

Question 2

Mechanism of Action

Answer 2

Bind to alpha adrenergic receptor sites
Blocks vasoconstriction
Relaxes prostate and bladder smooth muscles
Reduces urethral resistance
Improves urine flow

Question 3

Cardura

Answer 3

Generic name: doxazosin

Tablets: 1mg, 2mg, 4mg

Question 4

Flomax

Answer 4

Generic name: tamsulosin
Capsules and tablets: 0.4mg
Extended release
Auxiliary label: swallow whole; do not crush or chew

Question 5

Hytrin

Answer 5

Generic name: terazosin

Tablets: 1mg, 2mg, 5mg, 10mg

Question 6

Rapaflo

Answer 6

Generic name: silodosin

Capsules: 4mg, 8mg