Proton Pump Inhibitors

Question 1

Common Facts

Answer 1

Common name: PPIs
Common ending: -prazole
Commonly used to treat: GERD (gastroesophageal Reflux Disease); Acid reflux

Question 2

Mechanism of Action

Answer 2

Decrease levels of gastric acid by interfering with the final step in production of gastric acid
Notes: inhibits the proton pump

Question 3

Dexilant

Answer 3

Generic name: dexlansoprazole
Delayed release capsules: 30mg, 60mg
Not covered by ODB

Question 4

Losec

Answer 4

Generic name: omeprazole
Tablets and capsules: 10mg, 20mg, 40mg
LU required for ODB coverage

Question 5

Nexium

Answer 5

Generic name: esomeprazole
Tablets: 20mg, 40mg
Not covered by ODB (off-formulary interchangeable)

Question 6

Pantoloc

Answer 6

Generic name: pantoprazole sodium
Tablets: 20mg, 40mg
LU required for ODB coverage

Question 7

Pariet

Answer 7

Generic name: rabeprazole

Tablets: 10mg, 20mg

Question 8

Prevacid

Answer 8

Generic name: lansoprazole
Capsules and Fast-Tabs: 15mg, 30mg
LU required for ODB coverage