What names are given to SCC-in-situ of the penis?
Erythroplasia of Queryat (glans and shaft)
Bowen's disease (everything else)
What does SCC-in-situ of the penis look like?
Red, velvety plaque
SCC occurs in men who are ___.
What virus is associated with SCC of the penis?
HPV type 16
Is SCC of the penis common in the UK?
What are risk factors for penile SCC?
Aged 20 - 35
HPV type 16
What is a common disorder affecting men over the age of 50?
Benign prostatic hyperplasia (BPH)
What causes BPH?
Imbalance between testosterone (decreases) and oestrogen (excess) levels
What urinary problems does BPH cause?
What group of symptoms are collectively called prostatism?
Hesitancy, slow flow and incontinence are collectively called ___.
What happens to the bladder muscle in BPH?
Forms diverticulae (which stones can lodge in)
What are complications caused by the obstruction in BPH?
How is BPH managed?
5alpha reductase inhibitors (finasteride)
Does BPH lead to prostate cancer?
Not for sure
But people who develop prostate cancer CAN have BPH
What does BPH look like on biopsy?
Stromal and glandular hypertrophy
What is the most common cancer in men in the UK?
When do men tend to get prostate cancer?
People with a ___ history of prostate cancer are more likely to develop it.
Which local organs can prostate cancer spread to?
What is prostate cancer notorious for spreading to?
What process does metastatic prostate cancer cause in bone?
whereas most other cancers cause osteolysis
What are the investigations for
b) suspected metastatic
a) PR exam, blood PSA, prostate biopsy
b) CT everything, bone scans
Does an elevated PSA mean prostate cancer?
No, lots of other reasons
But if gradually, consistently increasing then probably prostate cancer
are used to treat prostate cancer?
a) LHRH agonists, anti-androgen
What is the prognosis of testicular cancer?
What is a big risk factor for testicular cancer?
Is testicular cancer painful?
No, usually presents as PAINLESS TESTICULAR LUMP
What is an endocrine symptom associated with testicular cancer?
What are two germ cell tumours of the testicle?