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Pharmac > Heavy Metals and Metallic Poisoning > Flashcards

Heavy Metals and Metallic Poisoning Flashcards

1
Q

There are two types of inorganic lead poisoning

A

Acute
Chronic

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2
Q

Features of Acute lead poisoning

A

Severe intestinal distress that progresses to marked CNS abnormality

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3
Q

Disorders that stimulate lead poisoning

A

Appendicitis
Peptic Ulcer
Pancreatitis

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4
Q

What is Plumbism

A

Range of toxic syndrome due to chronic lead poisoning

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5
Q

What is Erethism

A

Syndrome resulting from mercury poisoning characterised by insomnia, memory loss, excitability and delirium

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6
Q

Organic lead poisoning is caused by

A

Tetraethyl lead
Tetramethyl lead

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7
Q

Symptoms of organic lead poisoning

A

Hallucination
Insomnia
Headache
Irritability

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8
Q

Steps In management of inorganic lead poisoning

A

Immediate termination of exposure and use of chelation therapy

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9
Q

Severe intoxication of inorganic lead is treated with

A

IV infusion of calcium disodium edetate 8mg/kg

Dimercaprol 2.5mg/kg for childern

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10
Q

Steps In management of organic lead poisoning

A

Decontaminating the skin and preventing further exposure

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11
Q

The two major sources of arsenic poisoning

A

Coal burning power plants
Smelters

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12
Q

The chemical forms of arsenic of toxicology importance

A

Elemental arsenic
Inorganic arsenic
Organic arsenic
Arsin gas

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13
Q

Medical uses of arsenic

A

I. Therapeutic agent in the treatment of syphilis
II. Used as a tonic in fowler’s solution…..(fowler’s solution used to treat trypanosomiasis involving CNS)

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14
Q

The average of daily intake of arsenic from environmental sources is

A

Less than 1mg

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15
Q

The total burden of arsenic in an adult is about

A

20mg

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16
Q

GIT absorption of Arsenic compounds is a function of their

A

Solubility

17
Q

Absorption of arsenic through the skin is a function of its

A

Lipid solubility

18
Q

Which of the forms of arsenic is more lipid soluble

A

Trivalent form

Pharmac (27 decks)

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