1.37 Meningitis Casse Flashcards Preview

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Flashcards in 1.37 Meningitis Casse Deck (11):
1

What are the initial symptoms of meningitis?

Malaise, myalgia, pyrexia, fluish, headache, nausea, photophobia and rash

2

What are the causes of a headache?

Primary - tension type due to high BP, and dehydration; Migraine
Secondary - non infectious - sub arachnoid heamorrhage
Non CNS - flu, colds etc.

3

What kind of headache is presented with meningitis?

All over, neck stiffness, increased with any movement

4

What types of meningitis are there?

Bacterial, Fingal, Viral and Opportunistic

5

What is Kerning's sign?

Positive - an indication usually present in meningitis that consists of pain and resistance on attempting to extend the leg at the knee with the thigh flexed at the hip - stretches the meninges

6

what does a meningococcal septicaemia lead to?

immune respone to the liposaccharides of the bacteria
release TNF-alpha and IL-1
toxic mediators released
leaky capillaries
low BP
and neutrophil release which release NO

7

How does a meningococcal infection affect blood clotting?

release TNF-alpha and IL1
tissue factors, activates thrombin
activates thrombodulin
inactivates protein c
increases clotting and reduce inhibition of clotting

8

What is the treatment for meningitis?

Antibiotics, circulatory support

9

Why is a CT necessary before lumbar puncture?

To prevent the possibility of a herniation in the brain

10

What are the contraindications of Lumbar Puncture?

no imaging: Seizures, GCS, Brainstem compression, ocular palsies and pupillary dilation, raised pressure,
imaging:low anticoagulation, purpuric rash, uncontrolled hypertension

11

What are the difference in CSF you can get?

Viral - turbid, high lymphocytes, nil polymorphs (granulocytes), low protein, low glucose
Pyogenic - turbid/purulent, high lymphocytes, high polymorphs, high protein, low glucose
TB - turbid/viscous, high lymphocytes, high polymorphs, high protein, extremely low glucose