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MTAP 2 Serology > 1.2 Ab Reactions, intermolecular force and Zonal reactions > Flashcards

1.2 Ab Reactions, intermolecular force and Zonal reactions Flashcards

1
Q

These are foreign substances that contain binding sites

A

Antigens

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2
Q

This binding site for antigens is called antigenic determinant which is known as?

A

Epitope

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3
Q

Antigens can have more than one epitope

T or F

A

T

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4
Q

An antigen that has only one epitope (Incomplete antigens) that cannot stimulate immune response

A

Haptens

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5
Q

These are immunoglobulins that contains glycoprotein and binds to antigen

A

Antibody

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6
Q

These are antigens that can stimulate an immune response

A

Immunogens

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7
Q

All immunogens can be antigen but not all antigen is immunogens

T or F

A

T

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8
Q

Immunogens can posses epitope

T or F

A

T

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9
Q

Part of Antibody that can be seen in the terminal end of the Fab region that binds to antigen

A

Paratope

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10
Q

Combination of a Ag and its corresponding Ab is called?

A

Sensitization

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11
Q

Properties of immune complex is invisible and precise

T or F

A

T

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12
Q

Properties of immune complex where a concept of antibody binds to there corresponding antigen is called lock and key concept

T or F

A

T

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13
Q

Properties of immune complex is irreversible

T or F

A

F

Reversible

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14
Q

Properties of immune complex that the binding of this is covalent

T or F

A

F

Non covalent

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15
Q

Properties of immune complex is goverened by?

A

Law of mass Action

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16
Q

Intramolecular forces:

Occur between oppositely charged particles

A

Ionic or Electrostatic

17
Q

Intramolecular forces:

Occur when Ag and Ab are in close proximity; attraction between polar molecules

A

Hydrogen bonds

18
Q

Intramolecular forces:

Occur because of interaction between the electron clouds of oscillating dipoles

A

van der Waals

19
Q

Intramolecular forces:

Occur between non-polar molecules

A

Hydrophobic bonds

20
Q

Strength of the binding of the EPITOPE and ANTIBODY

A

Affinity

21
Q

Overall binding strength between multivalent antibodies and Antigens

A

Avidity

22
Q

What type of antibody associated mostly in Affinity?

A

IgG

23
Q

What type of antibody is associated mostly with Avidity?

A

IgM

24
Q

The higher the avidity the more likely the immune complex to be dissolve

T or F

A

F

Less likely

25
Q

Forming lattice formation, their should a proportional amount of Ag and Ab

T or F

A

T

26
Q

In Zonal Reactions:

Antibody excess

A

Prozone

27
Q

In Zonal Reactions:

Antigen excess

A

Post zone

28
Q

In Zonal Reactions:

Equal antibody and antigen

A

Zone of Equivalence

29
Q

Prozone and postzone may not produce lattice formation

T or F

A

T

30
Q

Remedy for prozone or postzone?

A

Dilution

31
Q

Zone of Equivalence is the optimal Ag-Ab conc.

T or F

A

T

MTAP 2 Serology (29 decks)

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