9.1 Test for Cold Agglutinins Flashcards
Cold agglutinins are antibodies that react best with RBC at temperature below __°C
37
Cold agglutinins:
The reaction strength is often greatest at __________
0°C to 4°C
A condition where there is a high titer of cold agglutinins causing intravascular agglutination when body is exposed to cold
Cold agglutinin Syndrome
Primary Atypical Pneumonia is caused by?
M. pneumoniae
Abnormal cold IgM abs with anti-I specificity
a. CAS in Primary Atypical Pneumonia
b. CAS in Infectious Mononucleosis
a
Cold autoantibody with anti-i specificity
a. CAS in Primary Atypical Pneumonia
b. CAS in Infectious Mononucleosis
b
Rapid Screening for Cold Agglutinins:
Principle?
Hemagglutination
Rapid Screening for Cold Agglutinins:
Ag: Fresh Huma Group __ Cell
O
Rapid Screening for Cold Agglutinins:
Ab: Cold Agglutinins in patient plasma
T or F
F
Serum
Rapid Screening for Cold Agglutinins:
Results:
Hemagglutination at 4°C, no hemagglutination at 37°C
Positive
Rapid Screening for Cold Agglutinins:
Results:
No Hemagglutination at 4°C, no hemagglutination at 37°C
Negative
